Databases Browsing

In contrast to the relational table design of mmCIF, the MMDB data records are structured as hierarchical records. In terms of performance, ASN.l-formatted MMDB files provide for much faster input and output than do mmCIF or PDB records. Their nested hierarchy requires fewer validation steps at load time than the relational scheme in mmCIF or in the PDB file format hence, ASN. 1 files are ideal for three-dimensional structure database browsing. 

The reinaining five search topics (Research Topic, Author Name, Document Identifier, Company Namc/Organii ation, and Browse Table of Contents arc conducted in a similar fashion, with the input being the only difference between the criteria. Thus, in Research Topic" the entry can be any, or even several, keywords or phrases. In "Author Name", literature written by a specific author will be Found, including alternative spelling, Document Identifier" can also be entered directly in the query. Document identifiers arc CA abstract numbers, patent numbers, patent application numbers, or priority application numbers. The last two search topics (Company Name/Organi2ation, and Browse Table ofContents) allow one to search for literature from specific companies or to view the list of journals which are available in the database. 

After return to the Commander window, the reaction retrieval may be executed separately 629 Dicls-Aldcr reactions between aliphatic dienes and cyclic dicno-pliiles are found. This partial result can be narrowed down by restricting tlie reaction conditions by means of the fact editor, The search field codes for the yield and the temperature can be found to be RX.NYD and RX.T, respectively, either by browsing the database structure or by applying the Find option, as described in the first example. To ensure that the retrieved reaction conditions belong to the same experiment, both search terms must be connected by means of the PROXIMITY operator. Before the retrieval is started, the option "Refine results in... 

SciFinder at http //www.cas.org/SCIFINDER/scicover2.html is an easy-to-use desktop research tool that allows the user to explore research topics, browse scientific journals, and access information on the most recent scientific developments. SciFinder Scholar is a desktop research tool designed especially for use by students and faculty to easily access the information in the CAS databases. With either tool, one can search Chemical Abstracts and the CA Registry by author name, research topic, substance identifier, chemical structure, or chemical reaction. 

Health Hotlines directs you to toll-free numbers to over 300 organizations. You can access this database directly at httpy/healthhotlines.nlm.nih.gov/. On this page, you are given the option to search by keyword or by browsing the subject list. When you have received your search results, click on the name of the organization for its description and contact information. 

Many of the bioinformatics programs contain redundant information, so we try to differentiate them based on their applications. Only some of those most commonly used tools are discussed because of space limitation. Web sites mentioned in this chapter were accessed in October 2007. The most recent advances in the field can be updated through browsing these sites regularly as new databases and tools are often added. To facilitate up-to-date bioinformatics support, an integrated search engine and updated collections of tools are freely available at http //sysmed.pharmtao.com. 

Chemscape Server is a communication device that allows a Web server to communicate with ISIS/Host for performing registration, searching, and browsing across a variety of chemical, textual, and relational database types. 

Because formatting within an electronic resume is often minimal, what you say within your resume is what ultimately gets you hired. According to www.eresumes.com, "Keywords are the basis of the electronic search and retrieval process. They provide the context from which to search for a resume in a database, whether the database is a proprietary one that serves a specific purpose, or whether it is a web-based search engine that serves the general public. Keywords are a tool to browse quickly without having to access the complete text. Keywords are used to identify and retrieve resumes for the user. 

The nucleotide sequences can be retrieved from one of the three IC (International Collaboration) nucleotide sequence repositories/databases GenBank, EMBL Nucleotide Sequence Database, and DNA Data Bank of Japan (DDBJ). The retrieval can be conducted via accession numbers or keywords. Keynet (http // www.ba.cnr.it/keynet.html) is a tree browsing database of keywords extracted from... 

On the query form, enter the template PDB ID (either from the CE database or from user s directory) for Chain 1 and enter/browse the query pdb file for Chain 2. 

SciFinder provides an easy interface to search efficiently scientific information without needing to learn complicated issues of database searching of chemical information. Tutorials are available on the web for using Explore by Research Topic, how to set up a Keep Me Posted alert to get breaking news, Browse the Table of Contents of journals, and other SciFinder features. Explore by Chemical Structure allows one to find substances based on their structure to display its physical properties, as well as information on obtaining the substance from commercial sources. CAS STN and SciFinder are considered the most extensive source of chemical information, particularly for information from the patent literature. 

Images of three-dimensional protein structures are often rendered using cartoon-like ribbons to indicate common features of the carbon backbone, such as a-helices and /-i-sheets. Casually browsing the structures illustrated in a biology textbook or an online database, one is struck by the frequent appearance of the right-handed helical structures known as a-helices. The structural features of a-helices are illustrated in Figures 10.1 and 10.2. 

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