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Dissection rabbit

Diseases. Liquid crystals have been impHcated in a number of disease conditions in the human body. A complex cholesterol—phosphoHpid—Hpoprotein Hquid crystal phase has been identified in the initiation and maintenance of atheromatous deposits on the aortic intima in dissected human and rabbit arteries (40). The paracrystalHne nature of this precursor to plaque buildup with the resultant loss of arterial elasticity... [Pg.202]

Subcutaneous irritation is evaluated as follows Rabbits are euthanized by a lethal dose of barbiturate approximately 24 and 72 h after dosing. The subcutaneous injection sites are exposed by dissection, and the reaction is scored for irritation on a scale of 0 to 5 as follows (Shintani et al., 1967 USP, 1995a) ... [Pg.387]

Van Julsingha EB, Bennett CB (1977) A dissecting procedure for the detection of abnormalities in the rabbit fetal head. In Neubert DHJ, Marker HJ, Kwasigroch TE (eds) Methods in prenatal toxicology. University of Chicago, Chicago, IL, pp 126-144... [Pg.273]

Male New Zealand White rabbits (2200 g) were exposed to 750 ppm [3.25 g/m ] ethylbenzene for 12 h per day for seven days. Twelve or 24 h following the final day of exposure, the rabbits were killed and their brains dissected. Ethylbenzene depleted both striatal and tubero-infundibular dopamine levels (Mutti et al, 1988). In male Sprague-Dawley rats exposed to 2000 ppm [8.70 g/m ] ethylbenzene for 6 h per day for three consecutive days and killed 16-18 h following the last exposure, ethylbenzene increased dopamine and noradrenaline levels and turnover in the hypothalamus and the median eminence. Ethylbenzene exposure also reduced the secretion of prolactin and increased dopamine turnover within the dopamine-cholecystokinin-8 immunoreactive nerve terminals of the nucleus accumbens (Andersson et al, 1981). [Pg.250]

After its invention by Burg et al. (1966) this technique has been used successfully in the kidney tubule segments of several species man, rabbit, rat, mouse, hamster, snake, birds etc. The tubule segments are dissected from thin kidney slices (< 1 mm thickness). Usually dissection can be done using sharpened forceps or needles without the addition of proteases (collagenase). The segment is identified by its anatom-... [Pg.99]

Male New Zealand rabbits weighing 2-3 kg are eu-thantized under anesthesia and the abdomen is opened to remove the bladder and the urethra. After excess fat and connective tissue is removed, the bladder and the urethra are dissected into dome, trigone and proximal urethral preparations. All strips are cut transversely being approximately 2-6 mm unstretched. [Pg.137]

Spokas and Wun (1992) produced venous thrombosis in the vena cava of rabbits by vascular damage and stasis. The vascular wall was damaged by crushing with hemostat clamps. A segment of the vena cava was looped with two ligatures, 2.5 cm apart. At 2 h after ligation, the isolated venous sac was dissected and the clot removed for determination of dry weight. [Pg.283]

Specific dissection is performed on the brain and pituitary gland. Hypothalamic fragments may be dissected and shock frozen immediately in liquid nitrogen, for later extraction and determination of hypothalamic peptides. The procedure is suitable for the rat and for the rabbit. Immediately after sacrifice, the skull is opened, the brain is removed and the hypothalamic... [Pg.333]

Strips of tissue from the SA nodal region of rabbit heart are dissected and immersed in Tyrode solution at 35°C. By subsequent cuts and ligatures a strip is reduced to a 0.25 x 0.25 mm beating preparation, which is impaled with two standard 3M KCl microelectrodes (about 40 Mohms). Voltage clamp is performed with traditional methods Voltage and current traces are recorded on a two-trace storage oscilloscope and on a 4 FM channel tape recorder for subsequent analysis... [Pg.68]

Lyophilized, anatomically Intact, whole pituitary glands from hogs were kindly supplied by Canada Packers Anterior and posterior were carefully dissected from these when necessary. Isolation of Fractions H and L was exactly as described by Rudman et al. as was the preparation of the rabbits used in the bioassay. The extracts were dissolved in 0.9% NaCI and injected into the marginal ear vein. Blood samples were drawn from the marginal ear vein (except in 10 rabbits by cardiac puncture) and analyzed for FFA (Dole), triglycerides (Van Handel), cholesterol (Abell etal Levine and Zak), lipoproteins (Shandon), glucose, urea and uric acid (E.Seifter et al.). [Pg.441]

The isolated rabbit eye (IRE) test (Burton et al, 1981) determines the opacification of the cornea and the increase in corneal thickness (comeal swelling) after exposure to irritant substances. Whole eyeballs obtained by immediate dissection from humanely killed laboratory rabbits with healthy eyes are mounted and maintained in a vertical position in a superfusion chamber, with controlled temperature and humidity. This ensures that the eyes remain viable throughout the duration of the test. Pre-warmed saline solution is applied drop by drop directly onto the cornea at regular intervals to keep it moist. [Pg.434]


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Dissection

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