Erythroleukemic cells

K562 (erythroleukemic cells) BITC > MSoPlTC MS3B1TC > eHBlTC > pHBlTC Nastruzzi et al. (82)... 

Dupont, C., Couillerot, E., Gillet, R., Caron, C., Zeches-Hanrot, M., Riou, J.-F. and Trentesaux, Ch. 2005. The benzophenanthridine alkaloid fagaronine induces erythroleukemic cell differentiation by gene activation. Planta Medica, 71 489 94. 

Berg, J., Christoph, T., Widerna, M., Bodenteich, A. Isoenzyme-specific cyclooxygenase inhibitors a whole cell assay system using the human erythroleukemic cell line HEL and the human monocytic cell line Mono Mac 6, J. Pharmacol. Toxicol. Methods 1997, 37, 179-186. 

Several other cultured cell lines were affected by butyrate (5). These included rat glial C6 cells (12-fold increase) and Friend erythroleukemic cells (4-fold increase). The increase in choleragen receptors in Friend cells was also time dependent (Table III). In addition, butyrate appeared to be specific dimethyl-sulfoxide (DMSO) induces erythroid differentiation (23) as does butyrate (24) but it did not cause an increase in toxin receptors (Table 111)7... 

Table III. Binding of Choleragen to Friend Erythroleukemic Cells Treated with Sodium Butyrate or Dimethylsulfoxidea...

Table VII. Effect of Sodium Butyrate on Choleragen Receptors and GM1 Content of Friend Erythroleukemic Cells...

Ganguly et al. [93] demonstrated that (unspecified) tylophora alkaloids could induce apoptosis in a human erythroleukemic cell line (K562) on the basis of nuclear condensation, apoptotic body formation, flipping of membrane phosphatidylserine, activation of caspase 3 and release of mitochondrial cytochrome c. These findings suggest that tylophora alkaloids, in addition to their antiproliferative activity, can also induce apoptosis in certain types of tumor cells. 

Roscetti G, Franzese O, Comandini A, Bonmassar E. Cytotoxic activity of Hypericum perforatum L. on K562 erythroleukemic cells differential effects between methanolic extract and hypericin. Phytother Res 2004 18 66-72. 

Daniels, AJ., Matthews, J.E., Viveros, O.H. Lazarowski, E.R. (1992) Characterization of the neuropeptide Y-induced intracellular calcium release in human erythroleukemic cells. Mol. Pharmacol. 41, 767-771. 

Z. Malik, H. Lugaci (1987). Destruction of erythroleukemic cells by photoactivation of endogenous porphyrins. Br. J. Cancer, 56, 589-595. 

Z. Malik, M. Djaldetti (1979). 5-Aminolevulinic acid stimulation of derivative, and hemoglobin synthesis by uninduced friend erythroleukemic cells. Cell Differ., 8, 223-233. 

Scher W, Friend C (1978) Breakage of DNA and alterations in folded genomes by inducers of differentiation in Friend Erythroleukemic cells. Cancer Res 38 841-849... 

Terada M, Fujiki H, Marks PA, Sugimura T (1979) Induction of erythroid differentiation of murine erythroleukemic cells by nicotinamide and related compounds. Proc Natl Acad Sci USA 76 6411-6414... 

Wintersberger E, Mudrak I (1982) Butyrate does not induce single strand breaks in Friend erythroleukemic cells or in 3T6 mouse fibroblasts. FEBS Lett 138 218-220... 

Conscience JF, Miller RA, Henry J, Ruddle FH (1977) Acetylcholinesterase, carbonic anhyd-rase and catalase activity in Friend erythroleukemic cells, non-erythroid mouse cell lines and their somatic hybrids. Exp Cell Res 105 401-412... 

Bilello JA, Gauri KK, Kuhne J, Warnecke G, Koch G (1982) Induction and inhibition of Friend erythroleukemic cell differentiation by pyrimidine analogs analysis of the requirement for intracellular accumulation and incorporation into DNA. Mol Cell Biol 2 1020-1024... 

Horuk, R., Wang, Z. X., Peiper, S. C., and Hesselgesser, J. (1994) Identification and characterization of a promiscuous chemokine-binding protein in a human erythroleukemic cell line. J. Biol. Chem. 269,17,730-17,733. 

DADS has also reported to induce the differentiation of DS19 mouse erythroleukemic cells (Lea et al. 1999). DADS caused increase in acetylation ofH4 and H3 histones in DS19 cells and K562 human leukemic cells. DADS was more effective than DAS and diallyl sulfone. Histone acetylation was also induced in rat hepatoma and human breast cancer cells by DADS or its metabolite, allyl mercaptan. The allyl mercaptan is a more potent inhibitor of histone deacetylase than DADS. Differentiation in erytiiroleuke-... 

Leder, A., Leder, P., 1975. Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells. 

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