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Diffractaic acid

Usnea diffracta Dill, ex Adans. U. longissima Acharius Lao Jium Xiu Song Lo (whole plant) Barbaric acid, usnic acid, diffractaic acid, ramalic acid, lichenin.54 Treat throat discharges, malaria, headache, cough, a detoxicant. [Pg.167]

Other Activities. Picrolichenic acid was successfully used against intermittent fever (Alms 1832 Zopf 1907). Pulvinic acid dilactone has a pronounced cardiotonic activity (Nador et al. 1954), secalonic acid A has a phlogistic activity (Harada et al. 1974) and vulpinic acid an antiinflammatory activity (Foden et al. 1975). Usnic and diffractaic acids have analgesic and antipyretic activities comparable to amino-phenazone, phenylbutazone and hydrocortisone hemisuccinate (Dobrescu et al. 1993 Okuyama et al. 1995). [Pg.5]

B, C Diffractaic acid aggregates of long narrow lamellae with curved ends... [Pg.48]

Fig. 24. A 4-0-Demethylbarbatic acid, Py. Bar 100 jim. B Diffractaic acid (from Usnea diffracta Vain.), GE. Bar 100 jim. C Diffractaic acid, GE. Bar lOjim. D Diffractaic acid, Py. Bar 100 jim... Fig. 24. A 4-0-Demethylbarbatic acid, Py. Bar 100 jim. B Diffractaic acid (from Usnea diffracta Vain.), GE. Bar 100 jim. C Diffractaic acid, GE. Bar lOjim. D Diffractaic acid, Py. Bar 100 jim...
Deriv Methyl difffactate, needles (EtOH), mp 127-128 °C, from diffractaic acid with CHjNj in EtjO... [Pg.251]

The best known para-depsides are atranorin, baeomycesic acid, barbatic acid, chloroatranorin, diffractaic acid, squamatic acid and 4-(9-demethylbarbatic acid, while meta-depsides include decarboxythamnolic acid, haemathamnolic acid, hypothamnolic acid and thairmoUc acid. [Pg.11]

Diffractaic acid Analgetic, antiproliferative, antioxidant, antipyretic Brisdelli et al. (2013), Atalay et al. (2011), Kumar and Muller (1999), Okuyama et al. (1995)... [Pg.20]

Brisdelli et al. (2013) investigated the effects of six lichen metabolites (diffractaic acid, lobaric acid, usnic acid, vicanicin, variolaric acid, protolichesterinic acid) on reactive oxygen species (ROS) level towards three human cancer cell lines, MCF-7 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and HCT-116 (colon carcinoma). AU tested lichen compounds did not exhibit free radical scavenging activity using the l,l-diphenyl-2-picrylhydrazyl (DPPH) assay. The lichen metabolites did not significantly increase the intracellular ROS level and did not prevent oxidative injury induced by t-butyl hydroperoxide in tested cells. [Pg.118]

Atalay et al. (2011) determined the lipid peroxidation inhibition potential for nine lichen compounds in two lipid peroxidation test systems (liposome and emulsion systems). They found that isidiophorin, rhizonaldehyde, rhizonyl alcohol and pulmonarianin retarded lipid peroxidation at in both test systems. However, stictic acid and ergosterol peroxide exhibited antioxidant activity in only the liposome test system. Usnic acid and diffractaic acid were not antioxidants in either system, while stictic acid was not lipid peroxidation inhibitor in the emulsion test system. All compounds, which inhibited lipid peroxidation in both test systems, were also DPPH radical scavengers. [Pg.118]

Diffractaic acid (Protousnea magellanica) Vicanicin (Psoroma pallidum) Lobaric acid (Stereocaulon alpinum) Variolaric acid (Ochrolechia deceptionis) Protolichesterinic acid (Cornicularia aculeate) Usnic acid (Cladonia lepidophora) Human breast adenocarcinoma MCF-7 Human colon adenocarcinoma HCT-116 Human cervix adenocarcinoma HeLa Brisdelli et al. (2012)... [Pg.131]

Atranorin (Bacidia stipata) Diffractaic acid (P. magellanica) Divaricatic acid (Protousnea malacea) Vicanicin (Psoroma malacea) Protolichesterinic acid (R. melanophthalma) Human prostate cancer androgen responsive (LNCaP) Human prostate cancer Androgen nonresponsive DU-145 Russo et al. (2012)... [Pg.131]

Depsidones—vicanicin, pannarin, 1-chloropannarin, salazinic acid, stictic acid, variolaric acid, psoromic acid, fumarprotocetiaric acid, lobaric acid Depsides—atranorin, sphaerophorin, divaricatic acid, diffractaic acid gyrophoric acid, usnic acid Hepatocytes from rat Correche et al. (2004)... [Pg.133]

Pannarin, 10 chloropannarin Salazinic acid, psoromic acid Fumarprotocetraic acid, lobaric acid Vicanicin, stictic acid Variolaric acid, atranorin Sphaerophorin, divaricatic acid Diffractaic acid, gyrophoric acid Lymphocytes from rat spleens Correche et al. (2002)... [Pg.133]

Usnic acid Methyl a-orcinolcarboxylate Ethyl hematommate Diffractaic acid (+) Protolichesterinic acid Human keratinocyte cell line HaCaT Kumar and Muller (1999)... [Pg.133]

Kristmundsdottir T, Aradottir HA, Ingolfsdottir K et al (2002) Solubilization of the lichen metabolite (+)-usnic acid for testing in tissue culture. J Pharm Pharmacol 54 1447-1452 Kumar KCS, Muller K (1999) Lichen metabolites. 2. Antiproliferative and cytotoxic activity of gyrophoric, usnic, and diffractaic acid on human keratinocyte growth. J Nat Prod 62 821-823 Kupchan SM, Kopperman HL (1975) 1-usnic acid tumor inhibitor isolated from lichens. Experientia 31 625... [Pg.144]

Usnea diffracta) acid Depsides APP Analgesic activity Otsuka et al. (1972)... [Pg.184]

Diffractaic acid Dibenzofuranes APP Antipyretic activity Y amamoto... [Pg.184]

Heterodea muelleri Barbatic acid Diffractaic acid Usnic acid Depsides Depsides Dibenzofuranes APP APP APP UV-C stress and cold temperature stress Hager et al. (2008)... [Pg.185]

In recent studies, lichen compounds are proved to be a good source of antipyretic, analgesic and anti-inflammatory compounds. Diffractaic acid, usnic acid and... [Pg.191]

Okuyama E, Meyama K, Yamazaki M, Kinoshita Y, Yamamoto Y (1995) Usnic Acid and Diffractaic Acid as Analgesic and Antipyretic Components of Usnea diffiacia. Planta Med 61 113... [Pg.266]

See other pages where Diffractaic acid is mentioned: [Pg.416]    [Pg.500]    [Pg.502]    [Pg.941]    [Pg.942]    [Pg.1264]    [Pg.5]    [Pg.36]    [Pg.48]    [Pg.64]    [Pg.117]    [Pg.251]    [Pg.467]    [Pg.16]    [Pg.18]    [Pg.24]    [Pg.94]    [Pg.95]    [Pg.97]    [Pg.117]    [Pg.120]    [Pg.135]    [Pg.136]    [Pg.200]    [Pg.217]    [Pg.228]   
See also in sourсe #XX -- [ Pg.403 ]

See also in sourсe #XX -- [ Pg.251 ]

See also in sourсe #XX -- [ Pg.217 ]

See also in sourсe #XX -- [ Pg.227 , Pg.228 ]



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