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Glomerular filtration rate , cystatin

Estimation of the glomerular filtration rate (GFR) is considered a sensitive index of functional nephron mass (Newman and Price 1999). Point measurements of the plasma levels of several endogenous small molecules (urea, creatinine, 2-(a-mannopyranosyl)-L-tryptophan) or small (less than 66 kDa) proteins (cystatin C (y-trace), prostaglandin D synthase (15-trace protein), ai-microglobulin, p2-microglobulin, and retinol binding protein) have been used to assess GFR in many species. [Pg.115]

Serum/Plasma Cystatin C as a Marker for Glomerular Filtration Rate (GFR). 72... [Pg.63]

Fig. 8. Correlation between glomerular filtration rate and (top) reciprocal serum cystatin C (mg/liter)... Fig. 8. Correlation between glomerular filtration rate and (top) reciprocal serum cystatin C (mg/liter)...
Fig. 9. Nonparametric ROC plots for the diagnostic accuracy of serum cystatin C and creatinine in distinguishing between normal and reduced glomerular filtration rate (> and < 80 ml/minx 1.73 m2, respectively) in 51 patients with various renal conditions (the same population as the one displayed in Fig. 8). Fig. 9. Nonparametric ROC plots for the diagnostic accuracy of serum cystatin C and creatinine in distinguishing between normal and reduced glomerular filtration rate (> and < 80 ml/minx 1.73 m2, respectively) in 51 patients with various renal conditions (the same population as the one displayed in Fig. 8).
B21. Bokenkamp, A., Domanetzki, M., Zinck, R., Schumann, G., Byrd, D., Brodehl, J., Cystatin C semm concentrations underestimate glomerular filtration rate in renal transplant recipients. Clin. [Pg.91]

G12. Grubb, A., Simonsen, O., Sturfelt, G., Truedsson, L., and Thysell, H., Serum concentration of cystatin C, factor D and 02-microglobulin as a measure of glomerular filtration rate. Acta Med. Scand. 218(5), 499-503 (1985). [Pg.93]

H7. Helin, I., Axenram M., and Grubb, A., Serum cystatin C as a determinant of glomerular filtration rate in children. Clin. Nephrol. 49(4), 221—225 (1998). [Pg.94]

J4. Jung, K., and Jung, M., Cystatin C A promising marker of glomerular filtration rate to replace creatinine [letter]. Nephron 70(3), 370-371 (1995). [Pg.94]

N6. Norlund, L., Fex, G., Lanke, J., Von Schenck, H., Nilsson, J. E., et al., Reference intervals for the glomerular filtration rate and cell-proliferation markers Serum cystatin C and serum fe-microglobulin/cystatin C-ratio. Scand. J. Clin. Lab. Invest. 57(6), 463-470 (1997). [Pg.97]

P7. Plebani, M., Dali Amico, R., Mussap, M., Montini, G., Ruzzante, N., et al., Is serum cystatin C a sensitive marker of glomerular filtration rate (GFR) A preliminary study on renal transplant patients. Renal Fail. 20(2), 303-309 (1998). [Pg.97]

R8. Risch, L., Blumberg, A., and Huber, A., Rapid and accurate assessment of glomerular filtration rate in patients with renal transplants using serum cystatin C. Nephrol. Dial. Transplant. 14(8), 1991-1996 (1999). [Pg.98]

V2. Vinge, E., Lindergard, B., Nilsson-Ehle, P., and Grubb, A., Relationships among serum cystatin C, serum creatinine, lean tissue mass and glomerular filtration rate in healthy adults. Scand. J. Clin. Lab. Invest. 59, 1-6 (1999). [Pg.99]

Keevil BG, Kilpatrick ES, Nichols SP, Maylor PW. Biological variation of cystatin C implications for the assessment of glomerular filtration rate. Clin Chem. 1998 44 1535-1539... [Pg.25]

Coll E, Botey A, Alvarez L, Poch E,Quinto L, Saurina A, Vera M, Piera C, Darnell A Serum cystatin C asa new marker for noninvasive estimation of glomerular filtration rate and as a marker for early renal impairment. Am J Kidney Dis 2000 36 29-34. [Pg.25]

Jonsson AS, Flodin M, Flansson LO, Larsson A. Estimated glomerular filtration rate (eGFR(CystC)) from serum cystatin C shows strong agreement with iohexol clearance in patients with low GFR. Scand J Clin Lab Invest. 2007 9 1 -9. [Pg.122]

Flerget-Rosenthal S, van Wijk JA, Brocker-Preuss M, Bokenkamp A. Increased urinary cystatin C reflects structural and functional renal tubular impairment independent of glomerular filtration rate. Clin Biochem 2007 27 April [Epub ahead of print].This study provides evidence for urinary cystatin C as a biomarker for tubular injury. [Pg.122]

