Degradation quinoline

Pathways and biocatalysts of bacterial degradation quinolines 98AG(E)577. 

It was specifically stated that the proposed metabolic pathway, which suggest C—N bond cleaving and so, a N-specific mechanism, was found when PTA-806 was employed as the biocatalyst. However, when the quinoline-adapted microorganisms, initially isolated from the chemostats (the native P. ayucida), were tested, they were found to fully degrade quinoline, utilizing it as both, a carbon as well as a nitrogen source. 

Shukla [323] isolated an aerobic Gram-negative motile bacterium from sewage which was identified as a P. stutzeri and was found to degrade quinoline by a different pathway, yielding denitrogenated products. 

Pathways and biocatalysts of bacterial degradation quinolines 98AG(E)577. Polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in marine products and estimation of exposure through fishes and shellfishes 97 YZ850. Stereocontrolled synthesis of multifunctional bioactive 7-10-member O-hetero-cycles 97YGK44. 

The cinchona alkaloids on degradation break down into derivatives of (1) quinoline and (2) quinuclidine and the synthesis of any one of them involves the preparation of each of these two halves in a form suitable for combination. 

Trimethyloxazolo[4,5-/]quinoline prepared from 2,7-dimethyl-6-methoxyquinoline using nitration, demethylation (or reversed), reduction, and cy-clization with acetic anhydride confirms unambigously the structure of the aromatic part of the antibiotic X-537A after nitration and alkaline degradation (71JOC3621). 

Direct and derivative spectrophotometric and IP-RP-HPLC methods were applied to identify and determine synthetic dyes and follow their degradation processes. " The dyes considered were Tartrazine (E 102), Quinoline Yellow (E 104), Sunset Yellow (E 110), Carmosine (E 122), Amaranth (E 123), New Coccine (E 124), Patent Blue Violet (E 131), and Brillant Blue ECE (E 133). All are considered representative additives for soft drinks. 

Common additives in food are sulfur S(IV) oxospecies. Quinoline Yellow and Tartrazine show excellent stability toward S(IV) oxospecies while erythrosine. Red 2G, and Green S show good stability. - All other colorants show fair stability, except indigotine, which fades. In the presence of metabisulflte. Sunset Yellow FCF is degraded to a lemon yellow compound identified as l-(4 -sulfo-l-phenylhydrazo)-keto-3,3,4-trihydronaphtalene-4,6-disulfonic acid by NMR and FAB-MS techniques. ... 

Schach S, B Tshisuaka, S Fetzner, F Lingens F (1995) Quinoline 2-oxidoreductase and 2-oxo-l,2-dihydro-quinoline 5,6-dioxygenase from Comamonas testosteroni 63. The first two enzymes in quinoline and 3-methylquinoline degradation. EurJ Biochem 232 536-544. 

The degradation of isoquinoline by Alcaligenes faecalis strain Pa and Pseudomonas diminuta strain 7 (Roger et al. 1990, 1995) is mediated by an oxidoreductase that produces 1,2-dihydroiso-quinoline-l-one, followed by ring fission with the production of o-phthalate and oxidation to 3,4-dihydroxybenzoate (Figure 3.38). The oxidoreductase is purified and like most typical aza-rene oxidoreductases contains, per mole, 0.85 g atoms of Mo, 3.9 g atoms of Fe, and acid-labile S (Lehmann et al. 1994). 

Hund HK, A de Beyer, F Lingens (1990) Microbial metabolism of quinoline and related compounds. VI. Degradation of quinaldine by Arthrobacter sp. Biol Chem Hoppe-Seyler 371 1005-1008. 

Chang H-K, GJ Zylstra (1999) Role of quinolinate phosphoribosyl transferase in degradation of phthalate by Burkholderia cepacia DBOl. J Bacteriol 181 3069-3075. 

Schwarz G, R Bauder, M Speer, TO Rommel, F Lingens 1989 Microbial metabolism of quinoline and related compounds 11. Degradation of quinoline by Pseudomonas fluorescens 3, Pseudomonas putida 86 and Rhodococcus spec. Bl.Biol Chem Hoppe-Seyler 370 1183-1189. 

Benzothiophene is isoelectronic with naphthalene, dibenzothiophene with anthracene, and benzothiazole with quinoline, and this is reflected in their aerobic degradation that is initiated by dioxygenation. The diversity of pathways for the degradation of dibenzothiophene is illustrated by the following examples ... 

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