Glomerular filtration rate , cystatin marker

Serum/Plasma Cystatin C as a Marker for Glomerular Filtration Rate (GFR). 72... 

B22. Bokenkamp, A., Domanetzki, M., Zinck, R., Schumann, G., Byrd, D., and Brodehl, J., Cystatin C—A new marker of glomerular filtration rate in children independent of age and... 

J4. Jung, K., and Jung, M., Cystatin C A promising marker of glomerular filtration rate to replace creatinine [letter]. Nephron 70(3), 370-371 (1995). 

N6. Norlund, L., Fex, G., Lanke, J., Von Schenck, H., Nilsson, J. E., et al., Reference intervals for the glomerular filtration rate and cell-proliferation markers Serum cystatin C and serum fe-microglobulin/cystatin C-ratio. Scand. J. Clin. Lab. Invest. 57(6), 463-470 (1997). 

P7. Plebani, M., Dali Amico, R., Mussap, M., Montini, G., Ruzzante, N., et al., Is serum cystatin C a sensitive marker of glomerular filtration rate (GFR) A preliminary study on renal transplant patients. Renal Fail. 20(2), 303-309 (1998). 

Coll E, Botey A, Alvarez L, Poch E,Quinto L, Saurina A, Vera M, Piera C, Darnell A Serum cystatin C asa new marker for noninvasive estimation of glomerular filtration rate and as a marker for early renal impairment. Am J Kidney Dis 2000 36 29-34. 

Figure 24-10 Receiver operating characteristic (ROC) curves comparing creatinine and cystatin C in the assessment of GFR. Non parametric ROC plots were constructed to assess the diagnostic accuracy of serum concentrations of cystatin C and creatinine in distinguishing between normal and reduced GFR (less than 80mL/min per 1.73 m ) in 51 patients with various renal conditions. (From Kyhse-Andersen j, Schmidt C, Nordin C, et af. Serum cystatin C, determined by a rapid, automated particle-enhanced turbidimetric method, is a better marker than serum creatinine for glomerular filtration rate. Clin Chem 1994 40 l92l-6.)...

Ylinen EA, Ala-Houhala M, Harmoinen APT, Knip M. Cystatin C as a marker for glomerular filtration rate in pediatric patients. Pediatr Nephrol 1999 13 506-9. 

Newman DJ, Thakkar FI, Edwards RG, Wilke M, White T, Grubb AO, Price CP. Serum cystatin C a replacement marker for creatinine as a biochemical marker of glomerular filtration rate. Kidney Int 1994 46 (SuppI 47) S20-S21. 

Almy, F. S., M. M. Christopher, D. P. King, and S. A. Brown. 2002. Evaluation of cystatin C as an endogenous marker of glomerular filtration rate in dog. Journal of Veterinary Internal Medicine 16 45-51. 

Lock ERCJ (1998) Xenobiotic metabolizing enzymes of the kidney. Toxicol Pathol 26(l) 18-25 Madero M, Samak MJ, Stevens LA (2006) Serum cystatin C as a marker of glomerular filtration rate. Curr Opin Nephrol Hypertens 15 610-616... 

DNA sequence The nucleotide sequence data are available from the EMBL, GenBank, and DDBJ Nucleotide Sequence Databases under accession number X52255 Half-life About 20 min (experimentally determined for human cystatin C in rat plasma. The similarity in distribution volume and renal clearance between human cystatin C and acknowledged markers of human glomerular filtration, i.e., iohexol and 51 Cr-EDTA, suggests that the substances are eliminated at the same rate in humans with a half-life of approximately 2 h in individuals with normal renal function)... 

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