Glioma cells, receptors

Zhong, H., Guerrero, S. W., Esbenshade, T. A., and Minneman, K. P. (1996). Inducible expression of 3 - and P2-adrenergic receptors in rat C6 glioma cells Functional interactions between closely related subtypes. Mol. Pharmacol. 50 175-184. 

Ping YF, Yao XH, Chen JH, Liu H, Chen DL, Zhou XD, Wang JM, Bian XW (2007) The anticancer compound Nordy inhibits CXCR4-mediated production of IL-8 and VEGF by malignant human glioma cells. J Neurooncol 84 21-29 Pitcher JA, Freedman NJ, Lefkowitz RJ (1998) G protein-coupled receptor kinases. Annu Rev Biochem 67 653-692... 

Bohn LM, Belcheva MM, Coscia CJ (2000) p-opioid agonist inhibition of kappa-opioid receptor-stimulated extracellular signal-regulated kinase phosphorylation is dynamin-dependent in C6 glioma cells. J Neurochem 74 574-581... 

Zhou Y, Larsen PH, Hao C, Yong VW. CXCR4 is a major chemokine receptor on glioma cells and mediates their survival. J Biol Chem 2002 277 49481-7. 

Bajetto A, Barbieri F, Dorcaratto A, et al. Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues role of CXCR4 and SDF1 in glioma cell proliferation and migration. Neurochem Int 2006 49 423—432. 

Tonner LE, Katz DI, Heiman AS. 1997. The acute effect of lead acetate on glucocorticoid receptor binding in C6 glioma cells. Toxicology 116 109-122. 

Investigations of the cellular effects of radiofrequency radiation provide evidence of damage to various types of avian and mammalian cells. These effects involve radiofrequency interactions with cell membranes, especially the plasma membrane. Effects include alterations in membrane cation transport, Na+/K+-ATPase activity, protein kinase activity, neutrophil precursor membrane receptors, firing rates and resting potentials of neurons, brain cell metabolism, DNA and RNA synthesis in glioma cells, and mitogenic effects on human lymphocytes (Cleary 1990). 

A similar mechanism has also been shown to occur in brain cells. For example, continuous exposure of /1-adrenoceptors on rat glioma cells in vitro results in a rapid reduction in the responsiveness of the receptors. This is followed by a secondary stage of desensitization, whereby the number of /1-receptors decreases. It seems likely that the receptors are not lost but move into the cell and are therefore no longer accessible to the transmitter. 

G-22 Transferrin Glioma-associated antigen Transferrin receptor rat glioma cells Glioma cells [83]... 

IL-4 PE38[KDEL] Interleukin-4 Binds to IL-4 receptor overexpressed on myeloma and glioma cells PE38[KDEL] is a binding-deficient variant of Pseudomonas exotoxin (PE) Cytotoxicity Under investigation as a potential intratnmor treatment for patients with glioma [104]... 

McEachern JC, Shaw CA (1996) An alternative to the LTP orthodoxy a plasticity-pathology continuum model. Brain Res Brain Res Rev 22(1) 51—92 Mackie K, Lai Y, Westenbroek R, Mitchell R (1995) Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J Neurosci 15(10) 6552—61 Mackie K, Devane WA, Hille B (1993) Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells. Mol Pharmacol 44(3) 498-503 Mackie K, Hille B (1992) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci USA 89(9) 3825-9... 

C. R. Miller, D. J. Buchsbaum, P. N. Reynolds, J. T. Douglas, G. Y. Gillespie, M. S. Mayo, D. Raben, and D. T. Curiel, Differential susceptibility of primary and established human glioma cells to adenovirus infection targeting via the epidermal growth factor receptor achieves fiber receptor-independent gene transfer, Cancer Res. 58 5138 (1998). 

Le Grand B, Panissie A, Pauwels PJ, John GW. Activation of recombinant h5-HT1B and h5-HT1D receptors stably expressed in C6 glioma cells produces increases in Ca2+-dependent K+ current. Naunyn Schmiedebergs Arch Pharmacol 1998 358 608-615. 

Bartrup JT, Newberry NR. 5-IIT2A receptor-mediated outward current in C6 glioma cells is mimicked by intracellular IP3 release. Neuroreport 1994 5 1245-1248. 

Garcia MC, Kim HY. Mobilization of arachidonate and docosahexaenoate by stimulation of the 5-HT2A receptor in rat C6 glioma cells. Brain Res 1997 768 43-48. 

Miller KJ, Gonzalez HA. Serotonin 5-HT2A receptor activation inhibits cytokine-stimulated inducible nitric oxide synthase in C6 glioma cells. Ann NY Acad Sci 1998 861 169-173. 

Noda M, Yasuda S, Okada M, et al. Recombinant human serotonin 5A receptors stably expressed in C6 glioma cells couple to multiple signal transduction pathways. J Neurochem 2003 84 222-232. 

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