Identifiers selection

Each glycopeptide CSP has unique selectivity as well as complementary characteristics, and a considerable number of racemates have been resolved on all three of them. Interestingly, most of the resolved enantiomers have the same retention order on these macrocyclic CSPs. When they are mixed or coupled with each other, the selectivity on one CSP will not be canceled by another. Even if some compounds may not have the same retention order, the complementary effects will result in an identifiable selectivity. Therefore, the coupled chiral columns can be used as a screening tool and save chromatographers substantial time in method development. 

When certain drug s are administered with insulin, a resultant decrease or increase in hypoglycemic effect can occur. Display 49-1 identifies selected dragp that decrease the hypoglycemic effect of insulin. 

Multiple drug interactions may occur with the glucocorticoids. Table 50-2 identifies select clinically significant interactions. 

Table 1 lists some taxa, sponges and mollusks from which isonitrile-related compounds were isolated. The partial list identifies selected sponges at the genus level with the geographical origin and compound type. 

In some cases it is necessary unambiguously to identify selected components separated during gas chromatographic examination of oil spill material. Such methods are needed from the standpoint of the enforcement of pollution control laws. The coupling of a mass spectrometer to the separated components emerging from a gas chromatographic separation column enables such positive identifications to be made. 

In these problems, given a list of feasible candidates, the objective is to identify/select the most appropriate product based on a set of product performance criteria. 

When the problem is identified, select a pesticide that will control the problem but damage few other organisms. A properly selected treatment is more likely to be effective and less likely to damage beneficial insects and other non-target organisms. 

FSIS laboratories also use chemical techniques and instrumentation to identify select antibiotic residues. The tetracyclines of interest are identified by thin layer chromatography. Sulfonamides are detected and quantified by fluorescence thin lay chromatography and confirmed by gas chromatography/mass spectrometry. Amoxicillin and gentamycin are identified and/or quantified by high pressure liquid chromatography. Similar techniques are used to identify ionophores and other antimicrobials of interest. 

Identify Select Features 3. Offer Subjective Description... 

Table 8-1. Muscarinic Receptor Subgroups and Their Antagonists. (Acronyms Identify Selective Antagonists Used in Research Studies Only.) ...

Initially, proteins in a sample are separated according to their isoelectric point in a pH-gradient. Next, the proteins are separated according to size on a SDS-polyacrylamide gel. A dye marker such as coomassie blue, silver or fluorescent dyes then detect the resolved proteins. In order to analyze differentially expressed protein spots in an experimental set of gels a computerized detection and matching system is required. Finally, MS identifies selected protein spots. 

From the answers given in the interview study, it is possible to identify selection criteria but not to rank them in relation to how often they are used or how common they are. 

Table 18.3 Identified selection criteria for themes and objects to inspect (Johansson 2006 142)...

This chapter has illustrated the numerous advances made toward identifying selective PDE inhibitors. Despite the heterogeneity that may appear at first glance, several common structural features have become clear. The majority of compounds can be grouped into families of common substructures that address conserved features of the PDE active site. Most notably, the substrate-like cGMP-PDE5 inhibitors, the structurally unrelated indoline derivatives, and the cAMP-PDE4... 

Use mass spectra to determine molecular weights and base peaks, to distinguish between hydrocarbons, and to identify selected functional groups by their fragmentation patterns. 

---