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Drugs penicillins

CS, a 55-year-old woman, is admitted to the hospital with an intraabdominal infection. During the patient interview, CS states that she is allergic to aspirin, codeine, sulfa drugs, penicillin, levofloxacin, and vancomycin. The reactions are described as follows ... [Pg.825]

Endogenous toxins Myoglobin Hemoglobin Drugs Penicillins Ciprofloxacin Sulfonamides Infection Viral Bacterial... [Pg.865]

Bacterial resistance can occur because of several mechanisms.28,76 Certain bacterial strains may be able to enzymatically destroy the antibacterial drug. The best example is the beta-lactamase enzyme that is found in bacteria that are resistant to beta-lactam drugs (penicillins and cephalosporins).54,86 As previously discussed, bacteria containing this enzyme can destroy certain penicillin and cephalosporin drugs, thus rendering the drug ineffective against these strains. [Pg.514]

C, D. Conjugated proteins. Prosthetic group. Hormones epinephrine, thyroxin, insulin, cortisone, ACTH. Chemotherapy. Arsphenamine, sulfanilamide and other sulfa drugs, penicillin, streptomycin, chloramphenicol, aiireomycin. Bacteriostatic action of sulfa drugs through competition with a bacterial growth substance, para-aminobenzoic acid. [Pg.619]

In contrast to other drugs, penicillin-induced skin reactions can occur after more than 1 week of therapy (60). The typical presentation is a maculopapular, erythematous, symmetrically disposed rash on the legs, buttocks, and trunk. [Pg.2760]

S Small lymphocytic lymphoma (WDLL) f Drugs (penicillin)... [Pg.191]

The introduction of the drug penicillin in 1941 was hailed as the dawn of a new era in medicine - an era in which infectious disease could be eradicated for all time. This early optimism proved ingenuous. Sixty years later, infectious diseases are on the rise, particularly in immunocompromised individuals [56]. The Centers for Disease Control has reported that as many as 58% of reported AIDS patients have contracted potentially fatal mycoses [56]. The CDC also reported that the U.S. death rate from infectious diseases increased 60% from 1980 to 1992 [57]. Heart disease and cancer are still the leading causes of death in the Western world. While the primary tissue damage associated with these diseases may be the... [Pg.1146]

Moderately bound drugs Penicillin G 52 Sulphadiazine 45 Phenobarbital 50... [Pg.200]

Figure 7.11. Penicillinases and penicillinase-resistant penicillins. Top Penicillins destroy bacteria after binding to penicillin binding proteins (PBPs). Middle Penicillinases are enzymes produced by bacteria that destroy penicillins by cleaving the beta-lactam ring of the drug. Penicillins are "lured" into the active site because they are chemically similar to penicillin binding proteins. Bottom Clavulinic acid is a "decoy" drug that enhances the activity of penicillins. Clavulinic acid binds to the active sites of penicillinases rendering the enzyme inactive. Figure 7.11. Penicillinases and penicillinase-resistant penicillins. Top Penicillins destroy bacteria after binding to penicillin binding proteins (PBPs). Middle Penicillinases are enzymes produced by bacteria that destroy penicillins by cleaving the beta-lactam ring of the drug. Penicillins are "lured" into the active site because they are chemically similar to penicillin binding proteins. Bottom Clavulinic acid is a "decoy" drug that enhances the activity of penicillins. Clavulinic acid binds to the active sites of penicillinases rendering the enzyme inactive.
During World War II chemists contributed to the Allied effort by developing and producing antibacterials (sulfa drugs, penicillin), antimalarials, and synthetic buna-S (GR-S) rubber. They contributed to the purification of uranium 235 and plutonium 239 as well as the development of conventional explosives needed for the Manhattan Project. [Pg.168]

IR s earliest recognition came during World War II when it provided a key clue to the unusual p-lactam structure of the miracle drug penicillin. [Pg.574]

Viral infections—from influenza and the common cold to the more serious herpes infections and AIDS (acquired immune deficiency syndrome)—account for about 60% of illnesses, contrasted with about 1 5% for bacterial infections. Since the 1 940s, chemists have developed all sorts of highly effective antibiotics (sulfa drugs, penicillins, tetracyclines, and others) that are effective against bacterial infections, but progress with antiviral agents has been slower and more difficult. Why is this so, and what hope do we have for combating viral infections ... [Pg.544]

Allergic reactions may be trivial and local, e.g., a mild nettle-rash or hives (urticaria), or they may be general and so serious as to result in sudden death. Serious reactions are known as anaphylactic shock. Anaphylaxis can be caused by drugs (penicillin and others), horse serum, insect stings, foods (shellfish, nuts, eggs), pollen extracts, and various other agents. [Pg.28]


See other pages where Drugs penicillins is mentioned: [Pg.41]    [Pg.4]    [Pg.1102]    [Pg.296]    [Pg.458]    [Pg.1023]    [Pg.8]    [Pg.221]    [Pg.325]    [Pg.11]    [Pg.42]    [Pg.329]    [Pg.3962]    [Pg.83]    [Pg.3228]    [Pg.1484]    [Pg.254]    [Pg.225]    [Pg.202]    [Pg.209]    [Pg.935]    [Pg.6]    [Pg.73]    [Pg.443]    [Pg.3616]    [Pg.4952]    [Pg.170]    [Pg.3]   
See also in sourсe #XX -- [ Pg.291 ]




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