Fast Atom Bombardment FAB and Liquid-matrix Secondary Ion Mass Spectrometry LSIMS

Fast Atom Bombardment (FAB) and Liquid-matrix Secondary ion Mass Spectrometry (LSiMS) 

Although FAB is used less frequently today, it is still a very valuable method. It is widely assumed that FAB mass spectra reveal solution-phase chemistry quite accurately, while this statement is still controversial in ESI/MS vide infra). 

as the mildest ionization method, is able to transfer even relatively weakly bonded complex ions from the liquid to the gas phase, which makes it the most 

Representative examples of ESI measurements of CyD inclusion complexes selected from the literature (starting from 1996) are collected in Table 10.2.1. 

It must be repeated again that the presence of a peak in the MS spectrum with an m/z value corresponding to the expected cationized or anionized complex ion does not necessarily mean that we are observing an inclusion complex that is also present in solution. 

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