Dynamic range, sensor

Sun, G., Huang, Y, Zheng, L. et al. 2011. Ultra-sensitive and wide-dynamic-range sensors based on dense arrays of carbon nanotube tips. Nanoscale 3 4854-4858. 

In order to realise such a high dynamic range, either a local compensation coil at the location of the SQUID [9] or a gradiometric excitation coil like the double-D coil have to be used. In case of the electronic compensation, the excitation field and the response of the conducting sample is compensated by a phase shifted current in an additional coil situated close to the SQUID-sensor. Due to the small size of this compensation coil (in our case, the diameter of the coil is about 1 mm), the test object is not affected by it. 

Cg pH-sensitive film had a dynamic range from 6 to 8 and Cg-film responded at higher pH values (8-10).The membranes showed good reproducibility, reversibility and a short response time (<10 s). They also can be used for at least 3 months without any considerable absolution deviations. These sensors can be used for direct determination of pH in drinking water detergent and dishwasher liquid that have good agreement with pH meter data. 

Here r0 is the limiting anisotropy obtained in the absence of rotational motion. The dynamic range of anisotropy sensing is determined by the difference of this parameter observed for free sensor, which is commonly the rapidly rotating unit and the sensor-target complex that exhibits a strongly decreased rate of rotation. 

Na+ and K+ with a detection limit of 10 9 M. The sensor compositions exhibited wide response ranges between 10 9 and 10 5 M Na+ or K+, and, therefore, may be an alternative method to flame emission spectroscopy. The sensor is fully reversible within the dynamic range and the response time is 3 min under batch conditions. Cross sensitivity to pH is negligible in the pH range of 6.2-7.3. 

When compared to fluorescent proteins, fluorophores and quenchers of fluorescence (short quenchers) are small molecules with sizes varying from 1 to 10 A. They are the main building blocks for constructing small molecule FRET probes. As molecular entities, they might influence the performance of the probe to a great extent. Their fluorescent properties will determine the sensitivity and dynamic range of the sensor. The success of the probe for a specific application will depend on the selection of the right fluorophores... 

The aim of this tutorial is to present briefly some of the optoelectronic elements, which can be used for designing of the interfaces for FOCS. More details on optoelectronic devices can be found in the references6 8. Special attention is placed on the appropriate spectral matching of these elements in order to obtain a sensor exhibiting optimal measuring properties such as dynamic range, sensitivity etc. 

The fabrication and characterization of a fiber optic pH sensor based on evanescent wave absorption was presented by Lee63. The unclad portion of a multi-mode optical fibre was coated with the sol-gel doped with pH sensitive dye. The sensitivity of the device increased when the multiple sol-gel coatings were used in the sensing region. The dynamic range and the temporal response of the sensor were investigated for two different dyes -bromocresol purple and bromocresol green. 

Further, the data showed that the optical sensors exhibit satisfactory lifetime. Figure 10.18b shows that the sensors fabricated in May 2001 continued to be functional for three years (at the time of report) in sensing hydrogen at the lower detection limit of 0.1% H2 in air. Although the response time has increased and the dynamic range of coloration has decreased as compared to its original performance, but the sensor itself is still functional. 

The sensors are intended to be built with microresonators of high extinction for a large dynamic range in such case the normalized optical power at the output of the fiber can be express as19... 

First, the decreasing supply voltages tend to reduce the dynamic range of analog circuitry, unless this is compensated for by a substantial increase of power dissipation. Next, device miniaturization enhances, rather than reduces, 1/f noise. Finally, the very high cost of silicon real estate after a deca-nanometer process could become incompatible with the requested size of on-chip sensors. 

Bychkova and Shvarev [16] recently prepared nanosensors (0.2-20 pm) for sodium, potassium and calcium using the precipitation method. Similarly to the previous works, the plasticized poly(vinyl chloride) included a phenoxazine chro-moionophore, a lipophilic ion exchanger and a cation-selective ionophore. The dynamic range of the very selective sensors was 5 x 10 4-0.5 M for sodium, 1 x 10 5-0.1 M for potassium and 2 x 10 4 - 0.05 M for calcium. As was demonstrated by Bakker and co-workers [45] a particle caster can be used can be used for preparation of much larger beads (011 pm). 

Various pH sensors have been built with a fluorescent pH indicator (fluorescein, eosin Y, pyranine, 4-methylumbelliferone, SNARF, carboxy-SNAFL) immobilized at the tip of an optical fiber. The response of a pH sensor corresponds to the titration curve of the indicator, which has a sigmoidal shape with an inflection point for pH = pK , but it should be emphasized that the effective pKa value can be strongly influenced by the physical and chemical properties of the matrix in which the indicator is entrapped (or of the surface on which it is immobilized) without forgetting the dependence on temperature and ionic strength. In solution, the dynamic range is restricted to approximately two pH units, whereas it can be significantly extended (up to four units) when the indicator is immobilized in a microhetero-geneous microenvironment (e.g. a sol-gel matrix). 

A reversible, direct fluoroimmunosensor for human serum albumin (HS A) measurement has been described by Bright et al.(m> Antibody Fab fragments are first immobilized on small quartz plates by hinge-region thiols, and then dansylated. The immunosensor is formed by attaching the quartz plates with bound Fab to the distal end of a bifurcated fiber-optic probe, which transmits both the excitation and emission. Binding of ffSA to the immunosensor results in a three- to five-fold enhancement of dansyl fluorescence. The sensor can be reused up to 50 times, with a detection limit of about 1.8 x 10-8 M, and a somewhat limited dynamic range. 

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