Forensic science applications

LC-GC, therefore, shows promise for forensic science applications, reducing sample handling and preparation steps by essentially using an on-line LC column in place of one or more extraction steps. This is followed by a traditional high resolution GC analysis. The methods described here for pesticides and hormones could be readily adapted to a variety of analyses, especially those involving fatty matrices. Such as tissues, food or blood. 

J.C. Lindon, Forensic Science, Applications of IR spectroscopy, in Encyclopedia of Spectroscopy and Spectrometry, Academic Press, San Diego 2000,... 

Other modes, such as chiral chromatography, also exist, but find very little, if any, application in forensic science applications. Should you wish to know more about any of these modes, please see the Further Reading section at the end of this chapter. 

Pitts SJ and Kratochvil B (1991) Statistical discrimination of flat glass fragments by instrumental neutron activation analysis methods for forensic science applications. Journal of Forensic Sciences 36 122-137. 

Tebbett IR (1991) Chromatographic analysis of inks for forensic science applications. Forensic Science Review 3(2) 71-82. 

In another forensic science application, electrospray LC-MS was used to determine elevated levels of insulin-like growth factor 1 (IGF-1) in serum as an indication of growth hormone (GH, somatotropin) abuse in racehorses. Structural identity of IGF-1 was confirmed by LC-MS and LC-MS/MS characterization of the endoproteinase Asp-N digestion product. 

Brettell, Thomas A., John M. Butler, and Jose R. Almi-rall. Forensic Science. Analytical Chemistry 79, no. 12 (2007) 4365-4384. A review of forensic science applications used in common disciplines. 

There are many types of ionization modes and mass separation filters, the discussion of which is beyond the scope of this book. In forensic science applications, the most common design is an electron impact ionization/quadrupole mass filter (Figure 5.62) interfaced to a capillary GC. The small flows of the capillary column, on the order of 1 mL/minute or less, are managed by a simple vacuum system, allowing for a direct insertion of the column into the ionization region. Ionization and fragmentation are achieved by the collisions between... 

Suzuki, E. M., and G. WR. "Forensic Science Applications of Diffuse Reflectance Infrared Spectroscopy (DRIFTS) L" Journal cf Forensic Sciences 31 (19%), 931-95Z... 

Gas Chromatography/Mass Spectrometry FORENSIC SCIENCE APPLICATIONS OF PYROLYSIS GAS CHROMATOGRAPHY... 

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