Human Chorionic Gonadotropin hCG

The implantation of the fertilized ovum at a site other than the endometrium is known as ectopic pregnancy. 

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Are involved in biologic activity, eg, of human chorionic gonadotropin (hCG)... 

Morphologically, this is demonstrated by the development of a multinuclear syncytium with apical microvilli [49], while functional differentiation is associated with induction and synthesis of hormones, such as human chorionic gonadotropin (hCG) and human placental lactogen (hPL) [50, 51]. Cultures of primary cytotrophoblasts have been used to study functional expression of P-gp, amino acid uptake, and hormonal stimulation of amino acid uptake and... 

Aizawa et al. developed immunosensors of the first type for syphilis and blood typing [228-230] based on measurements of the transmembrane potential across an immunoresponsive membrane. The potentiometric immunosensor using an antibody against human chorionic gonadotropin (hCG)... 

The menotropins, human menopausal gonadotropin (HMG) and urofollitropin are prepared from the urine of postmenopausal women. HMG has approximately equal amounts of FSH an LH. Urofollitropin has only FSH activity. Follitropin alpha and follitropin beta are two FSH products which are made with recombinant DNA technology. Lutropin alpha is recombinant human LH. Human chorionic gonadotropin (HCG) is produced in the placenta and excreted in the urine. It has mainly LH activity. Choriogonadotropin alpha is the world s first recombinant chorionic gonadotropin (r-hCG) for the treatment of anovulation, the most common cause of infertility in women. 

Hormones Human chorionic gonadotropin (HCG), placental extracts Novarel NA... 

A 32-year-old woman who was not obese developed benign intracranial hypertension in association with ovarian hyperstimulation syndrome after ovulation induction using goserelin, follitropin, and human chorionic gonadotropin (hCG) (3). The syndrome did not recur during a second pregnancy in which follitropin and hCG were not used... 

A 29-year-old woman with polycystic ovary syndrome had her first in vitro fertilization cycle of leuprorelin acetate, FSH, and human chorionic gonadotropin (hCG) (67). Within 2 days she complained of abdominal distension, shortness of breath, and abdominal pain. Over the next few days she developed massive ovarian enlargement, ascites, hyponatremia, respiratory failure, and renal insufficiency. This was further complicated by duodenal perforation, probably due to severe physical stress. 

Along this line Matsue et al. [37,45,78,79] have developed a number of biochips. Among them are multi-analyte assays for human placental lactogen (HPL) and human chorionic gonadotropin (HCG) [45] and leukocidin, a toxic protein produced by methicillin-resistant Staphylococcus aureus [79]. Figure 37.8 shows an example of a dual immunoassay with SECM detection. The analyte is defined by the position on the chip and the amount of analyte is quantified via the collection current at the UME. The current originates from the reduction of ferrocinium methanol (Fc+) at the UME. Fc+ is produced locally at the chip surface by the enzyme HRP under consumption of H202. 

Kowari, K., et al. 2002. Pharmacokinetics and pharmacodynamics of human chorionic gonadotropin (hCG) after rectal administration of hollow-type suppositories containing hCG. Biol Pharm Bull 25 678. 

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