In human blood plasma

Frei B, England L, Amos B (1989) Ascorbate is an outstanding anti-oxidant in human blood plasma. Proc Natl Acad Sci USA 86 6377-6381... 

Yang H, Erdos E Second kininase in human blood plasma. Nature 1967 215 1402-1403. 

BURTON G w, JOYCE A and INGOLD K u (1983) First proof that vitamin E is the major hpid-soluble chain-breaking antioxidant in human blood plasma , Lancet, 2, 327-8. 

Burton, G., Joyce, A. and Ingold, K.U. (1983). Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes Arch. Biochem. Biophys. 221, 281-290. 

Frei, B., Stocker, R. and Ames, B.N. (1988). Antioxidant defences and lipid peroxidation in human blood plasma. Proc. Natl Acad. Sci. USA 85, 9748-9752. 

Wayner, D.D., Burton, G.W., Ingold, K.U., Barclay, L.R.C. and Locke, S.J. (1987). Antioxidants in human blood plasma. The relative contributions of vitamin E, urate, ascorbate and protein to the total radical trapping antioxidant activity. Biochim. Biophys. Acta 925, 408-413. 

Everson J, Patterson CC. 1980. "Ultra-clean" isotope dilution/mass spectrometric analyses for lead in human blood plasma indicate that most reported values are artificially high. Clin Chem 26 1603-1607. 

Richter, R., Schulz-Knappe, P., Schrader, M., Standker, L., Jurgens, M., Tammen, H., Forssmann, W.-G. (1999). Composition of the peptide fraction in human blood plasma database of circulating human peptides. J. Chromatogr. B 726, 25-35. 

The equilibrium constants given above for the hydrolysis and protolysis reactions of cis- and trans-DDP can be employed to construct distribution diagrams of various species as a function of the pH. In human blood plasma ([Cl-] = 0.1 M) the dichloro species predominates at about pH 7.4 for both cis- and frans-DDP (Figure 4). By contrast, in intracellular conditions ([Cl ]ambient = 0.004 M) the hydrolysis products dominate, but the distribution behavior of the two isomers is quite... 

Amini N. and Crescenzi C., 2003. Feasibility of an online restricted access materal/liquid chromatography/ tadem mass spectrometry method in the rapid and sensitive determination of organophosphorus trimesters in human blood plasma. J Chromatogr B 795 245. 

Solid-phase borate complexation coupled with RP-HPLC has been employed for the measurement of polyhydroxyflavones in human blood plasma, vegetables and redwine. The chemical structures of polyhydroxyflavones included in the investigation are shown in Fig. 2.87. Vegetables were homogenized, centrifuged and the supernatant was applied for analysis. Human plasma was heparinized before analysis. The outer skins of onion were... 

PolishukZW, Ron M, Wassermann M, et al. 1977b. Pesticides in people Organochlorine compounds in human blood plasma and milk. Pestic Monit J 10(4) 121-129. 

Bilimbin concentration in the measurement of haemoglobin concentration in human blood plasma. 

Some 100 different proteins occur in human blood plasma. Based on their behavior during electrophoresis (see below), they are broadly divided into five fractions albumins and ai-, tt2-, P- and y-globulins. Historically, the distinction between the albumins and globulins was based on differences in the proteins solubility -albumins are soluble in pure water, whereas globulins only dissolve in the presence of salts. 

Figure 5.22 — Reversible flow-through fluorimetric sensor for the determination of potassium in human blood plasma based on the mechanism shown in Fig. 5.21.3. (A) Flow-cell containing the lipophilic membrane. (B) Flow injection conflguration. P pump IV injection valve W waste. For details, see text. (Reproduced from [86] with permission of Elsevier Science Publishers).

Phosphoric acid triesters in human blood plasma have been determined by GC-ICP-MS after SPME,27 after their separation from blood plasma, with detection limits of 50ngl-1 for tripropyl phosphate, 17ngl 1 for tributylphosphate and 24ngl 1 for triphenylphosphate. 

Cellular Glucose Concentration The concentration of glucose in human blood plasma is maintained at about 5 mM. The concentration of free glucose inside a myocyte is much lower. Why is the concentration so low in the cell What... 

The following tabulation gives concentrations not only of K+ and Na+ but also of the other principal ionic constituents in human blood plasma and within cells of skeletal muscle. 1 Units are mmol/kg H20. 

Among the metabolites circulating in human blood plasma after intake of (—)-epicatechin, the major one is the glucuronide [Natsume et ah, 2003]. We suggest that the epicatechin glucuronide serves as transport metabolite, taken up into the cells and after deglucuronidation delivering the flavanol... 

Fibrinogen is a fibrous protein that was first classified with keratin, myosin, and epidermin based on its 5.1 A repeat in wide-angle X-ray diffraction patterns (Bailey et al., 1943), which was later discovered to be associated with the Q-helical coiled-coil structure. It is a glycoprotein normally present in human blood plasma at a concentration of about 2.5 g/L and is essential for hemostasis, wound healing, inflammation, angiogenesis, and other biological functions. It is a soluble macromolecule, but forms a clot or insoluble gel on conversion to fibrin by the action of the... 

Gardiner PE, Stoeppler M. 1987. Optimisation of the analytical conditions for the determination of aluminum in human blood plasma and serum by graphite furnace atomic absorption spectrometry. Part 2. Assessment of the analytical method. J Anal Atom Spectrom 2 401-404. 

Hovander, L. et al., Identification of hydroxylated PCB metabolites and other phenolic halogenated pollutants in human blood plasma, Arch. Environ. Contam. Toxicol., 42, 105-117, 2002. 

Nygren M, Hansson M, Sj str+m M, et al. 1988. Development and validation of a method for determination of PCDDs and PCDFs in human blood plasma A multivariate comparison of blood and adipose tissue levels between Vietnam veterans and matched controls. Chemosphere 17 1663-1692. 

Lima ES, Di Mascio R Rubbo H, Abdalla DS. Characterization of linoleic acid nitration in human blood plasma by mass spectrometry, Biochemistry 2002 41 10717-10722. 

Remane D, Meyer MR, Peters FT et al (2010) Fast and simple procedure for liquid-liquid extraction of 136 analytes from different drug classes for development of a liquid chromato-graphic-tandem mass spectrometric quantification method in human blood plasma. Anal Bioanal Chem 397 2303-2314... 

Saber AL (2009) On-line solid phase extraction coupled to capillary LC-ESI-MS for determination of fluoxetine in human blood plasma. Talanta 78 295-299... 

Beyer J, Peters FT, Kraemer T, Maurer HH (2007) Detection and validated quantification of toxic alkaloids in human blood plasma - comparison of LC-APCI-MS with LC-ESI-MS/MS. J Mass Spectrom 42 621-633... 

H18. Havel, R. J., Kotite, L., and Kane, J. P., Isoelecric heterogeneity of the cofactor protein for lipoprotein lipase in human blood plasma. Biochem. Med. 21, 121—138 (1979). 

Reactions between cisplatin and serum albumin are thought to be the main route for platinum binding in human blood plasma. Several clinical and experimental observations have suggested that albumin-bound platinum may be anticancer active [47] [48]. Additionally, albumin binding may reduce some of the side-effects of cisplatin treatment, especially its nephrotoxicity [49]. The reaction of cisplatin with intact and chemically modified recombinant human albumin (rHA), and with HSA (human serum al-... 

Improvement of the Mass Fragmentographic Technique for Quantification of Tetrahydrocannabinol in Human Blood Plasma... 

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