In vitro toxicology

Eisenbrand, G. et al.. Methods of in vitro toxicology. Food Chem. Toxicol, 40, 193,... 

Sayes, C.M. et al. (2006) Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro. Toxicology Letters, 161 (2), 135—142. 

Crooke, R.M., In vitro toxicology and pharmacokinetics of antisense oligonucleotides, Anti-Cancer Drug Design, 1991, 6, 609-646. 

Scheuhammer, A.M. 1987a. Erythrocyte delta-aminolevulinic acid dehydratase in birds. I. The effects of lead and other metals in vitro. Toxicology 45 155-163. 

Vega, L. et al., Helper T cell subpopulations from women are more susceptible to the toxic effect of sodium arsenite in vitro, Toxicology, 199, 121, 2004. 

Lin, G.H.Y. (1987). Prediction of teratogenic potential and a proposed scheme for teratogenicity screening of industrial research and development materials. In Vitro Toxicology 1 203-217. 

Rylander, L.A., Gandolfi, A.J. and Brendel, K. (1985). Inhibition of organic acid/base transport in isolated rabbit renal tubules by nephrotoxins. In In Vitro Toxicology. A progress report from Johns Hopkins Center for Alternatives to Animal Testing. Vol. 3 (Goldberg, A.M., Ed.). Mary Ann Liebert, New York, pp. 235-247. 

EPA. 1986c. Final report on the evaluation of four toxic chemicals in an in vivo/in vitro toxicological screen Acrylamide, chlordecone, cyclophosphamide, and diethylstilbestrol. Research Triangle Park, NC U.S. Environmental Protection Agency, Health Effects Research Laboratory. EPA-600-1-86-002. 

Mehendale HM, Ray SD, Cai Z. 1991. Paradoxical toxicity of carbon tetrachloride in isolated hepatocytes from chlordecone, phenobarbital and mirex pretreated rats. In Vitro Toxicology 4(3) 187-196. 

Garle MJ, Fry J. 1989. Detection of reactive metabolites in vitro. Toxicology 54 101-110. 

Archakov, A. I. and Bachmanova, G. I. (1995) Cytochrome P450 database for prediction of drugs fate in living systems. In Vitro Toxicology 8, 49-54. 

NT189 Pilotti, A., K. Ancker, E. Arrhenius, and C. Enzell. Effects of tobacco and tobacco smoke constituents on cell multiplication in vitro. Toxicology 1975 5(1) 49-62. 

Enslein, K., Blake, B. W., Tomb, M. E. and Borgstedt. H. H. (1986). In Vitro Toxicology 1, 33-44. TOPKAT Program, Health Designs Incorporated, 183 East Main St., Rochester, New York, USA. 

The particular cell line used in our laboratory, AHH-1 TK-(-/- cells (Crespi and Thilly, 1984), is a versatile indicator cell line for a variety of in vitro toxicological end points (Crespi et al., 1993 Crofton-Sleigh et al.,... 

A.S. Stack, S. Altaman-Hamamdzic, P.J. Morris, S.D. London and L. London, Polychlorinated biphenyls mixtures (Arocolors) inhibit LPS-induced murine splenocyte proliferation in vitro, Toxicology, 139 (1999) 137-154. 

Wildfang, E., Zakharyan, R.A. and Aposhian, H.V. (1998) Enzymatic methylation of arsenic compounds VI. Characterization of hamster liver arsenite and methylarsonic acid methyltransferase activities in vitro. Toxicology and Applied Pharmacology, 152(2), 366-75. 

Change can be expected in almost every aspect of both the applied and the fundamental aspects of toxicology. Risk communication, risk assessment, hazard and exposure assessment, in vivo toxicity, development of selective chemicals, in vitro toxicology, and biochemical and molecular toxicology will all change, as will the integration of all of these areas into new paradigms of risk assessment and of the ways in which chemicals affect human health and the environment. 

Smith PF, Gandolfi AJ, Kmmdieck CL, et al. Dynamic organ culture of precision liver slices for in vitro toxicology. Life Sci 1985 13 1367-1375. 

Fletcher, S.T. and Baker, V.A. Use of proteomic technologies for discovery of new markers for skin irritation in vitro. Toxicological Sciences 2003 72(S-1) 13. 

In Vitro Toxicology, A Journal of Molecular and Cellular Toxicology, journal of the Industrial In Vitro Toxicology Group. Publisher Mary Ann Liebert, Larchmont, NY. 

Sawyer, T.W., Parker, D., Thomas, N., Weiss, M.T., Bide, R.W. (1991a). Efficacy of an oximate-hased skin decontaminant against organophosphate nerve agents determined in vivo and in vitro. Toxicology 67 267-77. 

Sawyer, T.W. (1998a). Characterization of the protective effects of L-nitroarginine methyl ester (L-NAME) against the toxicity of sulphur mustard in vitro. Toxicology 131 21-32. 

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