Ethyl-2-hydroxypropanoate

The crystal structure of the adduct of titanium tetrachloride and the ester formed from ethyl 2-hydroxypropanoate (ethyl lactate) and acrylic acid has been solved. It is a chelated structure with the oxygen donor atoms being incorporated into the titanium coordination sphere along with the four chloride anions. 

Chemical Designations - Synonyms Ethyl Alpha-hydroxy-propionate Ethyl 2-hydroxypropanoate Ethyl DL-Lactate Lactic Acid Ethyl Ester Chemical Formula CH3CHOHCOOC2H3 Observable Characteristics - Physical State (as shipped) Liquid Color Colorless Odor Mild characteristic. 

ETHYL-2-HYDROXYPROPANOATE (97-64-3) Forms explosive mixture with air (flash point 115°F/46°C cc). Contact with strong oxidizers may cause fire and explosions. Incompatible with nitrates. 

Ethyl-2-hydroxymethyl-1,3-propanediol trimethacrylate. See 1,1,1 Tri methylolpropane trimethacrylate 4-Ethyl-3-hydroxy-1-octyne. See Ethyl octynol Ethyl 2-hydroxypropanoate Ethyl 2-hydroxypropionate Ethyl a-hydroxypropionate Ethyl-S(-)-2-hydroxypropionate. See Ethyl lac tate... 

Ethyl 2-hydroxypropanoate. See Ethyl lactate Ethyl-(S)-2-hydroxypropanoate. See Ethyl-(S)-lactate... 

CAS 97-64-3 EINECS/ELINCS 202-598-0 UN 1192 (DOT) FEMA 2440 Synonyms Ethyl 2-hydroxypropanoate Ethyl 2-hydroxypropionate Ethyl a-hydroxypropionate 2-Hydroxypropionic acid ethyl ester Lactic acid ethyl ester Classification Lactate ester Definition Ethyl ester of lactic acid commercial prod, is a racemic mixt. 

Ethylenediamine Tetracetic Acid T richlorophenoxyacetate Ethyl 2-Hydroxypropanoate Ethyl Lactate... 

S)-2-(Benzyloxy)propanal Propanal, 2- phenylmethoxy)-, (S)- (11) (81445-44-5) (S)-Ethyl hydroxypropanoate (S)-Ethyl lactate Lactic acic, ethyl ester, L- (8) Propanoic acid, 2-hydroxy-, ethyl ester, (S)- (9) (687-47-8) 0-Benzyl-2,2,2-trichloroacetimidate Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester (11) (81927-55-1)... 

Ethyl Lactate Hydroxypropanoic Acid, Ethyl Ester Methyl Methacrylate... 

Ethylbenzene under Benzene and Monosubstituted Benzene Hydrocarbons Ethyl Chloride Chloroethane under Saturated Alkyl Halides Ethyl Lactate Hydroxypropanoic Acid, Ethyl Ester under Esters Ethylene under Alkenes, Cyclic Alkenes, and Dienes... 

Actylol Acytol ethyl a-hydroxypropionate ethyl-2-hydroxy-propanoate ethyl-2-hydroxypropionate ethyl-S-(-)-2-hydr-oxypropionate 2-hydroxypropanoic acid ethyl ester lactic acid ethyl ester propanoic acid 2-hydroxy-ethyl ester Purasolv EL Solactol. 

These reductions follow a similar procedure as for 1-phenylethanone at atmospheric pressure (vide supra). However, they are generally complete in 4 hours at 25 C or 24 hours at 0 °C, except in the case of methyl 3-mcthyl-2-oxobutanoatc which requires 8 days at 25 °C. Slightly better asymmetric inductions may be achieved using boranes with larger steric requirements12, e.g., the reduction of methyl 2-oxopropanoate with the 2-ethyl analog of Alpine-Borane yields methyl (5)-2-hydroxypropanoate with 97 % ee. 

Compound (VIII.98), a folic acid analogue with a y-fluoro substituent in the side-chain was described first by Alekseeva e/ al. [281] and several years later by Bergmann and Chun-Hsu [282]. The synthesis of (VIII.98), as mixture of threo and erythro isomers, was achieved via the Waller method from V-(4-ami-nobenzoyl)-y-fluoroglutamic acid, 2,4,5-triamino-6(lif)-pyrimidinone, and 2,3-dibromopropionaldehyde, but the yield was low (5.6%). y-Fluoroglutamic acid, as a mixture of D- and L-enantiomers, was prepared from diethyl 2-fluoromalonate by condensation with ethyl 2-acetamidoacrylate followed by hydrolysis and decarboxylation in refluxing 12 M HCl, or from ethyl 3-chloro-2-hydroxypropanoate by a sequence consisting of (i) 0-t-butylation with CH2 = C(CH3)2, (ii) condensation with diethyl 2-acetamidomalonate, (hi)... 

Some of substrates required for this study were prepared in mechanochemical conditions ethyl 3-(furan-2-yl)-3-hydroxypropanoate was prepared by Reformatsky reaction (chapter Carbon-Carbon Bond- Forming Reactions), while reduction of 2-acetylbenzofuran 57 was carried out with NaBHj (Scheme 6.20). Reduction of aldehyde 54 in planetary ball mill (agate beaker and balls) afforded alcohol 57 in high yield while the presence of choline chloride gives better yield, reduction of 5-hydroxymethylfurfural 56 without choline chloride was sluggish. 

Methyl ethyl carbinol. See 2-Butanol Methylethylcetoxime. See Methyl ethyl ketoxime 1-Methyl ethylene carbonate. See Propylene carbonate Methyl ethylene glycol. See Propylene glycol Methyl ethylene oxide. See Propylene oxide Methyl ethyl glycol. See Propylene glycol 1-Methylethyl hexandecanoate. See Isopropyl palmitate 1-Methylethyl 2-hydroxypropanoate. See Isopropyl lactate 4,4 -(1-Methylethylidene) biscyclohexanol. See Bisphenol A, hydrogenated 4,4 -(1-Methylethylidene) bisphenol. See Bisphenol A 2,2 -((1-Methylethylidene) bis (4,1-phenyleneoxymethylene)) bisoxirane. See Bisphenol A diglycidyl ether... 

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