Corticotropin-releasing factor receptors

Coronary circulation, 6 (1969) 11 Corticotropin releasing factor receptor antagonists, 41 (2003) 195 Coumarins, metabolism and biological actions, 10 (1974) 85 Cyclic AMP, 12 (1975) 293 Cyclooxygenase-2 (COX-2) inhibitors, 36 (1999) 201... [Pg.387]

J. P. Whitten, Y. E Xie, P. E. Erickson, T. R. Webb, E. B. De Souza, D. E. Grigoriadis, J. R. McCarthy, Rapid Microscale Synthesis, a New Method for Lead Optimization Using Robotics and Solution Phase Chemistry Application to the Synthesis and Optimization of Corticotropin-Releasing Factor Receptor Antagonists , J. Med. Chem. 1996,39, 4354-4357. [Pg.77]

Reul JMHM, Holsboer F (2002) Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr Opin Pharmacol 2 23-33 Rodgers RJ, Cole JC (1994) The elevated plus-maze pharmacology, methodology and ethology. In Cooper SJ, Hendrie CA (eds) Ethology and psychopharmacology. John Wiley and Sons, Chichester, pp 9-44... [Pg.68]

Bale TL, Contarino A, Smith GW, Chan R, Gold LH, Sawchenko PE, Koob GF, Vale WW, Lee KF (2000) Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress. Nat Genet 24 410-414 Bale TL, Picetti R, Contarino A, Koob GF, Vale WW, Lee KF (2002) Mice deficient for both corticotropin-releasing factor receptor 1 (CRFRl) and CRFR2 have an impaired stress response and display dichotomous anxiety-like behavior. J Neurosci 22 193-199 Barberis C, Tribollet M (1996) Vasopressin and oxytocin receptors in the central nervous system. Grit RevNeurobiol 10 119-154... [Pg.133]

Contarino A, Dellu P, Koob G P, Smith GW, Lee KP, Vale W, Gold LH (1999) Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1. Brain Res 835 1-9... [Pg.134]

Smith GW, Aubry J-M, Dellu F, Contarino A, BUezikijan LM, Gold LH, Chen R, Marchuk Y, Flauser C, Bentley CA, Sawchenko PE, Koob GF, Vale WW, Lee KF (1998) Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron 20 1093-1102... [Pg.140]

Isogawa K, Akiyoshi J, Hikichi T, Yamamoto Y, Tsutsumi T, Nagayama H (2000) Effect of corticotropin releasing factor receptor 1 antagonist on extracellular norepinephrine, dopamine and serotonin in hippocampus and prefrontal cortex of rats in vivo. Neuropeptides 34 234-239... [Pg.201]

Chen F, Bilezikjian LM, Perrin MH, Rivier J, Vale W (1986) Corticotropin releasing factor receptor-mediated stimulation of adenylate cyclase activity in the rat brain. Brain Res 381 49-57... [Pg.329]

Reul, J.M., Holsboer, F. Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr. Opin. Pharmacol. 2, 23-33, 2002. [Pg.360]

Webster EL, Grigoriadis DE, De Souza EB. Corticotropin-releasing factor receptors in the brain-pituitary-immune axis. In McCubbin JA, Kaufmann PJ, Nemeroff... [Pg.148]

The first published report on the utilization of the HP 7686 Solution-Phase Synthesizer (Figure 13.1) for lead optimization of corticotropin-releasing factor receptor antagonists appeared in 1996 [13]. Scientists from Neurocrine... [Pg.320]

Whitten JP, Yon Feng Xie, Erickson PE, Webb TR, De Souza EB, Grigariadis DE, McCarthy JR, Rapid microscale synthesis, a new method for lead optimization using robotics and solution phase chemistry application to the synthesis and optimization of corticotropin-releasing factor, receptor antagonists, J. Med. Chem., 39 4354-4357, 1996. [Pg.342]

De Souza EB (1987) Corticotropin-releasing factor receptors in the rat central nervous system characterization and regional distribution. J Neurosci 7(1) 88—100... [Pg.335]

Hauger RL, Millan MA, Lorang M, Harwood JP, Aguilera G (1988) Corticotropin-releasing factor receptors and pituitary adrenal responses during immobilization stress. Endocrinology 123(1) 396—405... [Pg.335]

Millan MA, Jacobowitz DM, Hauger RL, Catt KJ, Aguilera G (1986) Distribution of corticotropin-releasing factor receptors in primate brain. Proc Natl Acad Sci USA 83(6) 1921—5... [Pg.335]

Bale TL, Picetti R, Contarino A, Koob GE, Vale WW, Lee KF. Mice deficient for both corticotropin-releasing factor receptor... [Pg.2260]

Yu. J. et al (1996) Molecular cloning of a type A chicken corticotropin-releasing factor receptor with high afTinity for urotensin I. Endocrinology. 137.192-197. Alexander. S.P.H. et al. (1998) Receptors and ion channel nomenclature supplement. Ninth Edition. Tren Pharmacol. ci.. Suppl.. 19.1 -98. [Pg.85]

Lundkvist. J. et al. (1996) A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity. Eur. J. Pharmacol.. 309.195-200. [Pg.85]

Dieterich KD, Lehnert H, De Souza EB.Corticotropin-releasing factor receptors An overview. Exp. Clin. Endocrinol. Diabetes 1997 105 65-82. [Pg.2001]

Eghbal-Ahmadi M, Hatalski CG, Avishai-Eliner S, Baram TZ. Corticotropin releasing factor receptor type II (CRF2) messenger ribonucleic acid levels in the hypothalamic ventromedial nucleus of the infantrat are reduced by maternal deprivation [published erratum appears in Endocrinology]. Endocrinology 1997 138 5048-5051 erratum 1998 139(i) 136. [Pg.396]

De Souza, E. B., Grigoriadis, D. E., and Webster, E. L. (1991). Role of brain, pituitary and spleen corticotropin-releasing factor receptors in the stress response. Methods Achiev. Exp. Pathol. 14, 23-44. [Pg.32]

DeSouza EB, Insel TR, Perrin MH, Rivier J, Vale WW, Kuhar MJ (1985) Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system An autoradiographic study. J. Neurosci., 5, 3189-3208. [Pg.324]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...