Extensor digitorum longus muscle

Basson (1978), Basson Carlson (1980) described myotoxicity after single and repeated injections of mepivacaine in the rat. Young rats received single or repeated injections of 2% mepivacaine into the tibialis anterior or extensor digitorum longus muscles. Repeated injections consisted of 6 injections of the anesthetic (100 il per injection into the tibialis anterior) on different schedules, at intervals of 21/2 hours, 24 hours, or 4 days. The muscles were examined histologically for evidence of myotoxicity at 0 to 7 and 20 days after the last injection. Single injections showed that mepivacaine is a myotoxic... 

Adler, M., MacDonald, D.A., Sellin, L.C., Parker, G.W. (1996). Effect of 3,4-diaminopyridine on rat extensor digitorum longus muscle paralyzed by local injection of botulinum neurotoxin. 

Locomotion is produced by muscular shortening (see Section 4.4.2). The intrinsic speed of muscular sarcomere shortening for mammals has been found to depend on body mass (Figure 7.4.18). Equations relate mass and maximum shortening speed of the extensor digitorum longus muscle (McMahon, 1984) ... 

Values are expressed as mean (SEM) of 4-6 muscles. EDL, extensor digitorum longus SOD, superoxide dismutase. 

It is well established that AChE exists in nerves and muscles in a range of globular and asymmetric molecular forms. A wide variety of sedimentation profiles have been established for AChE moleeular forms in different mammalian muscles (Massoulie and Bon, 1982). The variations seen in the ratios of these moleeular forms between different muscles are wide and eomplex. Qualitative and quantitative variations exist among different species, as well as young versus adult (Barnard et al, 1984). In the rat extensor digitorum longus (EDL, a fast twitch muscle), the... 

G7. Goldspink, D. F., Harris, J. B., Park, D. C., and Pennington, R. J., Quantitative enzyme studies in extensor digitorum longus and soleus muscles of rats. Enzymol. Biol. Clin. 11, 481-490 (1970). 

Other mammalian skeletal muscle preparations which have been used for in vitro studies are the extensor digitorum longus of the rat (Zierler, 1959a,b) and fibers of adductor muscles (Beatty et al., 1960), or teased fibers of sternomastoid, sternohyoid, or scalenus muscles of the rat (Hall, 1960). The suitability of these in vitro preparations for studying regulation of glucose uptake has yet to be established. 

We report here an account of our preliminar experiments, using the fast-twitch extensor digitorum longus (hereafter called EDL) muscle and its nerve supply. 

The major muscle of ankle dorsiflexion is the tibialis anterior, assisted by the extensor digitorum longus, the extensor hallucis longus, and the peroneus tertius. The major muscles of ankle plantar flexion are the gastrocnemius and soleus, assisted by the plantaris, tibialis... 

The anterior muscles of the lower leg lie in a more medial position. From medial to lateral, they are the tibialis anterior, the extensor hallucis longus and the extensor digitorum longus (Fig. 15.1). The tibialis anterior is a strong muscle which arises just lateral to the anterior border of the superior two thirds of the tibia (Fig. 15.2a). It has a circumpennate structure with an internal aponeurosis oriented in a coronal oblique plane. The aponeurosis continues downward in a strong oval tendon which courses along the anterior edge of the tibia and the anterior aspect of the ankle joint. The anterior tibialis muscle is the stron-... 

Muscle hernias are focal protrusions of muscle tissue through fascial defects. In the lower leg, herniation of muscle is most commonly observed in the middle and lower thirds affecting the tibialis anterior muscle, although involvement of the extensor digitorum longus, peroneal muscles and the lateral head of the gastrocnemius have also been reported (Mellado and Perez del Palomar 1999). The area overlying the anterior intermuscular septum. 

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