Formulation parameters

In addition to the formulation parameters mentioned above, selection of the base used for catalysis has strong implications. Bases commonly used are sodium hydroxide, potassium hydroxide, lithium oxide, calcium hydroxide, barium hy-... 

In addition to the properties noted above, the formulation parameter in iPP-E-plastomer blends have a profound influence on the dynamic loading (e.g., vibration) performance. The load limits of the blend for applications in which dynamic stresses are predominant were studied by using the hysteresis measurement method. However, their technical application requires knowledge of critical load values. 

The initial stage of drug release from the formulation, both in terms of the amount and the rate of release, may exercise considerable influence at the clinical response level. A close consideration of the formulation parameters of any chemical is therefore essential during the development of any new drug, and, indeed, there are examples where formulations of established drugs also appear to require additional investigation. 

Simulations of the effect of paint formulation parameters on the antifouling paint behaviour... 

In Kiil et al. (2002a), the effects of seawater parameters and paint formulation parameters on the paint behaviour are simulated and discussed. As an example of the use of the mathematical model, the effect of CU2O particle size is reviewed here. All present self-polishing antifouling paints use the soluble... 

An FDA interpretation of IVIVC has been cited as To show a relationship between two parameters. Typically relationship is sought between in vitro dissolution rate and in vivo input rate. This initial relationship may be expanded to critical formulation parameters and in vivo input rate (22). 

The phenyl modified polymers possess the optimum combination of high temperature and elastomeric properties and were used in the study of formulation parameters These variables can have an important effect on the thermal stability and property profile of vulcanized systems For example, the use of reinforcing silicas, peroxide content, and oxidative stabilizers have been shown to be important ( 3, 10, in However, polymer-silica interactions had the most pronounced effect on retaining properties during high temperature aging studies ... 

Optimization of Formulation Parameters and Drug Absorption Enhancement Strategies... 

Scholz M, Lin JE, Lee VE1, Keipert S. Pilocarpine permeability across ocular tissues and cell cultures Influence of formulation parameters. J Ocul Pharmacol Ther 18 455-468 (2002). 

Additional trials developed an expanded operational range for the 5% active preblend formulation. Parameters are identified in Table 11. 

Capan, Y., Woo, B.H., Gebrekidan, S., Ahmed, S., and Deluca, P.P. (1999). Influence of formulation parameters on the characteristics of poly(D,L-lactide-co-glycolide) microspheres containing poly(L- lysine) complexed plasmid DNA. J. Control. Release, 60, 279-286. 

Domingo et al. evaluated immobilization of trichloroethylene-degrading Burkholderia cepacia bacteria using hydrophilic polyurethane foam. The influences of several foam formulation parameters upon cell retention were examined. Surfactant type was a major determinant of retention a lecithin-based compound retained more cells than Pluronic- or silicone-based surfactants. 

Touitou, E., and M. Donbrow. 1983. Promoted rectal absorption of insulin Formulative parameters involved in the absorption from hydrophilic bases. Int J Pharm 15 13. 

Other formulation parameters that may be used to modulate the release include the ratio (relative concentrations) of polymers in the case of incorporation of a mix of two or more polymers as primary coating material, the properties of the core material, and the amount of plasticizers used, which affects the strength of the coat. Plasticizers with low water solubility such as dibutyl sebacate, diethyl phthalate, tri-acetin, triethyl citrate, and acetylated monoglyceride result in delaying... 

The study was designed to evaluate a number of vinyl formulation parameters, varying the plasticizers, resins, antimicrobials, and other additives to find clues as to which films would be most resistant to degradation, before and after weathering. The first part of this paper... 

The following section offers a brief description of how certain additives and formulation parameters are used to control the characteristics of adhesive systems. The roles of specific additives are defined in Chaps. 6 through 10. 

TABLE 3.8 Effect of Various Formulation Parameters on the Flexibility of an Epoxy Adhesive... 

Neradovic, D.,Soga, O., Van Nostrum, C. F., and Hennink,W. E. (2004),The effect of the processing and formulation parameters on the size of nanoparticles based on block copolymers of poly(ethylene glycol) and poly(AMsopropylacrylamide) with and without hydrolytically sensitive groups, Biomaterials, 25(12), 2409-2418. 

Fatouros, A. Sjostrom, B. Recombinant factor VIII SQ—The influence of formulation parameters on structure and surface adsorption. Int. J. Pharm. 2000, 194, 69-79. 

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