Human immunodeficiency virus dendritic cells

Ayehunie S, Garcia-Zepeda EA, Hoxie JA, et al. Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors. Blood 1997 90(4) 1379-1386. 

In a biopsy of an AIDS patient s enlarged thymus (P4), the adipose involuted thymus, with persistence of many Hassall s corpuscles, was judged to be a large lymphoid follicular hyperplasia. This follicular hyperplasia was similar to that described for lymph nodes, spleen, and other lymphoid tissues at earlier stages of human immunodeficiency virus infection, before the development of acquired immune deficiency syndrome. Human immunodeficiency virus RNA and p 24 were detected in the hyperplastic germinal centers (lymphocytes and follicular dendritic infected cells) and also in many cells that may have been either lymphocytes or epithelial cells in the interfollicular areas. 

Cameron, P.U., Freudenthal, P.S., Barker, J.M., Gezelter, S., Inaba, K., Steinman, R.M., 1992. Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4 -I- T cells. Science 257, 383-387. 

Patterson S, Rai A, Hockey N et al. Plasmacytoid dendritic cells are highly susceptible to human immunodeficiency virus type 1 infection and release infectious virus. J Virol 2001 75 6710-6713. 

Cytokine responsive gene 2 Cytotoxic T lymphocyte Dendritic cell Epidemic polyarthritis Formalin-inactivated RSV Fractalkine Gamma interferon Glycosaminoglycans Heparin-binding domains Herpes simplex virus Human cytomegalovirus Human herpesvirus Human immunodeficiency virus Human leukocyte antigen Interferon... 

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