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Directed differentiation of stem

Chai C, Leong KW (2007) Biomaterials approach to expand and direct differentiation of stem cells. Mol Ther 15 467 180. [Pg.308]

Figure 14.19 Simplified schematic overview of the directed differentiation of human embryonic stem cells to form differentiated dopamine like neurons. The full pathway details are available in Yan, Y., Yang, D., Zarnowska, E.D., Du, Z., Werbel, B., Valliere, C., etai 2005. Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells 23, 781-790. FGF fibroblast growth factor SHH sonic hedgehog (a regulatory protein)... Figure 14.19 Simplified schematic overview of the directed differentiation of human embryonic stem cells to form differentiated dopamine like neurons. The full pathway details are available in Yan, Y., Yang, D., Zarnowska, E.D., Du, Z., Werbel, B., Valliere, C., etai 2005. Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells 23, 781-790. FGF fibroblast growth factor SHH sonic hedgehog (a regulatory protein)...
Wichterle, H., Lieberam, I., Porter, J. A. and Jessell, T. M. Directed differentiation of embryonic stem cells into motor neurons. Cell 110 385-397, 2002. [Pg.515]

In the last decade stem cell research has justifiably gained one of the highest scientific profiles both within the medical community and the general public. The ability of stem cells to undergo both self-renewal and differentiation into more functionally specialised mature cells offers tremendous promise in TE. The isolation, expansion and directed differentiation of human stem cells in vitro, however, demand improved understanding of the interplay between the... [Pg.427]

L., Mikesh, M., Marks, A., et al. (2004) Fluorescent proteins expressed in mouse transgenic lines mark subsets of glia, neurons, macrophages, and dendritic cells for vital examination. J Neurosci 24, 10999-11009. Wichterle, H., Lieberam, I., Porter, J. A. and Jessell, T. M. (2002) Directed differentiation of embryonic stem cells into motor neurons. Cell 110, 385-397. [Pg.394]

Hai DC. 2007. Direct differentiation of human embryonic stem cells to hepatocyte-like cells exhibiting functional activities. Cloning Stem Cells 9, 51-62. [Pg.180]

Wichterle H, et al. Directed differentiation of embryonic stem cells... [Pg.1729]

Warren L et al (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7(5) 618-630... [Pg.349]

Mechanical stretching of ceU membranes can be achieved by nanotechnological approaches and it can direct and control the intracellular signaling and differentiation of stem cells 136]. Modifications made to the spatial distribution or cytoskeletal re-organization provide physical impetus, whereby the mechanical deformation becomes translated into biochemical responses [37]. When the cells encounter... [Pg.26]

Lee MR et al (2010) Direct differentiation of human embryonic stem cells into selective neurons on nanoscale ridge/groove pattern arrays. Biomaterials 31(15) 4360 366... [Pg.210]

Lei, F., Haque, R., Xiong, X., Song, J. 2012. Directed differentiation of induced pluripotent stem cells towards T lymphocytes. Journal of Visualized Experiments, (63) e3986. [Pg.344]

I. Karakikes, G. D. Senyei, J. Hansen, C.-W. Kong, E. U. Azeloglu, F. StiUitano, D. K. Lieu, J. Wang, L. Ren, J.-S. Hulot, Small molecule-mediated directed differentiation of human embryonic stem ceUs toward ventricular cardiomyocytes. Stem Cells Transl Med 3, 18-31 (2014). [Pg.361]

L. Warren, P. D. Manos, T. Ahfeldt, Y.-H. Loh, H. Li, F. Lau, W. Ebina, P. K. Mandal, Z. D. Smith, A. Meissner, Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7,... [Pg.363]

Q. Zhang, J. Jiang, P. Han, Q. Yuan, J. Zhang, X. Zhang, Y. Xu, H. Cao, Q. Meng, L. Chen, Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals. Cell Res 21, 579-587 (2011). [Pg.364]

Batchelder CA, Lee CC, Matsell DG, Yoder MC, Tarantal AF. 2009. Renal ontogeny in the rhesus monkey (Macaca mulatta) and directed differentiation of human embryonic stem cells towards kidney precursors. Differentiation 78(l) 45-56. [Pg.379]

Lam, A.Q., Freedman, B.S., Bonventre, J.V., 2014. Directed differentiation of pluripotent stem cells to kidney cells. Semin. Nephrol. 34, 445—461. [Pg.358]

Li, X.J., Hu, B.Y., Jones, S.A., Zhang, Y.S., Lavaute, T., Du, Z.W., Zhang, S.C., 2008. Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules. Stem Cells 26 (4), 886—893. [Pg.539]

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Directed differentiation of stem cells

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