Sodium dioctyl sulphosuccinate

A dry packed column with porous material was used for the characterization according to size of the PVAc latex samples. The packing employed was CPG (Controlled Pore Glass), 2000 A, 200-400 mesh size. Deionized water with 0.8 gr/lit Aerosol O.T. (dioctyl sodium sulphosuccinate), 0.8 gr/lit sodium nitrate and 0.4 gr/lit sodium azide served as the carrier fluid under a constant flowrate. The sample loop volume was 10 pC A Beckman UV detector operating at 254 nm was connected at the column outlet to monitor particle size. A particle size-mean retention volume calibration curve was constructed from commercially available polystyrene standards. For reasons of comparison, the samples previously characterized by turbidity spectra were also characterized by SEC. A number of injections were repeated to check for the reproducibility of the method. 

Synonyms. Dioctyl Sodium Sulphosuccinate DSS Sodium Dioctyl Sulphosuccinate. 

Alkyl sulphates Dioctyl sodium sulphosuccinate Aerosol OT (AOT) O/T... 

Table 7.1 Effect of poloxamer 188 and dioctyl sodium sulphosuccinate on the absorption of sulphisoxazole from rat intestinal loops ...

Preliminary data obtained by Lish and Weikel [93] indicate that dioctyl sodium sulphosuccinate increases the absorption of sulphathalidine. None of the surfactants studied influenced the absorption of the cationic dye, methyl violet presumably there was interaction with the ionic detergents. The fact that the nonionic surfactant has no effect with either phenol red or methyl violet may be the... 

Aqueous solutions with a surface tension of around 70 mN m do not enter the stomatal pore, but penetration of the pore occurs when the surface tension is lowered by addition of surfactant [243]. The mechanism of penetration is by no means simple. The contact angle between the solution and the surface of the pore is important, but there is a suggestion that the morphology of the pore wall is equally important [244]. However, in the pear Pyrus communis L. cr. Bartlett, stomatal penetration of aqueous solution into leaves was promoted by surfactants according to their surface activity [245]. Dioctyl sodium sulphosuccinate was the most effective surfactant used and Tween 20 least effective. However, only 0.5 to 4.5 % of the stomata were penetrated suggesting that stomatal penetration is, indeed, a relatively unimportant pathway of entry to the leaf. 

Dioctyl sodium sulphosuccinate, C2oH3707SNa, Mol. Wt. 444 6. This is assayed by anionic-cationic titration. The sample solution is titrated against tetra- -butylamInonium iodide solution to which has been added 50 ml of a solution containing 10 per cent anhydrous sodium sulphate and 1 per cent sodium carbonate, in the presence of chloroform, bromophenol blue being used as indicator. 

Docusate sodium (dioctyl sodiirai sulphosuccinate) softens faeces by lowering the surface tension of fluids in the bowel. This allows more water to remain in the faeces. It appears also to have bowel stimulant properties but these are relatively weak. Docusate sodium acts in 1-2 days. Poloxamers, e.g. poloxalkol (poloxamer 188), act similarly and are used in combination with other agents. 

The combination present in the laxative Doxidan of dioctyl calcium sulphosuccinate with danthron (1,8-hydroxyanthraquinone) has again been shown to be associated with liver injury almost certainly due to facilitated absorption of the anthraqui-none(24 ). Chronic active hepatitis associated with the use of oxyphenisatin also often occurs in patients whose laxative is combined with dioctyl sulphosuccinates (DSS) (25, 26 ), usuaJly the sodium salt. DSS is excreted in the bile and is toxic in vitro to cultured liver tumour cells (27 -). Oxyphenisatin-induced liver damage may well be promoted by concurrent administration of DSS but chronic active hepatitis can develop during use of oxyphenisatin alone, and challenge with oxyphenisatin alone has induced hepatitis (31). 

SBO SOBITAL SODIUM BIS(2-ETHYLHEXYL) SULFOSUCCINATE SODIUM DI-(2-ETHYLHEXYL) SULFOSUCCINATE SODIUM DIOCTYL SULFOSUCCINATE SODIUM DIOCTYL SULPHOSUCCINATE... 

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