Development basic concepts

Develop basic concepts about radiation quantities, units, and measurements, about the application of these concepts, and about radiation protection ... 

Edwards and his coworkers first developed basic concepts of wideband models (see Ref. 129). There are different variations of the model, such as the box or exponential wideband models. The underlying idea in these approaches is to represent the gas absorption over a relatively wide spectral band (about 0.1 to 0.5 pm) with a simple function. If this function is an exponential, the resulting model is called as the exponential wideband model [129,133], which is the most well-known and successful of all different models. It is possible to simplify this even further by assuming absorption remains constant over a prescribed wavelength interval. This yields the box model, which is not as good as the former one, as expected. 

Ma S, Chowdhury S. Application of liquid chromatography/mass spectrometry for metabolite identification. In Drug Metabolism in Drug Design and Development Basic Concepts and Practice, Zhang D, Zhu M, Humphreys WG, Eds. Wiley, Hoboken, NJ, 2007 pp.319-367. 

This section describes briefly some of the basic concepts and methods of automatic 3D model builders. However, interested readers are referred to Chapter II, Section 7.1 in the Handbook, where a more detailed description of the approaches to automatic 3D structure generation and the developed program systems is given. 

Development of weighted residual finite element schemes that can yield stable solutions for hyperbolic partial differential equations has been the subject of a considerable amount of research. The most successful outcome of these attempts is the development of the streamline upwinding technique by Brooks and Hughes (1982). The basic concept in the streamline upwinding is to modify the weighting function in the Galerkin scheme as... 

Recent years have witnessed an increase in the number of people using computational chemistry. Many of these newcomers are part-time theoreticians who work on other aspects of chemistry the rest of the time. This increase has been facilitated by the development of computer software that is increasingly easy to use. It is now so easy to do computational chemistry that calculations can be performed with no knowledge of the underlying principles. As a result, many people do not understand even the most basic concepts involved in a calculation. Their work, as a result, is largely unfocused and often third-rate. 

The words basic concepts" in the title define what I mean by fundamental." This is the primary emphasis in this presentation. Practical applications of polymers are cited frequently—after all, it is these applications that make polymers such an important class of chemicals—but in overall content, the stress is on fundamental principles. Foundational" might be another way to describe this. I have not attempted to cover all aspects of polymer science, but the topics that have been discussed lay the foundstion—built on the bedrock of organic and physical chemistry—from which virtually all aspects of the subject are developed. There is an enormous literature in polymer science this book is intended to bridge the gap between the typical undergraduate background in polymers—which frequently amounts to little more than occasional relevant" examples in other courses—and the professional literature on the subject. 

Formaldehyde polymers have been known for some time (1) and early investigations of formaldehyde polymerization contributed significantly to the development of several basic concepts of polymer science (2). Polymers of higher aUphatic homologues of formaldehyde are also well known (3) and frequently referred to as aldehyde polymers (4). Some have curious properties, but none are commercially important. 

The development of combustion theory has led to the appearance of several specialized asymptotic concepts and mathematical methods. An extremely strong temperature dependence for the reaction rate is typical of the theory. This makes direct numerical solution of the equations difficult but at the same time accurate. The basic concept of combustion theory, the idea of a flame moving at a constant velocity independent of the ignition conditions and determined solely by the properties and state of the fuel mixture, is the product of the asymptotic approach (18,19). Theoretical understanding of turbulent combustion involves combining the theory of turbulence and the kinetics of chemical reactions (19—23). 

W. Mendenhall, Introduction to EinearMode/s and the Design andAna/ysis of Experiments, Duxbury Press, Belmont, Calif., 1968. This book provides an introduction to basic concepts and the most popular experimental designs without going into extensive detail. In contrast to most other books, the emphasis in the development of many of the underlying models and analysis methods is on a regression, rather than an analysis-of-variance, viewpoint. 

The chapters presented by different experts in the field have been structured to develop an intuition for the basic principles by discussing the kinematics of shock compression, first from an extremely fundamental level. These principles include the basic concepts of x-t diagrams, shock-wave interactions, and the continuity equations, which allow the synthesis of material-property data from the measurement of the kinematic properties of shock compression. A good understanding of these principles is prerequisite... 

The availability of large and fast computers, in combination with numerical techniques to compute transient, turbulent flow, has made it possible to simulate the process of turbulent, premixed combustion in a gas explosion in more detail. Hjertager (1982) was the first to develop a code for the computation of transient, compressible, turbulent, reactive flow. Its basic concept can be described as follows A gas explosion is a reactive fluid which expands under the influence of energy addition. Energy is supplied by combustion, which is modeled as a one-step conversion process of reactants into combustion products. The conversion (combustion)... 

In order to overcome the special problems posed by brevetoxin B s tetrahydropyran systems, the decision was made to develop and test regio- and stereoselective ring closures employing two types of substrates hydroxy epoxides and hydroxy a,/ -unsaturated esters. The basic concepts of these reactions are shown in Schemes 1 and 2, respectively. 

Fracture mechanic The fracture mechanics theory developed for metals is also adaptable for use with plastics. The basic concepts remain the same, but since metals and plastics are different they require different techniques to describe their fatigue-failure behaviors. Some of the comments made about crack and fracture influences on fatigue performance relate to the theory of fracture mechanics. The fracture mechanics theory method, along with readily... 

The main features of the chemical bonding formed by electron pairs were captured in the early days of quantum mechanics by Heitler and London. Their model, which came to be known, as the valence bond (VB) model in its later versions, will serve as our basic tool for developing potential surfaces for molecules undergoing chemical reactions. Here we will review the basic concepts of VB theory and give examples of potential surfaces for bond-breaking processes. 

This chapter has given reasons and examples for the detailed and comparative analysis of both historical developments of basic concepts and ideas in science and... 

Chapter 3 introduced the basic concepts of scaleup for tubular reactors. The theory developed in this chapter allows scaleup of laminar flow reactors on a more substantive basis. Model-based scaleup supposes that the reactor is reasonably well understood at the pilot scale and that a model of the proposed plant-scale reactor predicts performance that is acceptable, although possibly worse than that achieved in the pilot reactor. So be it. If you trust the model, go for it. The alternative is blind scaleup, where the pilot reactor produces good product and where the scaleup is based on general principles and high hopes. There are situations where blind scaleup is the best choice based on business considerations but given your druthers, go for model-based scaleup. 

The concept of COI was first developed by Rice (Rice 1966, 1967 Rice and Cooper 1967 Rice et al. 1985). It assumes that resources could be used for another purpose if a disease did not exist. Figure 1 demonstrates the basic concept of COI. Most health economic studies assessing the total costs of a disease use this methodology (e.g., Keith and Shackleton 2006 Welte et al. 2000 Leidl et al. 1999 Henke et al. 1997 Xie et al. 1996 Harwood et al. 1983 Hodgson and Meiners 1979). 

---