Humulin 70/30, Novolin

Aspart protamine/aspart) Humulin 70/30, Novolin 0.5-1 Dual Up to 10-16... [Pg.348]

Humulin 70/30 Novolin 70/30 70% isophane suspension 30% zinc crystalline Intermediate-acting, faster onset, longer duration Start, 0.5 h peak, 2-12 h end, up to 24 h... [Pg.456]

Commercially available insuhns differ in their onset of action, maximal activity, and duration of action (Table 67.3). They can be classified as rapid acting (0-5 hours), short acting (0-8 hours), intermediate acting (2 to 16 hours), and long acting (4 to 36 hours). Human insulin (e.g. Humulin, Novolin) produced by rDNA technology is now widely available and has largely supplanted in-... [Pg.768]

Novolin is available in four formulations Regular (R), NPH (N), Lente (L), and Novolin 70/30. They correspond to the several formulations of Humulin. Novolin 70/30, Novolin N, and Novolin R are supplied in prefilled cartridges and in prefilled disposable syringes. Velosulin BR is a sterile solution of human insulin (rDNA origin) in a phosphate buffer. [Pg.216]

Human Insulin (Recombinant) Humulin, Novolin, Velosulin BR 215... [Pg.555]

NPH Isophane Human Insulin Suspension. NPH isophane insulin, also called Humulin N, Insulatard NPH Human, or Novolin N is an intermediate-acting form of human insulin produced by recombinant DNA techniques. Mixtures Humulin 70/30 and Novolin 70/30 contain 70% NPH isophane and 30% regular, whereas Humulin 50/50 contains 50% NPH isophane and 50% regular. It is adrninistered subcutaneously and should not be given intravenously. Absorption is delayed because the insulin is conjugated with protamine in a complex of reduced isoelectric solubiUty. Therapeutically, this preparation is probably comparable to purified porcine NPH insulin. However, human NPH insulin may have a slightly shorter duration of action than comparable purified porcine products. [Pg.340]

Injection 100 units/mL (human insulin [rDNA]) otc) Humulin 70/30 (Lilly), Novolin 70/30 (Novo Nordisk), Novolin 70/30 Prefilled (Novo Nordisk)... [Pg.289]

Brand Name(s) Intermediate- and short-acting mixtures Humulin 50/50, Humulin 70/30, Humalog Mix 75/25, Humalog Mix 50/50, Novolin 70/30, Novolog Mix 70/30 Cfiemical Class Exogenous insulin... [Pg.629]

Rapid Acting Humulin R, Novolin R, Novolog, Humalog, Regular Ilefin II. [Pg.629]

Manufacturers Eli Lilly, Indianapolis, IN (Humulin), Novo Nordisk, Bagsvaerd, Denmark (Novolin, Velosulin BR) and Novo Nordisk Pharmaceutical Industries, Inc., Princeton, NJ (Novolin)... [Pg.215]

Approval date 1 February 1996 (Novolin) 1 July 1999 (Velosulin) 22 October 1982 (Humulin)... [Pg.215]

Route of administration Humulin 50/50, Humulin 70/30, Humulin L, Humulin N, Humulin R, Humulin R (U-500), and Humulin U are for subcutaneous injection only. The same applies to formulations containing Novolin. Velosulin BR is indicated... [Pg.216]

Regular insulin 0.5-1 2-4 5-7 Humulin R Novolin R Regular lletin II... [Pg.484]

Isophane insulin 3-4 6-12 18-28 Humulin N Novolin N NPH Insulin NPH Purified Insulin NPH lletin II... [Pg.484]

Insulin zinc 1-3 8-12 18-28 Humulin L Novolin L Lente Insulin Lente Insulin II... [Pg.484]

Human insulin from E coli is available for clinical use as Humulin (Lilly) and dispensed as either regular, NPH, lente, or ultralente Humulin. Human insulin prepared biosynthetically in yeast is marketed by Novo Nordisk as human insulin injection in regular, lente, and NPH forms Novolin R, Monotard Human Insulin (Novolin L), and Novolin N. The same company also produces a human insulin marketed as Velosulin (regular) that contains a phosphate buffer. This reduces aggregation of regular insulin molecules when used in infusion pumps. However, because of the tendency of phosphate to precipitate zinc ions, Velosulin should not be mixed with any of the lente insulins. [Pg.994]

Insulin Humalog , Humulin , Iletin , Novolin , Velosulin ... [Pg.374]

Human insulin Humulin (Eli Lilly) Novolin (Novo Nordisk) Velosulin BR (Novo Nordisk) Insulin-dependent diabetes mellitus... [Pg.270]

Humulin L Novolin L 70% zinc-insulin crystalline suspension 30% amorphous insulin (cloudy suspension) Intermediate-acting, slower onset, longer duration Start, 2.5 h peak, 7-15 h end, 22 h... [Pg.456]

Humulin products (Eli Lilly Company) contain recombinant human insulin derived from Escherichia coli Novolin products (Novo Nordisk) are recombinant human insulin derived from Saccharomyces cerevisiae both companies also sell other forms of recombinant human insulin and may have additional forms (formulations or new drugs) in clinical trials. [Pg.456]

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