Disease categories

If mandatory inclusion laws and African American-only studies are acceptable, then a fortiori there should be few doubts about the permissibility of funding research or treatment of diseases that have an especially high incidence among African Americans. Because not all racial groups are evenly distributed in disease categories, choices to fund some diseases more than others could end up favoring some races and genders over others. 

Lichtenberg (1996) compiled data on hospital deaths and pharmaceutical innovation based on the National Ambulatory Medical Care Survey (NAMCS). For a number of specific disease states, he constructed a measure of pharmaceutical innovation using the dissimilarity between drugs prescribed to the early 1980 cohort in a given disease category, and drugs prescribed in the later 1991 cohort. A greater dissimilarity between... 

Although life expectancy is the best available general measure of health outcomes, no life tables exist by disease. We constructed an alternative measure of disease-specific life expectancy by computing the proportion of deaths that occurred above certain ages, such as 65, using data on deaths by disease category from a time series of mortality data obtained from the Department of Health in Taiwan. ... 

Using the above measures for pharmaceutical innovation and health outcomes, we constructed panel data for disease-specific health outcomes and the cumulative number ofNMEs for each disease category. We hypothesized that diseases associated with a higher rate of pharmaceutical innovations would experience greater improvements in health outcomes. 

Treatment of refractory arthritis-IBD is similar to therapy of other SpA disease categories. Outcomes are similar to AS therapy with SBC-5-IMNs. 

The third part. Developmental Psychopathology, delves into detailed disease-specific overviews. Each of the chapters covers issues pertaining to nosology and classification, to genetic determinants, brain systems implicated, environmental influences, and nature-nurture interactions. Neurotransmission and neuromodulation, and hormonal and other developmental influences are addressed and, whenever available, relevant animal models are incorporated into the discussion. The interplay of normative and derailed development is a core concept for these chapters. Of the part s 12 chapters, 9 are devoted to traditionally defined disease categories, and 3 cover the overarching areas of early-life stress, aggression, and affiliative behaviors. 

Disease Category Source Period transmission Pt Isolation Symptoms Duration (PEP)... 

I telephoned Max Tishler, outlined the situation, and he said he would call back that afternoon. Max contacted the Merck Medical Department, who stated that Wilson s Syndrome was a rare condition affecting only about 50 to 100 patients a year, and was terminal. However, Max was able to launch a crash program to prepare penicillamine at Merck and get quick FDA approval under the "orphan disease category, in spite of the unpromising commercial outlook. 

We will first mention useful mouse models in each of the disease categories listed above, and then describe methods for... 

Designer medicine one potential use of gene expression is to tailor medicine or treatment to individuals, with gene expressions used as explanatory or predictor variables. Microarrays may be used to provide genetic profiles for individual patients, to classify patients into more refined disease categories, or to predict an individual s predisposition to a certain disease. 

However, only determining a provider s adherence to a set of quality indicators for a population with a particular clinical condition is not sufficient. Within a disease category, there are levels of severity and associated morbidity. It is presumed that the sicker the patients, the less likely they might be to exhibit improvements, and therefore less likely to have positive outcomes due to clinical care received. To ensure equitable payment based on the quality of care provided, the severity of illness of a provider s Medi-... 

Indications Thrombotic arterial disease Category Antiplatelet Glycoprotein lib / Ilia inhibitor Half-life 10-30 minutes - given intravenously Clinically important, potentially hazardous interactions with fondaparinux, reteplase... 

Indications Thromboembolic diseases Category Anticoagulant Half-life 8-1 I hours... 

Indications Fabry disease Category Enzyme Half-life 45-102 minutes... 

Indications Nematode infections, hydatid cyst disease Category Antihelmintic Half-life 8-12 hours... 

Indications Gaucher disease Category Enzyme, glucocerebrosidase Half-life 3.6-10.4 minutes... 

Indications Diagnostic aid for coronary artery disease Category Adrenergic beta-receptor agonist Half-life 1.8 hours... 

Indications Infections of the upper and lower respiratory tract, skin infections, sexually transmitted diseases Category Antibiotic, macrolide Half-life 68 hours... 

Trade names Azol Bonzol Cyclomen D-Zol Danocrine Danol Ladogal Winobanin Zoldan-A Indications Endometriosis, fibrocystic breast disease Category Pituitary hormone inhibitor Half-life 4.5 hours... 

Indications Alzheimer s disease Category Cholinesterase inhibitor Half-life 6-8 hours... 

Indications Hyperphosphatemia in end-stage renal disease Category Chelator Half-life 53 hours... 

Trade name Aredia (Novartis) Indications Hypercalcemia, Paget s disease Category Bisphosphonate Half-life 1.6 hours... 

Indications Carcinoma of the pancreas, carcinoid tumor, Hodgkin s disease Category Alkylating agent Half-life 35 minutes... 

Trade name Syprine (Merck) Indications Wilson s disease Category Chelator Half-life N/A... 

Indications Advanced HIV disease Category Antiretroviral Nucleoside analog reverse transcriptase inhibitor Half-life 2.9 hours... 

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