Simulant , food

An extractive study of one can enamel in the presence of food-simulating solvents to determine how gamma radiation from a cobalt-60 source altered the nature and amount of extractives of this enamel. 

The migration of package ingredients directly into a food product is often difficult to analyze instrumentally because of interference from food ingredients. Some of these analyses have been made, but it is generally preferable to use food simulating solvents listed in FDA regulations and to carry out extraction tests under the conditions described. 

Tests have been conducted with Monsanto high barrier nitrile resins using the common food simulating solvents (Table X) plus some typical beverages. Conditioning times and temperatures were based on applicable FDA regulations and guidelines (16). 

On-line NPLC-GC-FID and/or FUR analysis has been used in discriminating between paraffin waxes and paraffin oils present in, or migrating between, food packaging and food simulants FID was used for quantitation [967]. In a typical application, online coupled LC-GC-F1D has also been used for the analysis of food contamination by mineral oil from printed cardboard [968]. The technique has revealed that many foods are contaminated with mineral oil products. Grob et al. [969] have determined mineral oil in canned food by on-line LC-LC-GC-F1D. DEHP was determined in salad oil by means of conventional LC-GC [970]. HPLC-GC-MS/MS (ion trap) can serve highly useful purposes in areas of applications such as impurity... 

Table 6 Phosphites and Phosphonites. (It should be noted that the phosphite and phosphonite classes of stabiliser are particularly reactive and can be prone to decomposition in extraction solvents and food simulants)... 

Determination of ethylene glycol and diethylene glycol in food simulants... 

Part 21 Determination of ethylenediamine and hexamethylenediamine in food simulants Derivitization of the free amine using ethyl chloroformate followed by GC with flame ionisation detection... 

Part 23 Determination of formaldehyde and hexamethylenetetramine (HMTA) in food simulants In the case of HMTA, it is treated with acid and heated to release formaldehyde. Formaldehyde in simulant is determined colorimetrically by reaction with chromotropic add in the presence of sulfuric acid... 

Part 24 Determination of maleic acid and maleic anhydride in food simulants Ion pair HPLC of maleic acid with cetyl trimethyl ammonium chloride and UV detection (245 nm) with citraconic acid as internal standard... 

Part 25 Determination of 4-methyl-pentene in food simulants Headspace GC with cyclohexane as internal standard... 

Part 26 Determination of 1-octene and tetrahydrofuran in food simulants Headspace GC of the food simulant. Iso-octane internal standard for 1-octene and tetrahydropyran internal standard for tetrahydrofuran determinations... 

Part 27 Determination of 2,4,6-triamino-1,3,5-triazine in food simulants Aqueous simulants — HPLC with UV detection 230 nm. Olive oil extracted with water/isopropanol... 

Part 28 Determination of 1,1,1-trimethylolpropane (TMP) in food simulants Aqueous food simulants are saturated with potassium carbonate and extracted with ethanol/ethyl acetate. After evaporation of solvent the extracted TMP is silyated with trimethylsilylimidazole in pyridine and determined by GC with flame ionisation detection... 

McNeal T, Brumley WC, Breder C, et al. 1979. Gas-solid chromatographic-mass spectrometric confirmation of low levels of acrylonitrile after distillation from food-simulating solvents. J Assoc Off Anal Chem 62 41-46. 

DETERMINATION OF BADGE, BFDGE AND NOGE IN FOODS, FOOD SIMULANTS AND COATINGS... 

The Scientific Committee for Food (SCF) lays down for toxicological evaluation of food contact substances three levels of toxicological tests dependent on the amount of migration (mg/kg food simulant) Level 1 < 0.05 level 2 0.05-5 level 3 >5. 

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