Glutathione-S-transferases polymorphisms

HONG w K and wu x (2000) Dietary intake of isothiocyanates evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk . Cancer Epidemiol Biomarkers Prev, 9 1017-20. 

Hayes JD, Strange RC. Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology 2000 61 154-166. 

Davies SM, Robison LL, Buckley JD et al. Glutathione S-transferase polymorphisms and outcome of chemotherapy in childhood acute myeloid leukemia. J Clin Oncol 2001 19 1279-1287. 

Layton, M.A., et al., "The Therapeutic Response to D-Penicillamine in Rheumatoid Arthritis Influence of Glutathione S-Transferase Polymorphisms," Rheumatology (Oxford), 38, 43-47 (1999). 

Spitz, M.R., Duphorne, C.M., Detry, M.A., Pillow, P.C., Amos, C.I., Lei, L., deAndrade, M., Gu, X., Hong, W.K. and Wu, X. (2000) Dietary intake of isothiocyanates evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk. Cancer Epidemiol. Biomarkers Prev., 9,1017-20. 

Lebmn, S., Golka, K., Schulze, H. Follmann, W. (2006) Glutathione S-transferase polymorphisms and ochratoxin A toxicity in primary human urothelial cells. Toxicology 224, 81-90. 

Seow A, Yuan JM, Sun CL, Van Den Berg D, Lee HP, Yu MC. Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis. 2002 23 2055-2061. 

Moore, L. etal. (2007) Glutathione S-transferase polymorphisms, cruciferous vegetable intake, and cancer risk in the Central and Eastern Eiuopean Kidney Cancer Study. Carcinogenesis... 

Recent studies focused on the importance of pharmacogenetic determinants of response in cancer patients. Screening of patients for polymorphic mutants of glutathione-S-transferase and thymidylate synthase has the potentiality to predict response and hence outcome of chemotherapy. 

Sweeney C, McClure GY, Fares MY et al. Association between survival after treatment for breast cancer and glutathione S-transferase PI Ilel05Val polymorphism. Cancer Res 2000 60 5621-5624. 

Anderer G, Schrappe M, Brechlin AM et al. Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia. Pharmacogenetics 2000 10 715-726. 

J. G. Hengstler, M. Arand, M. E. Herrero, F. Oesch, Polymorphism of A-Acetyltransfe-rase, Glutathione S-Transferases, Microsomal Epoxide Hydrolase and Sulfotransferase Influence on Cancer Susceptibility , Recent Results Cancer Res. 1998, 154, 47 - 85. 

Stoehlmacher, J., Park, D. J., Zhang, W., et al. (2002) Association between glutathione S-transferase PI, Tl, and Ml genetic polymorphism and survival of patients with metastatic colorectal cancer. J. Natl. Cancer Inst. 94, 936-942. 

Ambrosone CB, Coles BF, Freudenheim JL, Shields PG (1999) Glutathione-s-transferase (gstml) genetic polymorphisms do not affect human breast cancer risk, regardless of dietary antioxidants. J Nutr 129 565-568... 

Katoh T, Yamano Y, Tsuji M, Watabane M (2008) Genetic polymorphisms of human cytosol glutathione S-transferases and prostate cancer. Pharmogenomics 9 93-104... 

Mitrunen K, Jourenkova N, Kataja V et al (2001) Glutathione s-transferase ml, m3, pi, and tl genetic polymorphisms and susceptibility to breast cancer. Cancer Epidem Biomar 10 229-236... 

Helzlsouer KJ, Selmin O, Huang HY et al (1998) Association between glutathione s-transferase ml, pi, and tl genetic polymorphisms and development of breast cancer. J Natl Cancer 1 90 512-518... 

Ueda M, Hung YC, Terai Y et al. Glutathione S-transferase GSTMl, GSTTl and p53 codon 72 polymorphisms in human tumor cells. Hum Cell 2003 16 241-251. 

Goekkurt E, Eloehn S, Wolschke C et al. Polymorphisms of glutathione S-transferases (GST) and thymidylate synthase (TS) novel predictors for response and survival in gastric cancer patients. Br J Cancer 2006 94 281-286. 

Pemble, S., Schroeder, K.R., Spencer, S.R., Meyer, D.J., Hallier, E., Bolt, H.M., Ketterer, B. Taylor, J.B. (1994) Human glutathione S-transferases theta (GSTTI) cDNA cloning and the characterization of a genetic polymorphism. Biochem. J., 300, 271-276... 

Dynamic Docking Study of the Binding of l-Chloro-2,4-Dinitrobenzene in the Putative Electrophile Binding Site of Naturally Occurring Human Glutathione S-Transferase pi Allelo-Polymorphic Proteins... 

N. P. Genetic Polymorphisms of Human V-acetyltrans-ferase, Cytochrome P450, Glutathione-S-transferase, and Epoxide Hydrolase Enzymes Relevance to Xenobiotic Metabolism and Toxicity. Crit. Rev. Toxicol. 1999, 29, 59-124. 

Bredschneider M, Klein K, Murdter TE, Marx C, Eichelbaum M, Nussler AK, Neuhaus P, Zanger UM, Schwab M. Genetic polymorphisms of glutathione S-transferase Al, the major glutathione S-transferase in human liver consequences for enzyme expression and busulfan conjugation. Clin Pharmacol Ther 2002 71 479 487. 

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