Tibialis anterior muscle

The first peculiarity of muscle spectra is the possibility to differentiate two lipid compartments. Furthermore, the characteristics of the lipid signals depend on the chosen particular muscle and its orientation with respect to the magnetic field. Figure 15 shows a typical spectrum of the tibialis anterior muscle (TA) in comparison with a spectrum from the fatty bone marrow of... 

Fig. 30. Thirteen-year-old boy with desmin storage myopathy, (a) The T weighted image shows an atrophy of the tibialis anterior muscle (with the volume element indicated) and a fatty degeneration of the soleus muscle (arrow), (b) The spectrum from the tibialis anterior muscle shows prominent EMCL. TMA is reduced as indicated in the area of the 5-fold magnification.

Sacco, P., Jones, D.A., Dick, J.R., and Vrbova, G., 1992, Contractile properties and susceptibility to exercise-induced damage of normal and mdx mouse tibialis anterior muscle, Clin Sci (Lond), 82, pp 227-236. 

Simoneau, J-A., and D. Pette (1998). Species-specific effects of chronic stimulation upon tibialis anterior muscle in mouse, rat, guinea pig, and rabbit. Pflugers Arch. 412 86-92. 

Twitches of the right tibialis anterior muscle are elicited at 0.15 Hz via the peroneal branch of the right... 

Driessen JJ, Vree TB, van Egmond J, Booij LH, Crul JF. Interaction of midazolam with two non-depolarizing neuromuscular blocking drugs in the rat in vivo sciatic nerve-tibialis anterior muscle preparation. Br J Anaesth 1985 57(ll) 1089-94. 

Fig. 3 Distribution of injected DNA vaccines. A rhodamine-conjugated DNA vaccine was injected into a tibialis anterior muscle of a mouse shown by light (panel A) and fluorescence (panel C) microscopy ( 5x magnification). A longitudinal section of the muscle is shown in panel B ( 250x magnification), demonstrating the presence of DNA in cells between the muscle fibers. Panel C shows the phagosomal location of the plasmid DNA (in red) within the cells isolated from the injected tissues ( 2500x magnification). (See Color Plate p. xxii).

Figure 10 Time-course of gene expression in muscles C57B1/6 mice (6-8 week old females) were injected with 5pg of pCMV-luc alone or formulated with SP1017 in tibialis anterior muscles. The muscles were harvested from day 1 to day 35 after injection and extracted with a lysis buffer to measure the ludferase activity. (From Ref. 89.)...

Measurements of lipids in muscle and bone have also been made. Ye et al. found significantly higher levels of intramyocellular lipids (IMCL) in the tibialis anterior muscle of obese mice (Lep° /Lep° ) compared to control mice (Lep° / + heterozygous). Whereas, Xiao et al. have quantified the apparent diffusion coefficients (ADC) for extramyocellular lipids (EMCL) and IMCL in Sprague-Dawley rats along the direction perpendicular to muscle fibre orientation. The ADC for EMCL and IMCL were 13.8 0.9 X 10 and 4.6 0.7 x 10 mm s respectively. In bone. 

A muscle hernia is a protrusion of muscle through a defect in the epimysium. There is often a previous history of trauma or surgery. Patients present with a palpable lump that may become more apparent and/or painful on standing or exercise. The commonest affected site is the lower leg, particularly the tibialis anterior muscle which has an intrinsic weakness in its overlying fascia due to penetrating... 

Fig. 8 Effect of P85 formulation on the expression of luciferase after i.m. administration of the plasmid DNA in mice. Bilateral tibialis anterior muscles of Balb/c, C57B1/6 or athymic nu/nu mice were injected with 5 xg of gWiz Luc formulated with 0.3% w/v P85 or the plasmid DNA alone...

Period leg movements during sleep Although there have been prior reports of mirtazapine being associated with RLS [77, 78, 79 ], there have been no prior reports of period leg movements during sleep (PLMS). This diagnosis requires polysomnography with recording of tibialis anterior muscle activity. Most patients with PLMS do not have... 

Dynamic scanning during passive extension-flexion movements of either the greater or the lesser toes in a group maybe helpful to distinguish them. Longitudinal planes may show the circumpennate appearance of the tibialis anterior muscle. Deep to the anterior muscles, US is able to depict the interosseous membrane as a thin, continuous line joining the tibia and the fibula (Fig. 15.3a) (Durkee et al. 2003). 

Muscle hernias are focal protrusions of muscle tissue through fascial defects. In the lower leg, herniation of muscle is most commonly observed in the middle and lower thirds affecting the tibialis anterior muscle, although involvement of the extensor digitorum longus, peroneal muscles and the lateral head of the gastrocnemius have also been reported (Mellado and Perez del Palomar 1999). The area overlying the anterior intermuscular septum. 

Fig. 15.15a-c. Muscle hernia, a-c Transverse 12-5 MHz US images obtained with different degrees of probe pressure over the defect show disruption of the tibialis anterior muscle fascia (open arrowhead) from the tibia (T) and subsequent muscle herniation within the subcutaneous tissue asterisks). Note progressive reduction of the herniation with graded compression. White arrowhead indicates the internal aponeurosis of the tibialis anterior muscle... 

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