Glue, surgical

Uses. In high-bond strength, fast-acting glues (e.g., Krazy Glue) surgical use as tissue... 

The extent to which these new tissue adhesives and hemostats will influence surgical procedures can be seen in the following analogy. An effective carpenter cannot create a masterpiece without a saw to cut wood, nails to ensure local fixation of separate pieces of wood, and glue to cause broad surface apposition between wood surfaces. Similarly, the surgeon presently uses a scalpel to cut and divide tissues as well as a suture to create local fixation of tissues, but until... 

Alkyl-2-cyanoacrylates are readily polymerized in the presence of weak bases such as water. Because of the presence of the strong polar cyano pendant group these polymers (e.g. Super Glue) are excellent adhesives. Polybutyl-2-cyanoacrylate is tolerated by the body better than its lower alkyl homo-logues. Hence polybutyl-2-cyanoacrylate is used as an adhesive aid to stop bleeding in some surgical operations. 

Cyanoacrylate has been used for sealing corneal perforations, but it is not smooth or malleable, and it exhibits a hard tissue-scratching surface and requires the patient to use a soft contact lens for comfort. Another surgical limitation when using cyanoacrylate is the immediate polymerization on a wet or moist corneal surface, and that property reduces the time allocated for and increases the difficulty in applying the glue to a precise location in a well-controlled manner. 

The rats are anesthetized and undergo an aseptic procedure to implant the aortic catheter distal to the renal arteries. The catheter is secured using cyanoacrylate glue. The transmitter and battery unit are placed in the abdomen and attached to the abdominal musculature using a suture. After closure of the surgical wound, the animals are giving sufficient time to recover from the procedure before being used in a study, usually at least one week. 

The use of adsorbent chemicals, such as zeolites and other haemostatic agents, to seal severe injuries quickly. Thrombin and fibrin glue are used surgically to treat bleeding and to thrombose aneurysms. 

Canonico S. The use of human fibrin glue in the surgical operations. Acta Biomed Ateneo Parmense 2003 74(Suppl 2) 21-5. 

Moon MC, Molnar K, Yau L, Zahradka P. Perivascular delivery of losartan with surgical fibrin glue prevents neo-intimal hyperplasia after arterial injury. J Vase Surg 2004 40(l) 130-7. 

Biodegradable surgical adhesives and glues Drug delivery, hydrogels, and thin films... 

L. Montanaro, C. R. Arciola, E. Cenni, Cytotoxicity, blood compatibility and antimicrobial activity of two cyanoacrylate glues for surgical use, Biomaterials., 22 [1] 59-66 (2001). 

Some physicians take advantage of Krazy Glue s ability to adhere strongly to the skin — they use a professional version of the stuff, called Dermabond, instead of sutures to close surgical wounds. In fact, you can use Krazy Glue at home to close superficial cuts when nothing else is available. 

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