Ethylene-diaminetetraacetic acid

Commercial Hquid sodium alumiaates are normally analyzed for total alumiaa and for sodium oxide by titration with ethylene diaminetetraacetic acid [60-00-4] (EDTA) or hydrochloric acid. Further analysis iacludes the determiaation of soluble alumiaa, soluble siHca, total iasoluble material, sodium oxide content, and carbon dioxide. Aluminum and sodium can also be determiaed by emission spectroscopy. The total iasoluble material is determiaed by weighing the ignited residue after extraction of the soluble material with sodium hydroxide. The sodium oxide content is determiaed ia a flame photometer by comparison to proper standards. Carbon dioxide is usually determiaed by the amount evolved, as ia the Underwood method. 

Metal Deactivation. Compounds capable of forming coordination complexes with metal ions are needed for this purpose. A chelating agent such as ethylene-diaminetetraacetic acid (EDTA) is a good example. 

Under nitrogen, 2,2 -bipyridine (0.322 g, 2.07 mmol) was added to a mixture of Ni(COD)2 (0.570 g, 2.07 mmol) in anhydrous DMF (18 mL) and the mixture was stirred at room temperature for 1 h. Then 95 (0.510 g, 1.60 mmol) was added and the reaction mixture was stirred at 60-70°C for 28 h. After cooling to room temperature, HC1 (100 mL, 2 M) was added and the mixture was stirred overnight. After filtration, the solid was washed with a mixture of MeOH (60 mL) and concentrated HC1 (10 mL), a warm aqueous solution of ethylene-diaminetetraacetic acid (EDTA) (pH 9, then pH 3), dilute ammonia, water, and MeOH repeatedly and dried under vacuum for 20 h at 80°C. Polymer 96 was obtained in 100% yield (0.261 g). Light scattering gave Mw = 5400. 

The effect of Ca was assayed by viscosimetry in reaction mixtures containing 0.187 % pectin, buffered at pH 8.0, and ethylene diaminetetraacetic acid (EDTA) (0.005 M) or CaClj (0-0.02 M). 

A monodentate palladium(II) complex trans-[Pd(py)2(H202)]2+ hydrolyzes Met-Aa amide bonds with a rate comparable with that promoted by [Pd(H20)3(0H)]+. Unlike Pd(H20)3(0H)]+, //chelated complex containing temed (A,A,AAA -tctramcthylcthylenediamine) hydrolyzes Met-Aa amide bonds with hydrolytic rate controlled by temed release. The action of the other two complexes, c -[Pd(ED-TA)C12] (EDTA = ethylene diaminetetraacetic acid) and cis-1,2-bis(2-formylglycinebenzene-sulfenyl)ethane Pd11 chloride differs from the action of similar complexes of U,v-[Pd(en)Cl2] and cw-[Pd(dtco-3-OH)Cl2] (dtco-3-OH = l,5-dithiacycooctan-3-ol).448... 

Chemicals Ascorbate, Potassium Phosphate, Ethylene DiamineTetraacetic Acid (EDTA), Sodium Ascorbate, H202 Polyvinylpyrrolidone (PVP). 

Krot, N. N., Ermolaev, N. P. and Gellman, A. D. (1962). The behavior of ethylene-diaminetetraacetic acid in acid solutions and its reaction. with uranium (IV), Zh. Neorg. Khirn. 7,2054. 

There have been many studies of the complex formation of plutonium with ethylene-diaminetetraacetic acid (EDTA) and DTPA. Over the range pH 1.0 to 3.0 Pu(III) formed 1 1 complex with EDTA with a stability constant of 1.3 x 1018 (22). At pH 3.3 Pu(IV) reacted with EDTA to form two complexes with Pu EDTA ratios of 1 1 and 1 2 with stability constants of 4.5 x 1012 and 1.6 x 1024, respectively. 

Fig. 14. Structures of some common chelators useful for GFR measurement EDTA, ethylene-diaminetetraacetic acid DTPA, diethylenetriaminepentaacetic acid DOTA, cyclododecane-1,4,7,10-tetraazaacetic acid...

The effects of other contaminants in the feed stream was tested using ammonia and ethylene-diaminetetraacetic acid (EDTA). While ammonia had little effect on the effectiveness, EDTA affected efficiency significantly. When the metals were complexed with EDTA, they broke through almost immediately, making the capacity of the media to remove metals not significant... 

Viro, RJ. (1955) Use of ethylene-diaminetetraacetic acid in soil analysis. Exptl Soil Sri., 79, 459-465. 

EDTA eluent (lm mol L-1) was prepared by dissolving ethylene diaminetetraacetic acid disodium salt in deionised water and adjusting to pH 6.0 with O.lmol L 1 sodium hydroxide. 

