Insurance Study Group

AEC press release, 13 July 1955, AEC/NRC. This press release included the "Preliminary Report of Insurance Study Groups."... 

As has been shown, the POC starts from surface hydroxyl groups which are constantly being newly formed in the cycle by H2O. The existence of these hydroxyl groups was insured when we began our investigations in Germany, it had become known particularly as a result of the studies carried out by BOEHM at al. ( ), which were based on the research results of other authors. 

A large number of wanted and unwanted products can be generated using solid-phase peptide synthesis. To insure quality peptides, it is important to characterize synthesized products with respect to quantity and purity. An array of analytical techniques is needed for peptide analysis one is not enough. Studies performed by the Peptide Synthesis Research Group have shown improved quality of submitted peptides over eight years and have shown the usefulness and necessity of mass spectrometric analysis of peptides. This enhanced capability to characterize wanted and unwanted products should encourage peptide scien-... 

Replacing the hydrogen in 68 with a phenyl group leads to the secondary acetylenic monomer 70. It was believed that this disubstituted acetylene would suppress the reaction of acetylene with itself and insure that there was an acetylene functionality available for reaction with the o-quinodimethane at 200 °G The DSC of 68 showed the presence of a single exothermic peak at 263 °C which the authors felt was adequate evidence for the occurrence of a Diels-Alder reaction between the acetylene and benzocyclobutene. Unfortunately they did not report on any control experiments such as that between diphenylacetylene and simple benzocyclobutene hydrocarbon or a monofunctional benzocyclobutene in order to isolate the low molecular weight cycloaddition product for subsequent characterization. The resulting homopolymer of 68 had a Tg of 274 °C and also had the best thermooxidative stability of all of the acetylenic benzocyclobutenes studied (84% weight retention after 200 h at 343 °C in air). 

Animals in the control groups were pair-fed to their corresponding browned diet treatment animals to insure equal protein intake in both groups. Water was supplied ad libitum and weight gain was monitored throughout the study. 

Numerous epidemiological and clinical study reports confirm that SSRIs cause a high rate of mania in children and youth. Again, as noted earlier in this chapter, Martin et al. (2004) used a national database of more than 7 million privately insured individuals, aged 5-29 years, and found that the highest risk of manic conversion while taking antidepressants was in the 10- to 14-year-old group. 

To make sure that the chain ends indeed do not participate and also to insure that the slight chaise in the ionic concentration with chain length (due to the presence of two ions at the end of the chain in -0 Na terminate polymers) does not lead to erroneous results, polymers possessing both types of chain ends were studied, i. e., those terminated by -OH groups and those terminated by -0 Na groups. 

Studies in the laboratory of M. Shibasaki toward the total synthesis of garsubellin A led to the stereocontrolled synthesis of the 18-ep/-tricyclic core of the natural product/ During the final stages of the synthetic sequence, the tetrahydrofuran ring was installed using a Wacker-type process. The reaction conditions insured that the acetonide protecting group was first removed and the Cl 8 secondary alcohol moiety served as the internal nucleophile to form the tricyclic product. 

---