Formic ethyl ester

Chemical Designations - Synonyms Ethyl Formic Ester Ethyl Methanoate Formic Acid, Ethyl Ester Formic Ether Chemical Formula HCOOC Hj. 

Synonyms AI3-00407 Areginal BRN 0906769 Caswell No. 443A EINECS 203-721-0 EPA pesticide chemical code 043102 Ethyl formic ester Ethyl methanoate FEMA No. 2434 Formic acid, ethyl ester Formic ether NSC 406578 UN 1190. 

Synonyms Formic ether ethyl methanoate ethyl formic ester... 

ETHYL FORMATE Ethyl Formic Ester, Ethyl Methanoate, Formic Add, ethyl ester Flammable Liquid, II 2 3 0... 

SYNS AETHYLFORMIAT (GERMAN) AREGINAL ETHYLE (FORMIATE dO (FRENCH) ETHYLFORMIAAT (DUTCH) ETHYL FORMIC ESTER ETHYL METHANOATE ETILE (FORMIATO di) (ITALIAN) FEMA No. 2434 FORMIC ACID, ETHYL ESTER FORMIC ETHER MROWCZAN ETYLU (POLISH)... 

ETHYL FORMIC ESTER (109-94-4) Forms explosive mixture with air (flash point —29°F/-34°C). Violent reaction with strong oxidizers, strong alkalis. Incompatible with nitrates, strong acids. Flow or agitation of substance may generate electrostatic charges due to low conductivity. 

Synonyms cas 109-94-4 areginal ethyl formic ester ethyl methanoate formic acid, ethylester ... 

CAS 109-94-4 EINECS/ELINCS 203-721-0 UN 1190 (DOT) FEMA 2434 Synonyms Ethyl formic ester Ethyl methanoate Formic acid ethyl ester Formic ether... 

Ethylformic acid. See Propionic acid Ethyl formic ester. See Ethyl formate Ethyl fumarate... 

Ethylene Glycol Ethyl Formic Ester Ethyl Formate... 

Ethyl Formate — (i) Chemical Designations — Synonyms Ethyl Formic Ester Ethyl Methanoate Formic Acid, Ethyl Ester Formic Ether Chemical Formula HCOOCjHj (ii) Observable Characteristics — Physical State (as shipped) Liquid Color Colorless Odor Characteristic pleasant aromatic (iii) Physical and Chemical Properties — Physical State at IS °C and 1 atm Liquid Molecular Weight 74,1 Boiling Point at 1 atm 129.6, 54.2, 327.4 Freezing Point -110, -79, 194 Critical Temperature 455, 235, 508 Critical Pressure 686, 46.6, 4.73 Specific Gravity 0,922 at 20°C (liquid) Vapor (Specific Gravity 2,6 Ratio of Specific Heats of Vapor (Gas) Latent Heat of Vaporization 176,... 

On the other hand, 1,1,1-trisubstituted alkanes behave similarly to aldehydes, yielding pyrjdium salts (128) with identical substituents in positions 2 and 6. Thus, Dorofeenko and co-workers condensed 2 moles of acetophenone with 1 mole of benzotrichloride in the presence of perchloric acid obtaining 2,4,6-triphenjdpjTylium perchlorate with 1 mole of ethyl orthoformate, they obtained 2,6-diphenyl-pyrylium perchlorate (57) from o-hydroxyacetophenone, ortho-formic ester and perchloric acid, 4-ethoxybenzopyrylium perchlorate was formed. 

Serine is another of the amino acids which Erlenmeyer jun. synthesised in 19O2 from hippuric acid, and which he described in detail with Storp in 1904 by condensing formic ester and hippuric ester with sodium ethylate they obtained oxymethylene hippuric ester or formyl hippuric ester —... 

The reaction sequence is called the Regitz diazo transfer and requires active methylene compounds as substrates/ Hence it is common to use formic esters to create P-carbonyl compounds from ketones or aldehydes in an aldol reaction. These are used as substrates for deformy-lative diazo transfer reactions in which the diazo group is transferred and the formyl group is removed in one concerted step. The mechanism of the deformylative diazo transfer is shown below. In this case the bulky base NaHMDS ensures deprotonation at the less-hindered a-position of 3, forming the so-called kinetic enolate 13. This enolate is formylated by ethyl formate yielding the P-formyl ketone 14, which is used as substrate in the deformylative diazo transfer. 

Formic esters are formed merely by heating the acid with the desired alcohol.797 Ethyl formate, for instance, is obtained by slowly distilling a mixture of ethanol (35 ml), formic acid (20 ml), and water 50 ml, the ester (b.p. 54°) distilling over in 83.4% yield. 

In sulphuric acid solution aldehyde, acetic ester, formic ester, ethylidene oxy-ethyl ether... 

During the condensation of ethyl (3-chloro-2-quinoxaloyl)acetate 35a with ortho-formic ester in the presence of AC2O (65-70 °C), the formation of two substances was observed the main chlorine-containing reaction product 36a and a minor chlorine-free compound 38 (Scheme 3.13). The amoimt of compound 38 increased with increase in temperature, and at 100-105 °C it became the main reaction product. It was also shown that compound 36a can be obtained by heating the initial compound 35a with orthoformic ester at a higher temperamre (100-105 °C). The chain 35a 36a 38 was therefore investigated (Eiden and Bachmann 1973 ... 

Methyl, ethyl, n-propyl, isopropyl, n-hutyl, benzyl, cyclohexyl esters of formic, acetic, oxalic, succinic, tartaric, citric, benzoic, salicylic (and other substituted benzoic acids), phthalic and cinnamic acids phenyl esters of acetic, benzoic and salicylic acids. 

Ethyl formate. Reflux a mixture of 61 g. (50 ml.) of A.R. formic acid (98/100 per cent.) and 31 g. (39-5 ml.) of absolute ethyl alcohol for 24 hours. Transfer to a Claisen flask with fractionating side arm (or attach a fractionating column to the flask), distil and collect the liquid passing over below 62°. Wash the distillate with saturated sodium bicarbonate solution and saturate with salt before removing the ester layer. Dry with anhydrous sodium or magnesium sulphate, filter, and distil. The ethyl formate passes over at 53-54°. The yield is 36 g. 

Hydrogenolysis of the diallyl alkylmalonate 757 with formic acid in boiling dioxane affords the monocarboxylic acid 758. Allyl ethyl malonates are converted into ethyl carboxylates[471]. The malonic allyl ester TV-allylimide 759 undergoes smooth deallylation in refluxing dioxane to give the simple imide 760(472]. The allyl cyanoacetate 761 undergoes smooth decarboxylation to give... 

In addition to high aqueous solubility (7% at 30°C and 38% at 100°C), HgCl2 is very soluble in methyl alcohol (53% at 36°C), ethyl alcohol (34% at 31°C), and amyl alcohol (ca 10% at 30°C). It also is soluble in acetone, formic acid, the lower acetate esters, and other polar organic solvents. 

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