Dioctyl sulphosuccinates

DIOCTYL SULPHOSUCCINATE SIGMA ENGLAND (CH3(CH2)3CH(C2H5)CH2)2C20ljCljH7S03Na 100 - 100 - - -... 

Synonyms. Dioctyl Sodium Sulphosuccinate DSS Sodium Dioctyl Sulphosuccinate. 

SBO SOBITAL SODIUM BIS(2-ETHYLHEXYL) SULFOSUCCINATE SODIUM DI-(2-ETHYLHEXYL) SULFOSUCCINATE SODIUM DIOCTYL SULFOSUCCINATE SODIUM DIOCTYL SULPHOSUCCINATE... 

An example of a surfactant with bulky hydrophobic groups is Aerosol OT (dioctyl sulphosuccinate). If the hydrophilic groups are bulky, as is the case with ethoxylated surfactants containing more than five ethylene oxide units, crowding will occur at the water side of the interface and this will produce an O/W microemulsion. 

Stearate soaps Dodecyl sulphate Dodecylbenzene sulphonate Dioctyl sulphosuccinate Nonyl phenol polyether sulphate Dodecyl polyether phosphate Polyethoxylated alkanol Polyethoxylated nonyl phenol Polyethoxylated polypropylene glycol (pluronic) Glyceryl monolaurate... 

Hussein, M.Z.B. Yun-Hin, T.Y. Tawang, M.M. Shahadan, R. Thermal degradation of (zinc-aluminium-layered double hydroxide-dioctyl sulphosuccinate) nanocomposite. Mater. Chem. Phys. 2002, 74, 265-271. 

The combination present in the laxative Doxidan of dioctyl calcium sulphosuccinate with danthron (1,8-hydroxyanthraquinone) has again been shown to be associated with liver injury almost certainly due to facilitated absorption of the anthraqui-none(24 ). Chronic active hepatitis associated with the use of oxyphenisatin also often occurs in patients whose laxative is combined with dioctyl sulphosuccinates (DSS) (25, 26 ), usuaJly the sodium salt. DSS is excreted in the bile and is toxic in vitro to cultured liver tumour cells (27 -). Oxyphenisatin-induced liver damage may well be promoted by concurrent administration of DSS but chronic active hepatitis can develop during use of oxyphenisatin alone, and challenge with oxyphenisatin alone has induced hepatitis (31). 

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