Delta opioid receptors

Pello OM, Martinez-Munoz L, Parrillas V, Serrano A, Rodiiguez-Frade JM, Toro MJ, Lucas P, Monterrubio M, Martinez A, MeUado M (2008) Ligand stabilization of CXCR4/delta-opioid receptor heterodimers reveals a mechanism for immune response regulation. Eur J Immunol... 

Tomassini N, Renaud F, Roy S, Loh HH (2004) Morphine inhibits Fc-mediated phagocytosis through mu and delta opioid receptors. J Neuroimmunol 147 131-133 Trillo-Pazos G, Kandanearatchi A, Eyeson J, King D, Vyakamam A, Everall IP (2004) Infection of stationary human brain aggregates with HIV-1 SF162 and IIIB results in transient neuronal damage and neurotoxicity. Neuropathol Appl Neurobiol 30 136-147... 

Zheng H, Chu J, Qiu Y, Loh HH, Law PY (2008) Agonist-selective signaling is determined by the receptor location within the membrane domains. Proc Natl Acad Sci USA 105 9421-9426 Zhu Y, Hsu MS, Pintar JE (1998) Developmental expression of the mu, kappa, and delta opioid receptor mRNAs in mouse. J Neurosci 18 2538-2549... 

Some propeptides produce multiple copies of similar peptides (met-enkephalin and leu-enkephalin act on the same delta opioid receptor). 

Different peptides from the same gene product (met and leu enkephalin, substance P and neurokinin A). The former two act on the same receptor, the delta opioid receptor, whereas the latter act on different receptors, the neurokinin 1 and 2 receptors. Despite this, the receptors for the neurokinins produce the same direction of effect, a slow depolarisation, even though their distribution differs. 

The mu, kappa, and delta opioid receptors have been found to interact with endogenous peptide ligands that share certain pharmacologic properties with opioid drugs. These peptide ligands are derived from at least three different prohormones located in both... 

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Chang KJ, Rigdon GC, Howard JL, McNutt RW. A novel, potent and selective nonpeptidic delta opioid receptor agonist. J Pharmacol Exp Ther 1993 267 852-857. 

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JH. Discriminative stimulus effects of BW373U86 a nonpeptide ligand with selectivity for delta opioid receptors. J Pharmacol Exp Ther 1993 267 888-895. 

Arakawa K, Akami T, Okamoto M, Akioka K, Nakai I, Oka T, Nagase H. Immunosuppression by delta opioid receptor antagonist. Transplant Proc 1993 25 738-740. 

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Sofuoglu M, Portoghese P, Takemori A. Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice evidence for delta opioid receptor subtypes. 

Standifer K, Chien C, Wahlstedt C, Brown G, Pasternak G. Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotide to a delta opioid receptor. Neuron 1994 12 805-810. 

Kaufman D, Xia J, Keith D, Newam D, Evans C, Lusis A. Localization of the delta opioid receptor to mouse chromosome 4 by linkage analysis. Genomics 1994 19 405-406. 

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Tsu R, Chan J, Wong Y. Regulation of multiple effectors by the cloned delta opioid receptor stimulaton of phospholi-... 

Laugwitz K-L, Offermanns S, Spicher K et al. mu and delta opioid receptors differentially couple to G protein sub-types in membranes of human neuroblastoma SH-SY5Ycells. Neuron 1993 10 233-242. 

Law SF, Reisine T. Changes in the association of G protein subunits with the cloned mouse delta opioid receptor upon agonist stimulation. J Pharmacol Exp Ther 1997 281 1476-1486... 

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Human delta opioid receptor Functional studies on stably transfected Chinese hamster ovary cells after acute and chronic treatment with the selective non-peptidic agonist SNC-80. J Pharmacol Exp Ther 1996 278 1083-1089. 

Bot, G, Blake, A, Li, S, Reisine, T. Mutagenesis of the mouse delta opioid receptor converts - buprenorphine from a partial agonist to an antagonist. J Pharmacol Exp Ther 1998 284 283-290. 

Perez, L. and Lysle, D.T., Conditioned immunomodulation Investigations of the role of endogenous activity at mu, kappa, and delta opioid receptor subtypes, J. Neuroimmunol.,19, 101,1997. 

Cvejic, S. and Devi, L. A. (1997) Dimerization of the delta opioid receptor implication for a role in receptor internalization. J. Biol. Chem. 272,26959-26964. 

Delta opioid receptor Agonist analog Diarylmethyl piperazine 23... 

Delta opioid receptor Antagonist analog Hydroxyphenyl piperidine 153... 

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