Forensic science applications explosives analysis

During the last decade, capillary electrophoresis (CE) has developed into a widely applied method for the analysis of pharmaceuticals (both for the evaluation of pharmaceutical formulations and metabolites). These applications established the basis for introducing CE into the forensic held also. Today, capillary electrophoresis can be applied to a number of analytical problems in forensic science, including the analysis of gunshot residues, explosives, inks, dusts, soils, and, of course, illicit drugs, diverse toxicants, DNA hngerprinting, protein analysis, and so forth (for reviews, see Refs. 1 and 2). 

The aforementioned applications of GC have been from several major areas of forensic science, specifically drug analysis and toxicology and other areas of trace evidence, such as pyrolysis, explosives, and the detection of accelerants. There are, however, a few other forensic analyses by GC that have been reported. 

Forensic science encompasses a number of different fields of science. In this book, we are explaining the theories associated with high performance liquid chromatography, the different forms that it may take, and its use in some forensic applications. In this chapter, we will examine applications of HPLC in drug analysis, toxicology, analysis of explosives, analysis of coloured materials, and environmental science. 

Xu, X., et al. (2004) Trace analysis of peroxide explosives by high performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry (HPLC-APCI-MS/MS) for forensic applications. Journcd of Forensic Sciences, 49,1230-1236. 

---