The angiotensin I-converting enzyme (ACE), designated peptidyl-dipeptidase A (E.C.3.4.15.1), is identical to the bradykinin-metabolizing enzyme kininase II (38). Its early history and initial characterizations have been reviewed (51-54). It was discovered by Skeggs and co-workers (55), and in their pioneering work they showed it to be inhibited by ethylene-diaminetetraacetic acid (EDTA) (37), to remove a dipeptide from the carboxyl terminus of angiotensin I (then called hypertensin I [56]) and to be activated by sodium chloride (55). The fact that ACE is a Zn2+-contain-ing peptidase was first reported by Das and Sofler in 1975 (57). 

Further work on human serum transferrin by Aasa et al. (1) did not corroborate the earlier work of Davis et al. (32) and showed that there were no differences between the ions in iron complexes of human serum transferrin. Aasa et al. (1) believed that the earlier work of Davis et al. (32) was incorrect in that the competitive experiments with ethylene-diaminetetraacetic acid were not dialyzed sufficiently long for equilibrium to be obtained. 

Photoreductions of free base porphyrins and metal complexes with a variety of reducing agents, including ascorbic acid, glutathione, ethylene-diaminetetraacetic acid (EDTA), and acetoacetate, have been studied mainly from a mechanistic point of view (75MI6). Unstable hydroporphyrins of phlorin type VI are formed, which subsequently isomerize to chlorins, bacteriochlorins, or isobacteriochlorins. 

Rare earths Dowex-50 5% ammonium citrate, pH 3-3.5, or 0.2-0.4 M a-hydroxyisobutyric acid, pH 4.0-4.6, or 0.025 M ethylene-diaminetetraacetic acid (EDTA)... 

Ru(II)tris(bipyridine) [Ru(bpy)3 +] as a photosensitizer, triammonium ethylene-diaminetetraacetic acid [(NH4)3EDTA] as a sacrificial electron donor and the enzyme ferredoxin NADP+ reductase (FDR) [215, 216]. Oxidative electron-transfer quenching of the excited Ru(bpy)3 + yields the A,A -dimethyl-4,4 -bipyridinium radical cation (reduced methylviologen, MV+), which mediates the reduction of NADP+ in the presence of FDR as a biocatalyst (Figure 32A). The quantum efficiency for NADH production corresponds to = 1.9 x 10 . A related system that includes Zn(II)wc50-(A-tetramethylpyridinium)porphyrin (Zn-TMPyP +) as a photosensitizer, mercaptoethanol as a sacrificial donor and lipoamide dehydrogenase (LipDH) as a biocatalyst has been applied for the photochemical reduction of NAD+ to NADH (Figure 32B). 

In 1945 Schwarzenbach published the first of a series of fundamental studies of polyaminopolycarboxylic acids as analytical chelating reagents. Of these, ethylene-diaminetetraacetic acid, usually abbreviated EDTA, has become one of the most important of all the reagents used in titrimetry. Another important contribution made by Schwarzenbach and his coworkers was the development of indicators that respond to changes in metal ion activity. 

One of the best-known chelating agents is ethylene-diaminetetraacetic acid, or EDTA. It contains 32 atoms, six of which can bond to a single metal atom. 

Synonyms calcium disodium edetate calcium disodium ethylenediaminetetraacetate calcium disodium (ethylene-dinitrilo)tetraacetate E385 edathamil calcium disodium edetic acid calcium disodium salt EDTA calcium ethylene-diaminetetraacetic acid calcium disodium chelate [(ethyl-enedinitrilo)tetraacetato]calciate(2-) disodium sodium calciumedetate Nersene CA. 

Either serum or heparinized plasma is used to measure total or free testosterone. Testosterone is subject to a diurnal variation, reaching a peak concentration between 0400 hours and 0800 hours. Therefore, morning specimens are preferred. Specimens are stable for a week (men) or 3 days (women) refrigerated and for up to 1 year frozen at 20 No steroids, thyroid, ACTH, estradiol, or gonadotropin medications should be given for 48 hours before sample collection. Most assays are standardized for serum or heparinized plasma. Other anticoagulants such as ethylene-diaminetetraacetic acid (EDTA) may give different values. In certain RIA assays, presence of EDTA appears to cause a 10% decrease in total testosterone concentrations. ... 

CTA = chromotropic acid DNPH = 2,4-dinitrophenylhydrazine EDTA = ethylene diaminetetraacetic acid FIA = flow injection analysis GC = gas chromatography ... 

Pakalapati, S.N.R., B.N. Popov, and R.E. White. 1996. Anodic oxidation of ethylene-diaminetetraacetic acid on platinum electrode in alkaline medium. J. Electrochem. Soc. 143 1636-1643. 

The total content of calcium and magnesium is determined by titration with chelatone 3 (the double sodium salt of ethylene diaminetetraacetic acid) at pH 10 using Eriochrome Black T as an indicator (from wine-red to blue) [14, 32, 37] ... 

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