Glycosaminoglycan binding

Cox JH, Dean RA, Roberts CR et al (2008) Matrix metalloproteinase processing of CXCLl 1/I-TAC results in loss of chemoattractant activity and altered glycosaminoglycan binding. J Biol Chem... 

Lau EK, Paavola CD, Johnson Z, et al. Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1 implications for structure and function in vivo. J Biol Chem 2004 279 22294-305. 

Proudfoot AE, Handel TM, Johnson Z, et al. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proc Natl Acad Sci U S A 2003 100 1885-90. 

RE Hileman, JR Fromm, JM Weiler, RJ Linhardt. Glycosaminoglycan-protein interactions definition of consensus sites in glycosaminoglycan-binding proteins. Bioessays 20 156-167, 1998. 

Heparin cofactor II is a second plasma SERPIN which has resemblance to antithrombin in that it is activatable by glycosaminoglycan binding. This protein has also been called antithrombin BM, dermatan sulfate cofactor, and human leuserpin 2 (88). The existence of this second inhibitor and heparin cofactor was first shown by Briginshaw in 1974 (89). Whereas antithrombin is observed to have progressive antithrombin activity and to also inhibit factor Xa, the second... 

Blackwell and his co-workers have used circular dichroism spectroscopy to study the interactions of glycosaminoglycans with collagen, and with synthetic cationic polypeptides. In the absence of glycosaminoglycans, poly-L-lysine and poly-L-arginine exist in an extended charged coil conformation. Glycosaminoglycans bind to these cationic polypeptides and cause them to assume an a-helical conformation. In a series of systematic studies (76-83). Blackwell and his co-workers... 

Grammatikakis, N. et al., A novel glycosaminoglycan-binding protein is the vertebrate homologue of the cell cycle control protein, Cdc37, J. Biol. Chem., 270, 16198, 1995. 

Laterra, J., Silbert, J. E., and Culp, L. A., Cell surface heparan sulfate mediates some adhesive responses to glycosaminoglycan-binding matrices including fibronectin. J. Cell Biol. 96, 112-121 (1983). 

Mercey E, Sadir R, Maillart E, Roget A, Baleux F, Lortat-Jacob H, Livache T (2008) Polypyrrole oligosaccharide array and surface plasmon resonance imaging for the measurement of glycosaminoglycan binding interactions. Anal Chem 80 3476-3482... 

Possesses a glycosaminoglycan binding site bSerpin domain Kunitz domain... 

Prevents early agent replication in the LRS, competes with GAG (glycosaminoglycan) binding site... 

Mbemba E, Gluckman JC, Gattegno L. Glycan and glycosaminoglycan binding properties of stromal cell-derived factor (SDF)-lalpha. Glycobiology 2000 10 21-29. 

Seet BT, Barrett J, Robichaud J et al. Glycosaminoglycan-binding properties of the myxoma virus CC-chemokine inhibitor, M-Tl. J Biol Chem 2001 21 21. 

Proudfoot, A. E., Handel, T. M., Johnson, Z., Lau, E. K., LiWang, P., Clark-Lewis, I., etal. (2003). Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines. Proceedings of the National Academy of Sciences of the United States of America, 100, 1885-1890. 

Chakravarty, L., Rogers, L., Quach, T., Breckenridge, S., Kolattukudy, P. E. (1998). Lysine 58 and histidine 66 at the C-terminal alpha-hehx of monocyte chemoattractant protein-1 are essential for glycosaminoglycan binding. Journal of Biological Chemistry, 273, 29641-29647. 

Ah, S., Robertson, H., Wain,J. H., Isaacs, J. D., Mahk, G., Kirby, J. A. (2005). A non-glycosaminoglycan-binding variant of CC chemokine hgind 7 (monocyte chemoattractant protein-3) antagonizes chemokine-mediated inflammation. The Journal of... 

Ruiz-Arguello MB, Smith VP, Campanella GS et al. An ectromelia virus protein that interacts with chemokines through their glycosaminoglycan binding domain. J Virol 2008 82(2) 917-926. 

Koopmann, W, Ediriwickrema, C., and Krangel, M.S. (1999) Structure and function of the glycosaminoglycan binding site of chemokine macrophage-inflammatory protein-1 beta. Journal of Immunology (Baltimore, Md 1950), 163, 2120-2127. 

Koopmann, W. and Krangel, M.S. (1997) Identification of a glycosaminoglycan-binding site in chemokine macrophage inflammatory protein-l-alpha. The Journal of Biological Chemistry, 272, 10103-10109. 

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