Deep brain stimulation, in Parkinson’s disease

Toward a Computational Model of Deep Brain Stimulation in Parkinson s Disease... 

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Stefani A, Fedele E, Galati S, Raiteri M, PepiceUi O, Brusa L, Pierantozzi M, Peppe A, Pisani A, Gattoni G, Hainsworth AH, Bemardi G, Stanzione P, Mazzone P (2006) Deep brain stimulation in Parkinson s disease patients biochemical evidence. J Neural Transm Suppl 70 401-408 Steinerman JR, Irizarry M, Scarmeas N, Raju S, Brandt J, Albert M, Blacker D, Hyman B, Stern Y (2008) Distinct pools of beta-amyloid in Alzheimer disease-affected brain a chnicopathologic study. Arch Neurol 65(7) 906-912... 

The Deep-Brain Stimulation for Parkinson s Disease Study Group, Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus paUidus in Parkinson s disease, NEJM, 2001, 345 956-963. 

Ashkan K, Wallace B, Bell BA, Benabid AL. Deep brain stimulation of the subthalamic nucleus in Parkinson s disease 1993-2003 where are we 10 years on Br J Neurosurg. 2004 18 19-34. 

Gross C., Guehl D. Effect of deep brain stimulation on amplitude and frequency characteristics of rest tremor in Parkinson s disease. Thalamus Relat Syst, 2001,... 

HiUcer R, Voges J, Thiel A, GhaemiM, Herholz K, Sturm V, Heiss WD (2002) Deep brain stimulation of the subthalamic nucleus versus levodopa challenge in Parkinson s disease Measuring the on- and off-conditions with FDG-PET. J Neural Transm 109 1257-1264. 

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Benabid, A.L. et al.. Deep brain stimulation of the corpus luysi (subthalamic nucleus) and other targets in Parkinson s disease. Extension to new indications such as dystonia and epilepsy. J. Neurol, 2001,248 (Suppl 3) 11137-11147. 

The use of deep brain stimulation (DBS) as a therapeutic tool in psychiatry is in the early stages of development. The treatment has been used for several years as a neurosurgical procedure, especially in the treatment of movement disorders (e.g., Parkinson s disease), and it is considered by... 

Wolters EC. Deep brain stimulation and continuous dopaminergic stimulation in advanced Parkinson s disease. Parkinsonism Relat D 2007 13 S 18-3. 

Deep brain stimulation—Recently, in 1998, an implantable stimulation device (Activa by Medtronic) was approved by the FDA that can dramatically reduce uncontrollable tremor in patients with Parkinson s disease or essential tremor (Roller et al., 1997). With this device, an electrode array is placed stereotactically into the ventral intermediate nucleus of thalamic region of... 

Nervous system Fentanyl-induced brady-kinesia occurred in a 58-year-old man with advanced Parkinson s disease who was given fentanyl to a total of 300 micrograms over 36 hours for anesthesia and analgesia in conjunction with battery replacement for deep brain stimulation of the subthalamic nucleus the severe akinetic rigid syndrome abated when fentanyl was withdrawn [87 ]. 

One of the most successful commercially available implantable microelectrode arrays is the deep-brain stimulator. Deep-brain stimulation (DBS) uses chronically implanted electrodes to treat neurological conditions such as movement disorders. Electrodes deliver high-frequency electrical stimulation to targeted regions of the brain to treat symptoms of Parkinson s disease. Implantable visual prostheses promise to restore vision by providing stimulation at the retina, optic nerve, or visual cortex. Cochlear implants include an electrode array implanted in the inner ear to stimulate the auditory nerve. Other commercially available implantable neural interfaces include neurostimulation systems for treatment of chronic pain or urinary control. 

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