Gene therapy suicide genes

Vascular gene therapy Transfer of dominant-negative receptors or suicide genes under the control of angiogenic endothelial cell specific promoters... 

Degrfeve B, De Clercq E, Balzarini J (1999) Bystander effect of purine nucleoside analogues in HSV-1 tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues. Gene Ther 6 162-170... 

Tanaka, M., N. Inase, S. Miyake, and Y. Yoshizawa. 2001. Neuron specific enolase promoter for suicide gene therapy in small cell lung carcinoma. Anticancer Res 21(lA) 291-4. 

C. J. Springer, I. Niculescu-Duvaz, Prodrug-Activating Systems in Suicide Gene Therapy , J. Clin. Invest. 2000,105, 1161-1167. 

Anderson DG, Peng W, AMnc A, Hossain N, Kohn A, Padera R, Langer R, SawicM JA (2004) A polymer library approach to suicide gene therapy for cancer. Proc Natl Acad Sd USA 101 16028-16033... 

D. Nafziger, J. Pegg, D. Paielli, S. Brown, K. Barton, M. Lu, E. Aguilar-Cordova, J.H. Kim, Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. Cancer Res. 62 (2002) 4968-4976. 

Springer, C. J., and Niculescu-Duvaz, I. Prodrug-activating systems in suicide gene therapy. J. Clin. Invest. 105 1161-1167, 2000. 

Fillat, C., Carrio, M., Cascante, A., and Sangro, B. Suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene/ganciclovir system Fifteen years of application. Curr. Gene. Ther. 3 13-26, 2003. 

Y. Kawashita, A. Ohtsuru, Y. Kaneda, Y. Nagayama, Y. Kawazoe, S. Eguchi, H. Kuroda, H. Fujioka, M. Ito, T. Kanematsu, and S. Yamashita, Regression of hepatocellular carcinoma in vitro and in vivo by radiosensitizing suicide gene therapy under the inducible and spatial control of radiation, Hum. Gene Ther. 10 1509 (1999). 

O. Wildner, J. C. Morris, N. N. Vahanian, H. J. Ford, W. J. Ramsey, and R. M. Blaese, Adenoviral vectors capable of replication improve the efficacy of HSVtk/ GCV suicide gene therapy of cancer, Gene Ther. 6 51 (1999). 

G. Gazit, G. Hung, X. Chen, W. F. Anderson, and A. S. Fee, Use of the glucose starvation-inducible glucose-regulated protein 78 promoter in suicide gene therapy of murine fibrosarcoma, Cancer Res. 59 3100 (1999). 

Steg GR Tahlil O. Aubailly N, et al. Reduction of restenosis after angioplasty in an atheromatous rabbit model by suicide gene therapy, Circulation 1997 96 408-41 I. 

Hattori Y, Maitani Y (2005) Folate-linked nanoparticle-mediated suicide gene therapy in human prostate cancer and nasopharyngeal cancer with herpes simplex virus thymidine kinase. Cancer Gene Ther 12 796-809... 

Reszka RC, Jacobs A, Voges J. Liposome-mediated suicide gene therapy in humans. Methods Enzymol 2005 391 200-208. 

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