Diethylenetriamine-pentaacetic acid

Brechbiel, M. W., Beitzel, P. M., and Gansow, O. A., Purification of p-nitroben-zyl C-functionalized diethylenetriamine pentaacetic acids for clinical applications using anion-exchange chromatography, J. Chromatogr A, 771, 63,1997. 

Materials. Egg phosphatidylcholine (PC), bovine brain phosphatidylserine (PS) were obtained from Avanti Polar Lipids Inc. (Birmingham, AL) and cholesterol was from Sigma (St. Louis, MO). Ganglioside GMj, bovine, was obtained from Calbiochem (San Diego, CA). Diethylenetriamine pentaacetic acid distearylamide complex (DPTA-SA) was synthesized according to ref. 17 and nlIn-DTPA-SA was prepared as described (7). This lipophilic radiolabel is not transferred to the serum components from liposomes (unpublished data), nor is it rapidly metabolized in vivo (7). The synthesis of N-(glutaryl)phosphatidylethanolamine(NGPE) has been described (18). Dipalmitoyl deoxyfluorouridine(dpFUdR) was synthesized as described (24). 

Singh et al. (2006) also used cycloaddition to prepare carbon nanotubes containing indium labeled diethylenetriamine pentaacetic acid (DTPA) derivatives (Figure 15.17). In the initial modification, a SWNT was derivatized to contain a primary amine at the end of a short PEG spacer. The resultant water-soluble nanotube then was reacted with DTPA to create a metal chelating group at the end of the chain. Subsequent loading of the chelate with mIn created a radionuclide-SWNT complex for in vivo biodistribution studies. 

Gd Magnevist [Gd(III)(DTPA)(H20)]2 DTPA = diethylenetriamine pentaacetic acid MRI contrast agent... 

Chan, H-K., Daviskas, E., Eberl, S., Robinson, M., Bautovich, G., and Young, I.H., Deposition of aqueous aerosol of technetium-99m diethylenetriamine pentaacetic acid generated and delivered by a novel system (AERx) in healthy subjects, Eur. J. Nucl. Med., 26 320-327 (1999). 

DCTA 1,2-diaminocyclohexane tetraacetic acid DBP dibutyl phosphoric acid DTP A diethylenetriamine pentaacetic acid DEHPA di-2-ethylhexyl phosphoric acid... 

AAS = atomic absorption spectrometry DPTA = diethylenetriamine pentaacetic acid HNO3 = nitric acid ICP-AES = inductively coupled plasma-atomic emission spectroscopy Ni = nickel NIOSH = National Institute for Occupational Safety and Health... 

EDTA, ethylenediamine tetraacetic acid NTA, nitrilotriacetic acid HEEDTA, hydroxy-ethylethylene EDTA DTPA, diethylenetriamine pentaacetic acid EDDDA, ethylene diamine-/V,/V -diacetic-/V,/V -dipropionic acid EDDA, /V,/V -ethylene diamine diacetic acid CyDTA, cyclohexylene diamine tetraacetic acid. 

The free ion, Cu2+, appears to be the major species of Cu taken up by plants (Graham, 1981 Jones and Jarvis, 1981). Hence Cu complexation will decrease uptake (DeKock and Mitchell, 1957) unless the complex can dissociate and/or diffuse quickly enough to maintain a constant supply of Cu2+ at the root surface. In the case of Zn, the presence of humic acid (Chen and Aviad, 1990) and carboxylic acids (EDTA, diethylenetriamine pentaacetic acid (DTPA), nitrilotriacetic acid (NTA) DeKock and Mitchell, 1957) has been found to decrease absorption but it is not known whether Zn uptake is correlated with Zn2+ in solution because Zn speciation was not estimated. Other work has shown that Zn initially complexed with citrate is taken up by barley from nutrient solutions (Chairidchai and Ritchie, 1993) and the presence of chelates (EDTA, citrate) can speed up the diffusion of Zn to a root surface in soils (Hodgson et al., 1967 Elgawhary et al., 1970). Speciation in solution is particularly important in the uptake of iron because of its extremely low solubility in the absence of complexing anions... 

Cr Diethylenetriamine-pentaacetic acid Acetate buffer 4 x ht10 37... 

Dose-response relationship The qnantitative relationship between the amonnt of exposnre to a chemical snbstance and the extent of toxic injury or disease in body fnnction or health (response) prodnced DTPA Diethylenetriamine pentaacetic acid... 

Quintana, J.B. and Reemtsma, T. Rapid and sensitive determination of ethylenediamine tetraacetic acid and diethylenetriamine pentaacetic acid in water samples by ion-pair reversed-phase hquid chromatography-electrospray tandem mass spectrometry. /. 

SYNS Ba2797 CALCIUMCHED330 CALCIUM-DTPA CALCIUM TRISODIUM CHEL 330 CALCIUM TRISODIUM DTPA CALCIUM TRISODIUM PENTETATE CALCIUM TRISODIUM SALT of DIETHYLENETRLUVONEPENTAACETIC ACID DIETHYLENETRIAMINE PENTAACETIC ACID, CALCIUM TRISODIUM SALT DITRIPENTAT DTPA CALCIUM TRISODIUM SALT PENTACIN PENTACINE PENTETATE TRISODIUM CALCIUM PENTHAMIL... 

RELATE 80 is an aqueous solution of the pentasodium salt of diethylenetriamine pentaacetic acid. It is more stable to oxidation and forms more stable complexes with some metal ions than EDTA type chelating agents. 

Diethylenetriamine pentaacetic acid, pentasodium salt KELATE Dan River... 

Diethylenetriamine pentaacetic acid pentasodium salt POLYQUEST CNC... 

Diethylenetriamine pentaacetic acid, tetrasodium salt TETRALON Ailied Colloid... 

Tc-DTPA Arterial perfusion accounts for 20%-40% of the circulation in portal hypertension, cirrhosis causes arterial perfusion to increase to over 60%. In portal vein thrombosis, only an arterial curve is visible. Liver metastasis usually displays relatively high arterial perfusion. In (rare) occlusions of the hepatic artery, only a portal venous curve is visible. When a bolus injection of 400 MBq "Tc-diethylenetriamine pentaacetic acid (DTPA) is applied, scintigraphy is able to reveal a bi-phasic time-activity curve. The initial increase of activity is produced by the arterial influence and the second peak by the portal venous inflow. Both curves can be evaluated quantitatively. (36) Perfusion scintigraphy may be useful in the case of liver trauma, TIPS, hyper-vascularized hepatic tumours and partial liver resection as well as after liver transplantation. 

Fig. 4 The nasal clearance of bioadhesive formulations and a control in human volunteers. DTPA = diethylenetriamine-pentaacetic acid. (From Ref. " l)...

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