Figure 24-10 Receiver operating characteristic (ROC) curves comparing creatinine and cystatin C in the assessment of GFR. Non parametric ROC plots were constructed to assess the diagnostic accuracy of serum concentrations of cystatin C and creatinine in distinguishing between normal and reduced GFR (less than 80mL/min per 1.73 m ) in 51 patients with various renal conditions. (From Kyhse-Andersen j, Schmidt C, Nordin C, et af. Serum cystatin C, determined by a rapid, automated particle-enhanced turbidimetric method, is a better marker than serum creatinine for glomerular filtration rate. Clin Chem 1994 40 l92l-6.)... Figure 24-10 Receiver operating characteristic (ROC) curves comparing creatinine and cystatin C in the assessment of GFR. Non parametric ROC plots were constructed to assess the diagnostic accuracy of serum concentrations of cystatin C and creatinine in distinguishing between normal and reduced GFR (less than 80mL/min per 1.73 m ) in 51 patients with various renal conditions. (From Kyhse-Andersen j, Schmidt C, Nordin C, et af. Serum cystatin C, determined by a rapid, automated particle-enhanced turbidimetric method, is a better marker than serum creatinine for glomerular filtration rate. Clin Chem 1994 40 l92l-6.)...
Bokenkamp A, Domanetzi M, Zinck R, Schumann G, Byrd D, Brodehl J. Cystatin C—a new marker of glomerular filtration rate in children independent of age and height. Pediatrics 1998 101 875-81. [Pg.827]

Bostom AG, Dworkin LD. Cystatin C measurement improved detection of mild decrements in glomerular filtration rate versus creatinine-based estimates. Am J Kidney Dis 2000 36 205-7. [Pg.827]

Harmoinen A, Lehtimaki T, Korpela M, Turjanmaa V, Saha H. Diagnostic accuracies of plasma creatinine, cystatin C, and glomerular filtration rate calculated by the Cockcroft-Gault and Levey (MDRD) formulas. Clin Chem 2003 49 1223-5. [Pg.829]

Laterza OF, Price CP, Scott MG. Cystatin C an improved estimator of glomerular filtration rate Clin Chem 2002 48 699-707. [Pg.830]

Ylinen EA, Ala-Houhala M, Harmoinen APT, Knip M. Cystatin C as a marker for glomerular filtration rate in pediatric patients. Pediatr Nephrol 1999 13 506-9. [Pg.834]

Glomerular filtration rate Inulin, sinistrin lothalamate lohexol Tc-diethylenetriaminepentaacetic acid (99mjj.-DTPA) l-lothalamate Creatinine Cystatin C... [Pg.762]

Bokenkamp A, Domanetzki M, Zinck R, et al. Cystatin C serum concentrations rmderestimate glomerular filtration rate in renal transplant recipients. CUn CUem 1999 45 1866-1868. [Pg.778]

Friberg L, Procator M, Norberg GF, Kjellstrom T (editors). Cadmium in the environment. CRC Press, Cleveland 1974. Simonsen 0, Grubb A. Thysell H. The blood serum concentration of cystatin C (g-trace) as a measure of the glomerular filtration rate. Scand J Clin Lab Invest 1985 45 97-101. [Pg.650]

Newman DJ, Thakkar FI, Edwards RG, Wilke M, White T, Grubb AO, Price CP. Serum cystatin C a replacement marker for creatinine as a biochemical marker of glomerular filtration rate. Kidney Int 1994 46 (SuppI 47) S20-S21. [Pg.651]

These plasma tests are used as indirect measurements of the glomerular filtration rate (GFR) to some extent, these endogenous tests supplement each other despite having different limitations. Plasma creatinine, urea, and cystatin C are normally filtered from the plasma, and they are reabsorbed or secreted by the proximal tubules to a minor extent, which differs between species. Tubular secretion leads to overestimation of GFR and it is higher in laboratory animals than in man. These secretions/reabsorption mechanisms may change as a consequence of major tubular injury. In addition to renal injury, the GFR may be altered by changes of renal hemodynamics or extracellular dehydration. [Pg.75]

Almy, F. S., M. M. Christopher, D. P. King, and S. A. Brown. 2002. Evaluation of cystatin C as an endogenous marker of glomerular filtration rate in dog. Journal of Veterinary Internal Medicine 16 45-51. [Pg.91]

Laterza, O. F., C. P. Price, and M. G. Scott. 2002. Cystatin C An improved estimator of glomerular filtration rate Clinical Chemistry 48 699-707. [Pg.91]

See other pages where Glomerular filtration rate , cystatin is mentioned: [Pg.75]    [Pg.78]    [Pg.94]    [Pg.98]    [Pg.828]    [Pg.1796]    [Pg.461]    [Pg.635]    [Pg.96]    [Pg.164]   


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