Antisense, c-mos oligonucleotides

O Keefe, S. J., Wolfes, H., Kiessling, A. A., and Cooper, G. M. (1989). Microinjection of antisense c-mos oligonucleotides prevents meiosis II in maturing mouse eggs. Proc. Natl. Acad. Sci. USA 86 7038-7042. 

Figure 2. Role of c-mos in meiosis of mouse oocytes. Mouse oocytes microinjected with antisense c-mos oligonucleotides fail to progress from meiosis I to meiosis II, instead reforming nuclei following polar body extrusion (O Keefe et al., 1989).

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