Fisher, Scott

Salmine Sulfate. A protamine found in the sperm of salmon. Contains arginine, proline, serine, glycine, valine, leucine, alanine, threonine, isoleucine, lysine, histidine, aspartic and glutamic acids. Mol wt 6000 to 7000. N about 25%. Prepn and properties Fisher, Scott, J. Pharmacol. Exp. Ther. 58, 78 (1936) Felix. Am. Sci. 43, 431 (1955) Callanan et al., J. Biol Chem 229, 279 (1957) Carroll er al, ibid. 234, 2314 (1959). Separation of components and amino add sequence of major component Ando, Watanabe, Ini. J, Protein Res. 1, 221 (1969). 

Scott, K. G., Overstreet, R., Jacobson, L., Hamilton, J. G., Fisher, H., Crowley, J., Chaikoff, I. L., Entenman, C., Fishler, M., Barger, A. J. AND Loomis, F. (1947). The Metabolism of Carrier-Free Fission Products in the Rat, Report No. MDDC-1275 (National Technical Information Service, Springfield, Virginia). 

While sulfur-free amino acids are broken down to amines via decarboxylation, the sulfur-containing amino acids such as cysteine can undergo more complex reactions. Fisher and Scott suggest that, because cysteine produces a powerful reducing aminoketone, hydrogen sulfide could be produced by reducing mercaptoacetaldehyde or cysteine.2... 

Reprinted with permission from Food Flavours Biology and Chemistry, C. Fisher and T. R. Scott, 1997 Royal Society of Chemistry)... 

R.J. Hicks, D. Rischin, R. Fisher, D. Binns, A.M. Scott, L.J. Peters, Utility of FMISO PET in advanced head and neck cancer treated with chemoradiation incorporating a hypoxia-targeting chemotherapy agent, Eur. J. Nucl. Med. Mol. Imaging 32(12) (2005) 1384-1391. 

Recrystallized Gold Label benzophenone (99+%) was obtained from Aldrich Chemical. SCF grade carbon dioxide was received from Scott Specialty Gases and 2-propanol (certified ACS grade) was obtained from Fisher Chemical. Both the C02 and the 2-propanol were used as received. 

Bulk Density. Bulk density determinations were made using a Scott paint volumeter (Fisher Scientific Co.) with a 1 in brass receiver to collect the sample. 

H.A. Gardner Laboratory, Inc., Bethesda,. Md (I95O), 402-03 (Description of Scott s Volumeter, manufd by Fisher Scientific Co it serves for detn of volume of powdered materials) J) A. M. Cummings, USP 2577110(1951) CA 46,... 

Keilin and Mann (1939, 1940a) first noted that zinc is a constituent of carbonic anhydrase. Leiner and Leiner (1940) and Hove, Elvehjem, and Hart (1940) corroborated these findings. Day and Franklin (1946) found zinc in carbonic anhydrase extracted from plants. The figures on the percentage zinc content vary. Keilin and Mann (1940a) found 0.33 %, Hove, Elvehjem, and Hart (1940) 0.318% for enzyme preparations of comparable purity, as judged by their activity. Scott and Mendive (1941b) reported 0.15% of zinc for their purified and 0.2% to 0.23% for their crystalline preparations (Scott and Fisher, 1942). 

Hayes and V elick (1954) Vallee and Hoch (1955) Scott and Fisher (1942) Keilin and Mann (1940) Green and Neurath (1954) Vallee and Neurath (1954)... 

Although few animal species are shared between vents and seeps, dominant species of both communities (bathymodiolid mussels, vesicomyid clams and vestimentiferan worms) are phylogenetically related and share similar physiology and anatomy (Scott Fisher, 1995 Peek etal., 1997 Tunnicliffe etal.,... 

Scott, K.M. and Fisher, C.R. (1995) Physiological ecology of sulfide metabolism in hydrothermal vent and cold seep vesicomyid clams and vestimentiferan tube worms. American Zoologist, 35, 102-111. 

Jensen and DeLawder9s purified commercial insulin by adsorption on activated carbon followed by elution with 90% phenol. The phenol eluate was diluted with water and the insulin that flocked out was washed with absolute alcohol and ether. Insulin thus prepared has an activity about equal to that of crystalline insulin. The activity was not further increased by a subsequent adsorption and elution. This finding is supported by data of Fisher and Scott,96 and is in contrast to an observation by Dingemanse97 that a product of greater activity than crystalline insulin can be prepared by this procedure. 

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