Deterioration progressive

Appearance of Warburg-type behavior shows that diffusion phenomena become predominant In some coatings as their deterioration progresses. 

In previous decades, a pyramid model dominated the treatment of rheumatoid arthritis. Early in the course of the disease, sahcylates were used to control pain and stiffness. If sahcylates were poorly tolerated or began to lose efficacy, they were discontinued and a different NSAID was used. As the efficacy of NSAID therapy waned and joint deterioration progressed, treatment with a DMARD was added. DMARDs were employed... 

Lasentec Partec 100 was found to give reasonably accurate data for the chord length distribution of sherical particles but the accuracy deteriorated progressively as the shape became more ellipsoidal [123],... 

The deterioration progresses continuously from the surface, and the depth of the deteriorated layer increases in proportion to the square root of exposure time as shown in equations 7- and 8. This parabolic (/t" ) law was obtained as the natural derivation based upon unsteady state dynamics, assuming the simultaneous action of UV-li t and diffusive oxygen. Figure 12 is the least-square plot based on experimental data from Kubota et al. (2.) It can be seen that many polymers show the deterioration by the power law of exposure time (t n = 0.5 - l.O). The difference between theory and experiment is considered to be due to the complex mechanisms not explictly treated in this theory. 

The steel-paste bond is deteriorated progressively under the repeated cycles of reinforced concrete loatlmg the mechanism of load transfer is destroyed arrd the strength of composite decreases [41]. 

Components Do you have established standards for indicating out-of-service conditions for brake system components which deteriorate progressively air leaks, brake shoe wear, drum wear, bearing seal leakage ... 

It is important to distinguish the reversible structure transformation discussed here from other memory phenomena which can be observed intermittently in a variety of contacts which carry an oxide film. In these cases the ON state is often a metal bridge in the breakdown path. The metal originates from the electrodes or by reduction from an oxide film (Whitehead (1951) Sliva et al. (1970)). In this case a reset pulse can restore the high resistance state by burning out the metal bridge. Reproducible memory switch action is unlikely to persist in such a case because the material deteriorates progressively. 

Glucose control in type 2 diabetes deteriorates progressively over time, and, after failure of... 

In this work, the potential for application of Mossbauer spectrometry to corrosion studies was demonstrated for three accelerated corrosion tests in chloride environments. This technique allowed retrieving maximum information from the inherent properties of the rust layers. With VT-MS, it was possible to identify and determine the relative iron phase abundances from which three parameters could be calculated (i) a, (ii) (A + S)/(A + L + S), and (iii) PAI. Moreover, with the physical properties retrieved from the analysis of the hyperfine parameters, it was possible to discuss prospective mechanisms of formation and therefore to contribute to the understanding of the deterioration progress. These studies showed that some corrosion product is lost and/or the conversion of metallic ions into iron oxides may be incomplete, and that the relative iron phase abundances pointed out to a nonprotective and active type of rusts. More work is required on other types and chemistry (composition and abundance of alloying elements) of steels, other environmental conditions, and different exposure times. More efforts are needed to improve the fitting models for nonstoichiometric and substituted iron oxides in rust layers. 

FIGURE 7.4.5 Predictions of the sumulative pareticle size distribution by Manujunath et al (1996) based on closure approximation (7.4.20) compared against stochastic simulation results, alongside population balance predictions. The predictions from the closure approximation for small populations are considerably better than population balance predictions, which deteriorate progressively with time. (Reproduced with permission from Elsevier Science.)... 

Side effects of SMANCS/Lipiodol, when used via the intraarterial route for hepatoma patients, are summarized in Table 4. The major side effect is a low-grade fever, which depends on the procedural technique as well as on the individual patient, namely, some of which may also be due to the immunological host response. If the dose is appropriate, there seems to be little liver toxicity, although many, if not all, liver cancer patients have liver cirrhosis and tend to deteriorate progressively. There seems to be no fatal issue with this therapy. 

Patients with acquired agammaglobulinaemia may have no B cells, but, more commonly, normal numbers of B cells or even increased numbers of B cells are found . In some patients, the B cells do not respond to mitogenic stimuli and do not synthesize immunoglobulin in others, mitotic responses and immunoglobulin synthesis is normal, but there is no secretion of the immunoglobulin formed We have studied one patient whose B cells functioned normally in vitro when cultured in normal AB+ serum, but did not in the patient s serum. His serum contains an inhibitor of his own, as well as normal B cells. Obviously a whole spectrum of B cell maturation failure is presented by these patients. In some patients, T cell function deteriorates progressively. This is particularly true of patients who have an associated thymoma. Other patients have been reported to have suppressor T cells which inhibit normal B cell proliferation in culture The implication is that these patients have normal B cells, but evidence for this has not yet been presented. 

Frequent blood transfusions have to be given to children with severe aplastic anaemia or homozygous thalassaemia to allow for a normal growth pattern and a sufficient quality of life. After puberty, however, the clinical effects of iron deposition appear. Iron deposits are extensive in the ventricular myocardium, but toxic lesions occur also in other organs, particularly in the liver. The condition deteriorates progressively, causing death during adolescence or early adult life (17 ). 

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