Fluorescence molecular probes

Liu J, Bhalgat M, Zhang C et al (1999) Fluorescent molecular probes V a sensitive caspase-3 substrate for fluorometric assays. Bioorg Med Chem Letts 9 3231-3236... 

Pantoja, S., Lee, C., Marecek, J. F., and Palenik, B. P. (1993). Synthesis and use of fluorescent molecular probes for measuring cell-surface enzymatic oxidation of amino acids and amines in seawater. Anal. Biochem. 211, 210-218. 

A wide variety of fluorescent molecular probes have been demonstrated to be suitable for excitation by the He-Cd laser 4-bromomethyl-7-methoxycoumarln has been employed for the detection of carboxylic and phosphoric acids (44,55), 7-chlorocarbonyl-methoxy-4-methylcoumarln for hydroxyl compounds (42), 7-lsothlocya-nato-4-methylcoumarln for amines and amino acids (55), 7-dlazo-4-methyl-coumarln for a variety of aromatic compounds (55), and terbium chelate molecules with long fluorescence lifetimes ( 1 ms) for protein analysis (56). In this study, we examined the utility of l-dlmethylamlnonaphthalene-5-sulfonyl chloride (dansyl chloride) as a sensitive and selective reagent for the determination of biogenic amines and amino acids. 

Metal ion interaction with a novel anthracene pendant-armed fluorescent molecular probe. Synthesis, characterization, and fluorescence studies. Inorg. Chem. Acta, 360, pp. 2734-2743, ISSN 0020-1693... 

Kitts, C. C., and Vanden Bout, D. A. 2009. Near-field scanning optical microscopy measurements of fluorescent molecular probes binding to insuhn amyloid fibrils,/P/rys Chem B 113,12090-12095. 

Cyanines are a class of conjugate organic dyes. Fluorescence of the trans species is in competition with a photoisomerisation towards the cis species, which represents a technological obstacle to their use as fluorescent molecular probes in imagery [85],... 

See also Biochemical Applications of Fluorescence Spectroscopy Fluorescence Microscopy, Applications Fluorescent Molecular Probes Fluorescence Polarization and Anisotropy Inorganic Condensed Matter, Applications of Luminescence Spectroscopy UV-Visible Absorption and Fluorescence Spectrometers X-Ray Fluorescence Spectrometers X-Ray Fluorescence Spectroscopy, Applications. 

See also ATR and Reflectance IR Spectroscopy, Applications Eiiipsometry Fluorescent Molecular Probes Inorganic Condensed Matter, Applications of Luminescence Spectroscopy Organic Chemistry Applications of Fluorescence Spectroscopy Surface Plasmon Resonance, Applications Surface Plasmon Resonance, Instrumentation. 

See also Fluorescent Molecular Probes Geology and Mineralogy, Applications of Atomic Spectroscopy Inorganic Compounds and Minerals Studied... 

Plate 20 An example of a fluorescent molecular probe, Endogenous alkaline phosphatase activity in the zebraflsh brain was localized with an endogenous phosphatase detection kit. Enzymatic cleavage of the phosphatase substrate yields a bright yellow-green fluorescent precipitate at the site of enzyme activity. See Fluorescent Molecular Probes. Reproduced with permission from Greg Cox, Molecular Probes, Inc. 

Plate 21 A fluorescent molecular probe. Fixed and permeabilized osteosarcoma cells were simultaneously stained with the fluorescent lectins, Alexa 488 concanavalin A (Con A) and Alexa 594 wheat germ agglutinin (WGA). Con A selectively binds a-mannopyranosyl and a-glucopyranosyl residues, whereas WGA selectively binds sialic acid counterstained with blue-fluorescent Hoechst 33342 nucleic acid stain. See Fluorescent Molecular Probes, Inc. 

Bakeev, K. N. MacKnight, W. J. Fluorescent molecular probe technique for assessing the interaction between sulfonated polystyrene and poly... 

Martin, V.V., Alferiev, I.S., Weis, A.L. AmpUfled fluorescent molecular probes based on 1,3,5,7-tetrasubstituted adamantane. Tetrahedron Lett 1999, 40 223-226. 

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