Regional targeting

The current was applied in the form of electrical pulses in order to permeabilize the membranes of the tumor cells for the entry of the chemotherapeutic agent bleomycin which is a very potent cytotoxic molecule. Clinical complete responses were achieved in 56.4% of the tumors and partial responses were observed in 28.9% of the tumors. This work is thus not strictly electrochemical treatment in the sense of Nordenstrom18 and Xin32 but is rather chemotherapy aided by electrochemical-driven movement of ions, molecules and drugs etc. (e.g., by electroosmosis, electrophoresis) into the tissue regions targeted for necrosis, as in several studies28,51,93 94 described earlier within this chapter. 

Administration to the airspaces of the IPL can be achieved by instillation, forced sprays and aerosol inhalation. These can achieve regional targeting and should be considered carefully and validated at the beginning of experimental programmes. Drugs can also be administered to the lung via the... 

Keywords Pebble, Porphyry Cu-Au-Mo, Regional Targeting, Southwest Alaska, Kahiltna... 

Most of the US cap-and-trade programmes for S02 and NOx used such a one-off allocation. Given the larger value of C02 allowances, the novel experience with a C02 trading scheme and the iterative nature of the definition of national or regional targets, such a one-off allocation was not viable under the ETS. 

Pathogen Host Region Target mutation Detected"... 

Also welcoming the results of the projects implemented by the United Nations regional commissions to assist low-income and middle-income countries in setting their own road traffic casualty reduction targets, as well as regional targets. 

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