Hydrophilic polymers coatings

In 1995, a report using ACE-MS was published (87). Chu et al. reported on the development of a simple, one-step procedure for the on-line separation and identification of ligands that again bind most tightly to a receptor. Vancomycin was again chosen as the receptor, and it was used in the electrophoretic buffer to completely fill the capillary. In order to prevent vancomycin from flowing into the MS, the electrophoretic buffer pH was chosen to prevent the vancomycin from migrating. A neutral, hydrophilic, polymer-coated capillary was used to minimize EOF in the capillary and to therefore reduce the vanco-... 

LaPorte, R.J. Hydrophilic Polymer Coatings for Biomedical Devices Technomic Lancaster, 1997. 

Tsuji, H. and Ishida, T. (2003) Surface hydrophUicity and enzymatic hydrolyzability of biodegradable polyesters 2. Effects of hydrophilic polymer coating. Macromolecular Bioscience, 3,51-59. 

Jansen B, Goodman LP, Ruiten D. Bacterial adherence to hydrophilic polymer-coated polyurethane stents. Gastrointest Endosc September 1993 39(5) 670-3. 

LaPorte, R. J. (1997). Hydrophilic Polymer Coatings for Medical Devices. Technomic Publishing Company, Lancaster, PA,... 

LaPorte RJ (1997) Considerations for development and manufacture. In Hydrophilic polymer coatings for medical devices. CRC, Boca Raton... 

Taskier HT (1982) Hydrophilic polymer coated microporous membranes capable of use as a battery separator. U.S. Patent 4,359,510... 

Numerous applications of polymer-coated silicas to chromatography of biopolymers allow one to conclude that adsorbed or grafted hydrophilic nonionizing... 

To improve chromatographic separation, another analytical column could be used in addition to the monolith (Xu et al. 2006). The monolith column served as an extraction column only. Hsieh et al. (2000, 2002) utilized a polymer-coated mixed function (PCMF) Capcell C8 column (4.6 x 50 mm, Phenomenex) to provide dual functions—online plasma extraction and analyte separation. The silica was coated with a polymer containing both hydrophilic polyoxythylene and hydrophobic groups. The diluted plasma samples (1 1 to 1 3) were injected directly. No column deterioration was observed after 200 injections. 

Several attempts were made to influence the biodistribution of microspheres. The site of embolization depends on the site of administration and on the diameter of the microspheres [335]. Block copolymers have been used to coat the microspheres with the aim to prevent the recognition by the RES [9, 336-338] or to target them to the bone marrow [339], Interesting results in changing the body distribution of coated microspheres have been obtained. However, it appears that covalent attachment of hydrophilic polymer chains, e.g., PEG chains, is the better way [340]. 

Another attempt by Tricas et al. to modify the surface of carbon black was by the plasma polymerization of acrylic acid [34]. Treatment with acrylic acid made carbon black hydrophilic. Plasma-coated carbon black was mixed with natural rubber and showed increased filler-filler interaction. The bound rubber content was reduced after the surface treatment of the filler. The authors also concluded that the surface of the carbon black was completely covered by the plasma polymer film, preventing the carbon black surface from playing any role in the polymer matrix. 

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