Interleukin polymorphonuclear neutrophil

Cicco, N. A., Lindemann, A., Content, J., Vandenbussche, P., Lubbert, M., Gauss, J., Mertelsmann, R., Herrmann, F. (1990). Inducible production of Interleukin-6 by human polymorphonuclear neutrophils Role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha. Blood 75,2049-52. 

Lindemann, A., Riedel, D., Oster, W., Meuer, S. C., Blohm, D., Mertelsmann, R. H., Herrmann, F. (1988). Granulocyte/macrophage colony-stimulating factor induces interleukin 1 production by human polymorphonuclear neutrophils. J. Immunol. 140, 837-9. 

Ethuin F, Delarche C, Benslama S, Gougerot-Pocidalo MA, Jacob L, Chollet-Martin S Interleukin-12 increases interleukin 8 production and release by human polymorphonuclear neutrophils. J Leukoc Biol 2001 70 439-446. 

Meddows-Taylor S, Martin DJ, Tiemessen CT. Reduced expression of interleukin-8 receptors A and B on polymorphonuclear neutrophils from persons with human immunodeficiency virus type 1 disease and pulmonary tuberculosis. J Infect Dis 1998 177 921-930. 

Abbreviations used in this chapter AZT, 3 -azidothymidine CD, cluster of differentiation CHS, Chediak-Higashi syndrome Con A, concanavalin-A EAE, experimental allergic encephalomyelitis HIV, human immunodeficiency virus HTLV-1, human T-cell leukemia virus-1 IL, interleukin INF, interferon NAC, N-acetyl cysteine NF-kB, neurotrophic factor-k beta PBMC, peripheral blood mononuclear cells PM A, phorbol 12-myristate 13-acetate PMN, polymorphonuclear neutrophil RT, reverse transcriptase TNF-2 tumor necrosis factor alpha. 

In experimentally induced brain focal ischaemia, the upregulation of ICAM-1 and the induction of E- and P-selectm1719 is believed to result from the activity of inflammatory cytokines such as tumor necrosis factor-a (TNF-a) and interleukin-6 (IL-6), which are produced by the ischaemic brain20-21 or by the reoxygenation of microvascular endothelial cells.22 There is a direct association between increased expression of ICAM-1 andE-selectin,19-23 the appearance of inflammatory cytokines,20 and the degree of polymorphonuclear (PMN) cell infiltration into ischaemic tissue. Moreover, cultured murine brain microvascular endothelial cells stimulated with IL-1 () or TNF-a express E-selectin and ICAM-1 and support neutrophil adhesion.24... 

Smith CL, Baker CJ, Anderson DC, Edwards MS Role of complement receptors in opsonophago-cytosis of group B streptococci by adult and neonatal neutrophils. J Infect Dis 1990 162 489-495. Vecchiarelli A, Retini C, Casadevall A, Monari C, Pietrella D, Kozel TR Involvement of C3a and C5a in interleukin-8 secretion by human polymorphonuclear cells in response to capsular material of Cryptococcus neoformans. Infect Immun 1998 66 4324--4330. 

Leung BP, Culshaw S, Grade JA, Hunter D, Canetti CA, Campbell C, Cunha F, Liew FY, Mclnnes IB A role for IL-18 in neutrophil activation. J Immunol 2001 167 2879-2886. Cassatella MA, Guasparri I, Ceska M, Bazzoni F, Rossi F Interferon-gamma inhibits interleukin-8 production by human polymorphonuclear leucocytes. Immunology 1993 78 177-184. 

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