K562 erythroleukemic cells

K562 (erythroleukemic cells) BITC > MSoPlTC MS3B1TC > eHBlTC > pHBlTC Nastruzzi et al. (82)... [Pg.56]

Roscetti G, Franzese O, Comandini A, Bonmassar E. Cytotoxic activity of Hypericum perforatum L. on K562 erythroleukemic cells differential effects between methanolic extract and hypericin. Phytother Res 2004 18 66-72. [Pg.92]

Ganguly et al. [93] demonstrated that (unspecified) tylophora alkaloids could induce apoptosis in a human erythroleukemic cell line (K562) on the basis of nuclear condensation, apoptotic body formation, flipping of membrane phosphatidylserine, activation of caspase 3 and release of mitochondrial cytochrome c. These findings suggest that tylophora alkaloids, in addition to their antiproliferative activity, can also induce apoptosis in certain types of tumor cells. [Pg.29]

DADS has also reported to induce the differentiation of DS19 mouse erythroleukemic cells (Lea et al. 1999). DADS caused increase in acetylation ofH4 and H3 histones in DS19 cells and K562 human leukemic cells. DADS was more effective than DAS and diallyl sulfone. Histone acetylation was also induced in rat hepatoma and human breast cancer cells by DADS or its metabolite, allyl mercaptan. The allyl mercaptan is a more potent inhibitor of histone deacetylase than DADS. Differentiation in erytiiroleuke-... [Pg.442]

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