Directional research hypotheses

Of the 13 available attributes, three have direct relevance to the research hypothesis concerning incidence of unbalanced plain-weave fabric. These attributes are the presence of float in one set of yarns of a fabric structure, the presence of a plain weave (defined as a repeated simple alternating) interworking pattern (1/1), and the presence of layers of fabric. If all three are present, there are at least three possible interpretations ... 

Inspection of the fabric attribute dimensions for all location points revealed that certain attributes were either absent or unrecognizable. These attributes are fiber bundle, fiber single, fiber crimp, fiber surface, fiber pattern, yarn type, and yarn twist direction. Therefore, these attributes were deleted from the statistical analysis. The remaining attributes were either present at all location points or exhibited variation. These attributes included the three (layers, 1/1, and float) whose interactive effects had direct relevance to the research hypothesis, and the following fiber and yarn attributes paired fibers, 0 twist, combined yarns, yarn system A, yarn systems A + B, yarn systems A + B + C + D, fabric distortion, red, green, and black. 

This scheme is very simple if compared with the jungle of hypotheses formulated to justify the photochemical isomerization of pentaatomic heterocycles. I do not know if it is true or if it represents a constriction of the nature in a rigid cage. I hope my work will be useful to direct future research efforts in this field. It is not important if future data will confirm or destroy my hypothesis The most important thing is to elicit a discussion. 

A research direction based on a hypothesis over 200 years old, but only recently starting to emerge, proposes to evaluate the role of the MP for optimal visual performance, thus investigating lutein s and zeaxanthin s effects beyond risk reduction of retinal diseases. 

Because oxytocin is a uniquely mammalian hormone with a critical role in both birth and lactation, it was an obvious candidate for involvement in maternal behavior. In fact oxytocin has been termed the hormone of mother love (Klopfer, 1971 Newton, 1973). As mentioned above, animal research offers support for this hypothesis (Pedersen, 1996). However, evidence implicating oxytocin in human behavior only recently has begun to accumulate, and direct evidence for a behavioral effect of oxytocin in humans remains to be demonstrated. 

The recent developments and ideas in the field of prebiotic chemistry can be combined with the concepts noted here to produce what we regard as a research outline, rather than a detailed hypothesis, directed toward a coherent theory of the origin of complex self-contained, self-replicating chiral assemblies. In what follows we present one possible scenario that is consistent with our current knowledge of chiral induction and amplification and with the nature of early Earth as well as early life. It is exciting that this fundamental question can be formulated in a way that allows systematic experimental testing as we enter the next century. 

An alternative mechanism has been proposed by Schneider (1988) who considers that ferritin could be also filled via a transient, mononuclear Fe " species. This species is similar to Fe in size, but is more versatile in its interaction with the protein shell. Experiments have shown that as the pH of a system containing diferric-trans-ferrin and ferritin was lowered very slowly from 7.5 to 5.0, monomeric Fe was released from the transferrin and redeposited in the ferritin (Glaus, 1989). Calculations of the iron flux across the cell membrane and estimates of the rates of interaction of the mononuclear species with ferritin and with the cell mitochondria indicated that the steady state concentration of the mononuclear Fe species would be sufficiently low for this species alone to enter the protein shell and be deposited as the iron core. Uptake of this species by the protein shell is about fiftyfold faster than the rate of hydrolytic polymerization or even of the dimerization of Fe (tiy2 1 vs. 50 ms). This hypothesis suggests an interesting direction for further research. 

As the field of molecular genetics grew, the DNA molecule became the focus of many research efforts. Francis Crick and George Gamov developed the sequence hypothesis to explain how DNA makes protein. They stated that the DNA sequence specifies the amino acid sequence of a protein and postulated the central dogma of molecular genetics the flow of genetic information is a one-way road, it always takes the direction from DNA to RNA to protein [16]. In the same year, 1957, Mathew Meselson and Frank Stahl demonstrated the replication mechanism of DNA [17]. In 1958, DNA polymerase became the first enzyme used to make DNA in a test tube. 

Despite some unexplained or contradictory findings, the dopamine hypothesis still represents the best developed overall theoretical basis on which to explain many biochemical, animal experimental, human pharmacological and clinical findings (McKenna. 1987). Criticism is often directed at the overemphasis on one individual neurotransmitter. i.e. disregard for the fact that the transmitter systems in the CNS work in close mutual interdependence. From the viewpoint of drug research, one might criticize the fact that the dopamine hypothesis is a... 

Despite the hypothesis that the evolutionary significance of phototoxic secondary substances may be linked to their ability to discourage Insect herbivores, most research has been directed toward their effects on human skin and range animals (42). In an attempt to extend our knowledge of insect photosensitizers we have screened a number of plant secondary substances (TABLE TI) for their photosensitizing activity to 4th instar mosquito larvae Aedes atropalpus under solar simulating lamps. 

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