Fungi Aspergillus

Delayed action cytotoxins that inhibit the synthesis of nucleic acids. They are obtained from various molds/fungi (Aspergillus flavus, Aspergillus parasiticus). They are colorless to pale-yellow crystalline materials melting above 450°F. The "B" toxins fluoresce blue in the presence of UV light while the "G" toxins fluoresce green. They are only slightly soluble in water, but are soluble in methanol, acetone, and chloroform. Aqueous solutions are "probably stable" and "probably tolerant" to chlorine at purification concentrations. 

Weeks et al. 1979) or DNA damage (Nakamura et al. 1987) following hexachloroethane treatment. Similar results were reported for eukaryotic cells. Hexachloroethane did not cause gene mutation in cells harvested from the stationary growth phase (Bronzetti et al. 1989) or DNA damage in yeast (Saccharomyces cerevisiae) (Simmon and Kauhanen 1978), chromosomal aberrations in fungi (Aspergillus nidulans) (Crebelli et al. 

Mukherjee I, Mittal A (2007) Dissipation of /i-cyfluthrin by two fungi Aspergillus nidulans var dentatus and Sepedonium maheswarium. Toxicol Environ Chem 89 319-326... 

Filamentous fungi Aspergillus nidulans, Aspergillus niger Secretion of large quantities into growth media Genetics not well characterized... 

Amphotericin B is used to treat systemic disseminated fungal infections caused by Candida spp., Cryptococcus neoformans, and the invasive dimorphic fungi Aspergillus spp., Histoplasma capsulatum, Coccidioides immi-tis, Blastomyces dermatitidis, and Sporothrix schenckii). Intravenous amphotericin B remains the treatment of choice for serious invasive fungal infections unresponsive to other agents. 

The major fungal opportunistic pathogens that affect immunocompromised hosts are the yeasts Candida and Cryptococcus, with the filamentous fungi Aspergillus and Fusarium and the dimorphic fungus Histoplasma also causing potentially fatal infections.4 Candida albicans... 

Antimicrobial agent and suspect animal carcinogen Patulin. Isolated from a number of fungi, Aspergillus clavatus, etc. 

Newly synthesized compounds 22, 23, 25c-e, 26d and 29e were screened for their antifungal activity against two species of fungi, Aspergillus ochraceus... 

Several decades ago, the earliest genetic work in molybdenum enzymes identified mutants of two fungi, Aspergillus nidulans (125) and Neurospora crassa (126) that lacked all molybdenum enzyme activities, specifically, nitrate reductase, XDH, and aldehyde oxidase. The mutant N. crassa produces an... 

The second important application of immobilized enzymes is the hydrolysis of lactose to glucose and galactose in milk and milk products by lactase (Sprossler and Plainer 1983). Several lactase sources are available from yeast, Saccharomyces lactis and S. fragilis, or from fungi, Aspergillus oryzae or A. niger. The enzymes vary in their optimum pH and optimum temperature, as well as other conditions. 

Eukaryotic organisms Fungi Aspergillus nidulans Gene mutation No data Crebelli et al. 1986... 

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